Please note: a valid prescription is required for all prescription medication.
Tradjenta® is the brand name for linagliptin, a once-daily tablet for type 2 diabetes. This page helps you compare options, check cost, and buy Tradjenta online from Canada with US shipping. Many patients look for pricing that works without insurance while keeping their care consistent.
CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.
What Tradjenta® Is and How It Works
Tradjenta® belongs to a class called DPP-4 inhibitors. It helps your body increase insulin release after meals and reduce glucose made by the liver. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes. You can take it alone or with other diabetes medicines.
Linagliptin targets the DPP-4 enzyme. Blocking DPP-4 raises natural incretin hormones, which support insulin secretion when glucose is high. This effect is glucose-dependent, so it has a low risk of hypoglycemia by itself. Learn more about classes and choices in Oral Diabetes Medications.
Who Tradjenta® Is For
Tradjenta is for adults with type 2 diabetes who need better A1C control despite diet and exercise. It may be used as initial therapy or added to agents such as metformin, SGLT2 inhibitors, or basal insulin.
Do not use Tradjenta if you have had a serious allergic reaction to linagliptin. People with a history of pancreatitis should discuss risks and alternatives with their clinician. It is not for type 1 diabetes or diabetic ketoacidosis. For background on the condition itself, see our Type 2 Diabetes category.
Dosage and Usage
The usual adult dose is 5 mg by mouth once daily, with or without food. Take at the same time each day for consistency. No dose adjustment is typically needed for kidney or liver impairment, but follow your prescriber’s guidance.
When used with a sulfonylurea or insulin, your clinician may lower those agents to reduce hypoglycemia risk. Always follow the treatment plan on your prescription. For more detail on labeled schedules, see Tradjenta Dose.
Strengths and Forms
Tradjenta is supplied as film-coated oral tablets. Commonly available strength:
- 5 mg tablet
Availability and packaging can vary by manufacturer or country. Stock and presentation may change.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once.
Storage and Travel Basics
Store tablets at room temperature in a dry place. Keep the bottle or blister sealed when not in use. Protect from moisture and excessive heat. When you travel, carry your medication in original labeled packaging and keep it in your carry-on bag. If you are crossing borders, bring a copy of your prescription for screening.
Benefits
- Once-daily dosing with or without food
- Low intrinsic risk of hypoglycemia when used alone
- Can be combined with metformin, SGLT2 inhibitors, or basal insulin
- No routine dose adjustment for kidney or liver impairment per label
Side Effects and Safety
Common side effects are usually mild and may include:
- Nasopharyngitis or mild respiratory symptoms
- Cough or sore throat
- Headache
- Joint or muscle aches
- Diarrhea
Serious but less common risks include pancreatitis, severe joint pain, bullous pemphigoid, and allergic reactions such as angioedema. Stop the medicine and seek medical help if you have severe abdominal pain, blistering skin, or signs of hypersensitivity. When combined with insulin or a sulfonylurea, low blood sugar can occur. Know the signs of hypoglycemia and how to treat it.
For a deeper look at possible reactions, review Side Effects Tradjenta.
Drug Interactions and Cautions
Tell your clinician and pharmacist about all medicines and supplements you use. Notable considerations include:
- Insulin and sulfonylureas: increased risk of hypoglycemia; prescriber may adjust those agents
- Strong inducers of P-gp/CYP3A4 (for example rifampin): may reduce linagliptin exposure and effectiveness
- History of pancreatitis: weigh risks and monitor for symptoms
- Severe skin reactions or allergy history: discontinue and seek care if symptoms occur
Alcohol can raise or lower blood sugar and may complicate control. Discuss limits that fit your plan.
What to Expect Over Time
Many people see steady improvements in fasting and post-meal glucose as part of a broader plan. A1C changes are assessed over several months. Tradjenta works best with consistent diet, activity, and follow-up. If targets are not met, your prescriber may add or adjust therapies.
Compare With Alternatives
Other DPP-4 options and foundational therapies may suit different needs. Within the same class, Januvia® is a widely used alternative. As a baseline therapy, Metformin is often first-line and can be combined with DPP-4 inhibitors.
For a side-by-side overview, read Tradjenta Vs Januvia.
Pricing and Access
You can buy Tradjenta online with Canadian pricing and US delivery from Canada. Many patients compare Tradjenta cost to alternatives to manage out-of-pocket spending. Check our current Tradjenta price and see available strengths before you order. Savings may be meaningful for those paying without insurance.
Place your request, upload your prescription, and we will coordinate verification with your clinic. Our encrypted checkout protects your information from start to finish.
Availability and Substitutions
Supply can vary. If Tradjenta is temporarily unavailable, your prescriber may recommend a suitable alternative in the same class or a different class based on your history. We can coordinate a change only with your clinician’s approval.
Patient Suitability and Cost Saving Tips
Good candidates are adults with type 2 diabetes who need additional glucose control without frequent lows. It may be an option if you cannot tolerate metformin or need an add-on. It is not for type 1 diabetes or for treating diabetic ketoacidosis.
- Ask about multi-month fills to lower per-unit cost
- Use refill reminders to avoid lapses that disrupt control
- Combine with lifestyle measures to maximize benefit
- Review all medicines each visit to streamline your regimen
Explore broader treatment topics in our Diabetes section.
Questions to Ask Your Clinician
- Is Tradjenta appropriate for my A1C and current regimen?
- Should I adjust insulin or a sulfonylurea to reduce low blood sugar risk?
- What signs of pancreatitis or allergic reaction should I watch for?
- How will we monitor kidney function, liver function, and A1C over time?
- When should we consider adding or switching to another class?
- Are there dietary steps that match my medications?
Authoritative Sources
- FDA DailyMed: Tradjenta (linagliptin)
- Boehringer Ingelheim: Tradjenta Product Information
- Health Canada Drug Product Database: Tradjenta
Ready to get started? Place your request today for US delivery from Canada, and we will verify your prescription with your clinic.
Disclaimer: This page is educational and does not replace professional medical advice. Always follow your prescriber’s instructions and the official label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What is Tradjenta used for?
Tradjenta (linagliptin) is a DPP-4 inhibitor used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
How do I take Tradjenta?
The usual dose is 5 mg by mouth once daily, with or without food. Take it at the same time each day unless your clinician advises otherwise.
What are common Tradjenta side effects?
Common effects include runny or stuffy nose, cough, headache, and mild digestive symptoms. Seek care for severe abdominal pain, allergic reactions, or blistering skin.
Can I use Tradjenta with metformin or insulin?
Yes, it is often combined with metformin and can be used with insulin. Your clinician may adjust insulin or sulfonylurea doses to reduce hypoglycemia risk.
What if I miss a dose of Tradjenta?
Take it when you remember the same day. If it is close to your next dose, skip the missed dose. Do not double up.
How should I store Tradjenta tablets?
Store at room temperature in a dry place. Keep tablets in the original bottle or blister and protect from heat and moisture.
Do you ship Tradjenta from Canada to the US?
Yes. You can buy Tradjenta online with Canadian pricing, and we arrange US delivery from Canada after we verify a valid prescription.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
You Might Also Like
Related Articles
Diabetic Eye Disease Month: Protect Your Vision Today
Vision is one of our most precious senses, yet millions of people with diabetes are at risk of losing it without even realizing it. According to the Centers for Disease…
Join the Cause: American Diabetes Month 2025
Every November, millions of Americans come together to shine a light on one of the country’s most pressing health challenges — diabetes. American Diabetes Month is more than just a…
Orforglipron vs Rybelsus: Which Is More Effective?
According to the International Diabetes Federation (IDF), around 589 million adults aged 20–79 are living with diabetes globally. This marks the need for immediate medical action and treatment. Fortunately, with…
How to Travel with Ozempic: Keep Your Dose Effective
Vacations, business trips, and weekend getaways shouldn’t interfere with your health routine. For people using Ozempic, planning ahead is key to keeping your medication safe and effective while on the…





