Nobivac® Canine Edge 1-DAPPv Vaccine for Dogs

What Nobivac® Is and How It Works

Nobivac® Canine Edge 1-DAPPv is a combination vaccine for dogs. It helps protect against canine distemper, adenovirus type 2 (hepatitis), parainfluenza, and parvovirus. This page helps order authentic vaccine from Canada with US delivery from Canada and Canadian pricing, even for owners paying without insurance. Every CanadianInsulin order is prescription-checked with your clinic and dispensed by a licensed Canadian pharmacy.

The canine DAPPv vaccine works by presenting viral antigens to the immune system. Dogs develop antibodies and cellular responses that reduce the risk of severe disease. The Edge presentation supports efficient handling in clinic settings. Follow the official label and the veterinarian’s guidance for timing and use.

Who Nobivac Is For

This vaccine is indicated for healthy dogs, including puppies, as part of a core immunization plan. It supports protection for dogs at risk of exposure to distemper, adenovirus, parainfluenza, and parvovirus. Veterinarians commonly include it in routine puppy series and adult boosters.

Avoid vaccinating dogs that are ill, febrile, or showing signs of active disease. Do not vaccinate pregnant animals unless a veterinarian specifically advises it per label allowances. Dogs with prior hypersensitivity to vaccine components should not receive this product.

Dosage and Usage

Use this product according to the official label. The schedule below reflects widely published DAPPv guidance.

• Puppies: begin the series as early as 6 weeks of age. Give boosters every 2 to 4 weeks until at least 16 weeks of age.
• Unvaccinated adults or dogs with unknown history: administer two doses 2 to 4 weeks apart.
• Booster: give a booster approximately one year after the initial series. Ongoing boosters are then given as directed by the veterinarian.
• Route: administer by subcutaneous injection. Reconstitute the lyophilized vaccine with the supplied sterile diluent immediately before use.
• Use a new sterile needle and syringe for each dog. Do not split a single-dose vial between dogs.

Record the lot number and expiration date in the medical record. Observe the dog briefly after vaccination per clinic protocol. Local guidelines, travel, shelter exposure, or kennel risk can change the plan.

Strengths and Forms

• Single-dose vials with lyophilized vaccine and sterile diluent.
• Multi-dose clinic presentations such as 10-dose vials with matched diluent.
• Packaging and configurations may differ between suppliers and lots.

Availability can vary. Presentation names and counts may differ in Canada versus the US market.

Missed Dose and Timing

For puppies, keep boosters 2 to 4 weeks apart when possible. If a dose is missed, the veterinarian may advise resuming the series or repeating a dose. Adults who miss a booster may need a single catch-up dose or a re-start based on risk and time since last vaccination. Avoid giving doses closer together than directed on the label.

Storage and Travel Basics

Store unopened vials refrigerated at 2 to 8 degrees Celsius. Protect from light. Do not freeze. Keep out of reach of children and pets.

After reconstitution, use the vaccine promptly as directed on the label. Discard any unused mixed vaccine safely. Do not introduce chemical disinfectants into the vial or syringe, as this can inactivate components.

When traveling, use an insulated container with frozen gel packs. Keep vials upright and insulated from direct contact with ice packs. Monitor temperatures during transit when possible. CanadianInsulin uses prompt, express, cold-chain shipping for temperature-sensitive products.

Benefits

• Core protection against four major canine viruses in one injection.
• Supports routine puppy series and adult revaccination programs.
• Combination dosing can reduce separate injections and clinic visits.
• Available with Canadian pricing and US shipping from Canada.
• Fits into widely used canine DAPPv vaccine schedules.

Side Effects and Safety

• Temporary soreness or swelling at the injection site.
• Mild fever, reduced activity, or decreased appetite for a day or two.
• Brief nasal discharge or sneezing may occur with respiratory antigens.
• A small, localized lump at the injection site that resolves over time.

Serious reactions are uncommon but possible. Hypersensitivity reactions, including facial swelling, hives, vomiting, collapse, or breathing difficulty, require immediate veterinary attention. Report unexpected or severe events to the clinic. Dogs with prior vaccine reactions may need a modified plan or pre-medication under veterinary care.

Drug Interactions and Cautions

• Immunosuppressive drugs, high-dose corticosteroids, or chemotherapy can reduce vaccine response.
• Maternal antibodies in puppies may interfere early, which is why a series is needed.
• Do not mix this vaccine in the same syringe with other products unless the label allows it.
• Vaccinate only healthy animals. Postpone if the dog is ill or recovering from illness.
• Use sterile technique. Do not use disinfectants inside the vial or syringe.

What to Expect Over Time

After the initial series, the veterinarian sets a booster schedule to maintain protection. Many clinics provide a one-year booster after the puppy series, then continue based on label directions and local risk. Mild post-vaccination tiredness or soreness can occur briefly. Most dogs resume normal activity soon after.

Compare With Alternatives

Nobivac Canine Edge 1-DAPPv is one option within the DAPPv category. The non-Edge presentation, often listed as Nobivac Canine 1-DAPPv, is another product used by clinics. For very young dogs, a two-valent distemper-parvovirus product such as Nobivac® Puppy Dpv may be considered early in the series under veterinary guidance. Some clinics also add a leptospirosis component during or after DAPPv; see Nobivac® Canine Lepto 4 for dogs at risk.

Pricing and Access

Check the current Nobivac Canine Edge 1-DAPPv price on this page before ordering. Many clinics and owners buy Nobivac Canine Edge DAPPv online from Canada to access Canadian pricing with US shipping. Self-pay customers can compare costs across presentations and vial sizes. For category browsing, see Pet Medications. If looking for limited-time offers, visit Promotions for any sitewide savings information.

Availability and Substitutions

Supply varies by season and lot. If a specific presentation is unavailable, a veterinarian may recommend a comparable DAPPv product or adjust the schedule. CanadianInsulin lists available options and vial sizes when in stock. Restock dates are not guaranteed.

Patient Suitability and Cost Saving Tips

This vaccine suits healthy dogs that need core protection as part of a routine plan. Dogs with chronic conditions, a history of severe reactions, or pregnancy status need individualized decisions. For households with multiple dogs or for clinics, multi-dose vials can lower per-dose cost when used with proper sterile technique. Ordering ahead of scheduled boosters can reduce shipping frequency. Set calendar reminders to stay on schedule.

For more dog health reading, see Hyperglycemia In Dogs, Hypoglycemia Dogs, and Feline And Canine Diabetes.

Questions to Ask Your Clinician

• What puppy series timing and intervals best fit this dog’s risk?
• Should parainfluenza be covered annually in this region?
• Is a leptospirosis vaccine recommended with DAPPv for this dog?
• How should reactions be managed if they occur after vaccination?
• What booster schedule do you recommend after the first year?
• Can titer testing help assess protection for certain components?

Authoritative Sources

• Merck Animal Health US
• Merck Animal Health Canada
• USDA Veterinary Biologics

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