Nobivac® Canine 1-DAPPv Vaccine for Dogs

Nobivac® Canine 1-DAPPv is a core combination vaccine for dogs. It helps protect against canine distemper, adenovirus, parainfluenza, and parvovirus. CanadianInsulin offers Canadian pricing and ships from Canada to the US with US delivery from Canada, using prompt, express, cold-chain shipping so doses arrive properly handled. You can order online even when paying without insurance.

What Nobivac® Is and How It Works

Nobivac® Canine 1-DAPPv is a five-way canine vaccine from Merck Animal Health. It contains modified live viruses that stimulate active immunity against four major diseases: distemper (CDV), adenovirus (CAV-2, cross-protects for hepatitis), parainfluenza (CPiV), and parvovirus (CPV). This DAPPv dog vaccine is widely used as part of routine canine preventive care.

At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.

After reconstitution with the supplied sterile diluent, the 1 mL dose is administered by a veterinary professional. The immune system recognizes the vaccine antigens and builds protective antibodies and cellular responses. Completing the initial series and timely boosters supports sustained protection. Always vaccinate healthy dogs, as directed by a veterinarian.

Who Nobivac® Is For

This vaccine is indicated for the vaccination of healthy dogs, including puppies and adults, against distemper, adenovirus, parainfluenza, and parvovirus. It is a standard component of a core DAPPv schedule for dogs across most practice settings, including clinics, shelters, and kennels.

Use in healthy animals only. Postpone vaccination for dogs with fever or acute illness. Discuss risks and timing for pregnant or lactating bitches with a veterinarian. Dogs with a history of hypersensitivity reactions should be evaluated before any vaccine. This product is for dogs; it is not for cats or other species.

DAPPv vaccination is one part of a broader prevention plan that can also include parasite control and lifestyle measures. For parasite education, see our overview on Droncit for Cats and Dogs.

Dosage and Usage

Follow the official label and your veterinarian’s protocol. The typical high-level schedule for a Canine DAPPv vaccine is:

• Puppy series: start at 6 weeks of age or older.
• Administer 1 mL per dose, with boosters every 3 to 4 weeks until at least 16 weeks of age.
• Dogs 16 weeks or older with unknown vaccine history: give two doses 3 to 4 weeks apart.
• Revaccinate one year later, then continue at intervals directed by the label and local policy.

Reconstitute the freeze-dried vaccine with the supplied diluent just before use. Gently swirl to mix and use promptly. Administer at the recommended injection site per label guidance. Do not mix with other vaccines or products in the same syringe unless the label specifically permits.

Strengths and Forms

Nobivac Canine 1-DAPPv is supplied as single-dose vials of freeze-dried vaccine with matching diluent. Common presentations include:

• 1 mL single-dose vials with diluent (Nobivac 1 DAPPv single dose)
• Multi-unit cartons such as 25 x 1 dose (Nobivac Canine 1-DAPPv 25×1 dose)

Availability, pack sizes, and labeling can vary by batch and supplier.

Missed Dose and Timing

If a scheduled dose is missed, consult a veterinarian. In general, complete the primary series as soon as practical and maintain the recommended minimum intervals between doses. Do not shorten intervals below label guidance. For adult dogs overdue for a booster, a veterinarian may advise a restart or catch-up plan based on risk and history.

Storage and Travel Basics

Store unopened vaccine and diluent refrigerated at 2°C to 7°C (36°F to 45°F). Do not freeze. Protect from light. After reconstitution, use the dose promptly; do not save reconstituted vaccine for later use. If you are transporting doses, keep them in an insulated container with cool packs to maintain the cold chain.

When your order arrives, place it in the refrigerator right away. If you have questions about storage at home or during clinic transport, ask the dispensing pharmacist or your veterinary team.

Benefits

The Nobivac DAPPv vaccine supports protection against four serious viral diseases in dogs. Key benefits include:

• Core coverage: distemper, adenovirus, parainfluenza, and parvovirus in one dose.
• Single-dose packaging helps maintain dose integrity and reduces wastage.
• Flexible incorporation into standard puppy and adult DAPPv schedules.
• From Merck Animal Health, a well-established veterinary vaccine manufacturer.

Using a consistent schedule improves the likelihood of a strong and durable immune response. Many clinics consider DAPPv the foundation of a dog’s preventive care plan.

Side Effects and Safety

Most dogs tolerate vaccination well. Common, usually mild effects can include:

• Brief soreness or swelling at the injection site
• Mild fever, tiredness, or reduced appetite
• Transient nasal discharge or sneezing

Serious reactions are uncommon but can include allergic or anaphylactic responses, hives, facial swelling, vomiting, collapse, or persistent injection-site lumps. Seek immediate veterinary care if severe signs appear. Vaccinate only healthy dogs. Report suspected adverse events to your veterinarian.

Drug Interactions and Cautions

Immunosuppressive drugs, high-dose corticosteroids, and certain immunomodulators may reduce vaccine responsiveness. Discuss timing if a dog is receiving these therapies. For background on one common immunomodulator, see Apoquel for Dogs.

Do not mix this vaccine in the same syringe with other products unless allowed by the label. Give different vaccines at separate sites. Maternal antibodies can interfere with puppy responses, which is why the series includes multiple doses through 16 weeks. Routine antibiotic use generally does not prevent vaccination, but clinical judgment is needed; you can review basics in Cephalexin for Dogs and Cats.

Vaccinate only healthy dogs. Defer use in animals with fever or systemic illness until cleared by a veterinarian.

What to Expect Over Time

Mild, short-lived effects can occur within a day or two after a dose. Protective immunity develops over time with the primary series and subsequent boosters. Adult boosters help maintain protective antibody levels. As dogs age, ongoing preventive care remains important; see helpful context in Arthritis in Dogs and Cats.

Compare With Alternatives

Alternatives within the same category include product lines you may see in practice or retail. Two related options available here are Nobivac® Canine EDGE 1 DAPPv and Nobivac® Puppy DPV. A veterinarian can help choose an appropriate schedule, especially for young puppies or high-risk environments.

Pricing and Access

Compare the Nobivac Canine 1-DAPPv price under Canadian pricing and US shipping. Buy Nobivac Canine 1-DAPPv online and view current cost options, including single-dose and multi-dose cartons. You can order Nobivac Canine 1-DAPPv for sale from Canada with US delivery from Canada. For broader options, browse our Pet Medications.

To see current deals, visit our promotions page. Checkout is simple, and you can complete your order with secure payment. We maintain prompt, express, cold-chain shipping for temperature-sensitive vaccines.

Availability and Substitutions

Supply can vary. If a particular pack size is unavailable, a veterinarian may recommend an alternative DAPPv vaccine or a puppy DPV series to complete protection. Some clinics also use combinations that include leptospirosis components, such as a DAPPv L4 vaccine for dogs, when appropriate. Follow professional guidance; do not delay core protection for puppies without a plan.

Patient Suitability and Cost Saving Tips

Suitable patients are healthy dogs at least 6 weeks of age. Dogs with acute illness or a history of severe vaccine reactions need individual assessment. Discuss timing in pregnant or lactating bitches. Dogs on immunosuppressive therapy may require adjusted scheduling.

Cost-saving ideas:

• Order enough doses to complete a planned series when appropriate.
• Choose single-dose packs to avoid wastage in small households.
• Set refill reminders for upcoming boosters and future series.
• Group vaccine orders with other pet supplies to streamline shipping.

For chronic disease management alongside vaccination, practical guidance such as our primer on canine metabolic care can help plan visits.

Questions to Ask Your Clinician

• What DAPPv schedule fits this dog’s age, risk, and lifestyle?
• Should we use a DAPPv puppy series or begin with a different protocol?
• When is the next booster due after the initial series?
• Are there reasons to delay vaccination today?
• Can this vaccine be given with other core or lifestyle vaccines?
• What signs after vaccination should prompt a clinic call?

Authoritative Sources

• Merck Animal Health – Nobivac Vaccines for Dogs
• USDA APHIS – Veterinary Biologics Product Labels
• CFIA – Licensed Veterinary Biologics (Canada)

Ready to proceed? Place your order for US delivery from Canada with prompt, express, cold-chain shipping.