Please note: a valid prescription is required for all prescription medication.
Pravastatin is a statin used to lower LDL cholesterol and triglycerides. At CanadianInsulin, Pravachol® (pravastatin) is supplied from Canada and ships to the US, with US delivery from Canada and Canadian pricing. Many patients also compare options when paying without insurance.
What Pravastatin Is and How It Works
Pravastatin belongs to the HMG-CoA reductase inhibitor class, often called statins. It reduces liver production of cholesterol, which lowers LDL and total cholesterol. It can modestly raise HDL and lower triglycerides. Pravastatin also helps slow plaque progression in blood vessels.
At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.
Clinicians prescribe pravastatin for primary hyperlipidemia, mixed dyslipidemia, and for cardiovascular risk reduction in appropriate patients. It is often part of a long-term plan that includes diet, activity, and weight management.
Who Pravastatin Is For
Pravastatin is used in adults with high cholesterol or mixed lipid disorders. It is also used in certain pediatric patients with heterozygous familial hypercholesterolemia when lifestyle measures alone are not sufficient. Treatment aims to reduce LDL and overall cardiovascular risk.
It is not appropriate for people with active liver disease or unexplained persistent elevations of liver enzymes. Statins are generally not recommended during pregnancy or breastfeeding. People with a history of serious muscle problems on a statin need careful evaluation before use.
For related options, see our Cholesterol category.
Dosage and Usage
Many adults start at 40 mg once daily. Some begin lower based on clinical factors, with adjustments over time. The typical range spans 10 mg to 80 mg daily. Dosing may be lower in severe renal impairment or when used with certain interacting medicines.
Swallow tablets whole with water. Pravastatin can be taken with or without food. Take it at the same time each day. Many patients take statins in the evening, though timing can be individualized. A clinician may adjust the dose after reviewing lipid panels and treatment goals.
When pravastatin is combined with bile acid sequestrants such as cholestyramine or colestipol, doses are usually separated to reduce binding in the gut. Follow the prescriber’s schedule.
Strengths and Forms
Pravastatin is supplied as oral tablets. Commonly available strengths include:
- 10 mg tablets
- 20 mg tablets
- 40 mg tablets
- 80 mg tablets
Availability can vary by manufacturer and lot. Packaging and tablet imprints may differ.
Missed Dose and Timing
If a dose is missed, take it when remembered unless it is close to the next scheduled dose. If it is near the next dose, skip the missed dose. Do not double the dose. Consistent daily dosing supports steady lipid control.
Storage and Travel Basics
Store tablets at room temperature, typically 20 to 25°C (68 to 77°F). Keep the bottle tightly closed and away from excess moisture and heat. Do not store in a bathroom.
When traveling, keep your medication in your carry-on bag. Carry your prescription label or a copy of your prescription. Use the original container for security checks. If you use a weekly pill organizer, also carry the labeled bottle for reference.
Benefits
- Lowers LDL cholesterol, a key driver of atherosclerosis
- Reduces total cholesterol and triglycerides
- Can modestly raise HDL cholesterol
- Supports cardiovascular risk reduction in appropriate patients
- Once-daily dosing with or without food
- Fewer CYP3A4 interactions than some other statins
Side Effects and Safety
- Headache
- Nausea or stomach discomfort
- Diarrhea or constipation
- Fatigue
- Muscle aches or cramps
- Upper respiratory symptoms
Serious effects are uncommon but include myopathy or rhabdomyolysis, especially with interacting drugs or certain medical conditions. Liver enzyme elevations can occur. Memory issues and elevations in blood sugar have been reported. Seek medical care for unexplained muscle pain, weakness, dark urine, or jaundice. An overview of statins and diabetes risk is discussed in Statin Drugs Diabetes.
Drug Interactions and Cautions
Tell the prescriber about all medicines, vitamins, and supplements. Important interactions include:
- Immunosuppressants such as cyclosporine, which can raise statin levels
- Macrolide antibiotics (for example, clarithromycin and erythromycin)
- Some antifungals
- Fibrates and high-dose niacin, which increase muscle-related risk
- Bile acid sequestrants, which can reduce pravastatin absorption
If used with a fibrate, clinicians often review risks closely. See information on Fenofibrate for context about this drug class. With bile acid sequestrants, dose separation is typically recommended. Alcohol can stress the liver and may add risk when used excessively.
Report prior statin intolerance, kidney problems, thyroid disease, or heavy alcohol use. A clinician may order baseline and follow-up labs as needed.
What to Expect Over Time
LDL reductions often begin within 1 to 2 weeks. The full lipid-lowering effect is usually seen after about 4 weeks of stable dosing. Clinicians typically recheck lipids after dose changes, then periodically. Dose adjustments may occur to reach target ranges.
Some patients need stronger LDL reduction and may be prescribed a higher-intensity statin such as Lipitor® or may combine therapies. Background reading on statins is available in Lipitor Uses.
Compare With Alternatives
Several lipid-lowering options exist when pravastatin is not suitable or when LDL goals are not met:
- Crestor® (rosuvastatin) is a high-intensity statin at certain doses and offers strong LDL lowering.
- Ezetimibe blocks cholesterol absorption in the gut and can be added to a statin when further LDL reduction is needed.
Choice depends on lipid levels, overall risk, tolerability, and coexisting conditions. A clinician can tailor therapy to individual needs.
Pricing and Access
Canadian pricing with US delivery from Canada helps many patients compare out-of-pocket costs. On this page, shoppers can check pravastatin 40 mg price and pravastatin 40 mg tablet price in one place. It is simple to order pravastatin 40 mg online with US shipping from Canada. Listings may include pravastatin sodium 40 mg price, pravastatin 40 mg cost, and pravastatin 40 mg cash price across available pack sizes.
People often compare Pravachol 40 mg price and generic Pravachol 40 mg price to understand value. Some look for pravastatin 40 mg online price or pravastatin 40 mg discount price when promotions are available. If larger quantities are available, the pravastatin 40 mg 90 tablets price can be reviewed on the product page. For convenience, pravastatin 40 mg mail order supports home delivery. Many also check pravastatin 40 mg price without insurance to plan budgets.
Pravastatin 40 mg from Canada ships to the US through our prescription referral service, providing prompt, express shipping. Checkout uses encrypted checkout for payment security. For current savings, see our Promotions page.
Availability and Substitutions
If a specific strength or pack size is unavailable, a prescriber may recommend an alternative strength or an appropriate substitute. Pharmacy stock can change by manufacturer and lot. We do not guarantee restock timelines.
Patient Suitability and Cost Saving Tips
Pravastatin may be suitable for adults with elevated LDL or mixed dyslipidemia and for certain pediatric patients under specialist guidance. It may be less suitable for those with active liver disease, prior severe statin-related muscle injury, or during pregnancy or breastfeeding.
To manage cost, many patients choose a multi-month supply when appropriate, which can lower per-tablet pricing. Setting refill reminders helps avoid gaps in therapy. Using the same pharmacy source can keep tablets and imprints consistent across refills.
Questions to Ask Your Clinician
- What LDL and non-HDL targets fit the current risk profile?
- Is pravastatin 40 mg an appropriate starting dose, or should dosing begin lower?
- How often should lipids and liver enzymes be checked?
- Should dosing be in the evening or can it be taken at any time?
- Are there medicines or supplements that should be spaced or avoided?
- What lifestyle changes will best support LDL reduction?
- What signs of muscle or liver issues should prompt immediate evaluation?
Authoritative Sources
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What does pravastatin treat?
Pravastatin treats primary hyperlipidemia and mixed dyslipidemia. It also supports cardiovascular risk reduction in appropriate adults and some pediatric patients with familial hypercholesterolemia, alongside diet and lifestyle measures.
Is 40 mg of pravastatin a common dose?
Yes. Many adults start at 40 mg once daily, with adjustments based on lipid response, tolerability, interactions, and clinical goals. Lower starting doses are used in some situations.
How long before cholesterol improves on pravastatin?
LDL often starts to fall within 1 to 2 weeks, with the full effect generally seen after about 4 weeks of stable dosing. Clinicians usually recheck lipids after dose changes.
Can pravastatin be taken with food or in the morning?
Pravastatin can be taken with or without food. It may be taken at any consistent time of day. Many patients use evening dosing, but timing can be individualized.
What are serious risks with pravastatin?
Serious but uncommon risks include myopathy or rhabdomyolysis and liver enzyme elevations. Seek care for unexplained muscle pain, weakness, dark urine, or jaundice.
Is pravastatin safe during pregnancy or breastfeeding?
Statins are generally not recommended during pregnancy or breastfeeding. Clinicians typically discontinue therapy when pregnancy is recognized and reassess after delivery.
Can pravastatin be used with ezetimibe or a fibrate?
Ezetimibe is often added when more LDL lowering is needed. Fibrates may be used in select cases, but the combination can increase muscle risk and needs careful oversight.
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