Wellbutrin XL is a brand name for the extended-release formulation of bupropion, an antidepressant developed by GlaxoSmithKline. Approved by the FDA, Wellbutrin XL is used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It works by influencing neurotransmitters in the brain, primarily norepinephrine and dopamine. Unlike some other antidepressants, Wellbutrin XL is less likely to cause sexual side effects or weight gain. The extended-release formulation allows for once-daily dosing, providing steady medication levels throughout the day.