Nobivac® Canine Lepto 4 Vaccine for Dogs

Order Nobivac® Canine Lepto 4 vaccine from Canada with US delivery. This veterinary vaccine helps protect dogs against leptospirosis caused by four common serovars. Many owners purchase at a cash price without insurance, taking advantage of Canadian pricing and prompt, express, cold-chain shipping.

What Nobivac® Is and How It Works

Nobivac® Canine Lepto 4 is an inactivated bacterial vaccine (bacterin) for dogs. It contains antigens from four Leptospira serovars to help stimulate protective immunity. From Canada, it ships to the US and arrives under controlled temperatures, supporting product integrity from origin to your veterinarian’s clinic.

At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.

Leptospirosis is a zoonotic bacterial disease spread by wildlife and contaminated water or soil. Vaccination helps reduce the risk of illness and can reduce urinary shedding of the organism in vaccinated dogs. This vaccine is typically given as part of an individualized immunization plan determined by a veterinarian. For broader pet health needs, explore our Pet Medications.

Administration and scheduling should follow the product label and your veterinarian’s guidance. Local regulations may require veterinary administration. Do not use in other species and do not self-inject without veterinary direction.

Who Nobivac Is For

This vaccine is for healthy dogs, generally 8 weeks of age or older, as directed on the label. It is often recommended for dogs with outdoor exposure, access to standing water, or wildlife contact, and for dogs living in regions where leptospirosis is prevalent.

Dogs that are ill, severely debilitated, or have a history of vaccine hypersensitivity should be evaluated by a veterinarian before vaccination. Safety in breeding, pregnant, or lactating dogs may not be established on all labels, so clinical judgment is important.

Dosage and Usage

Follow the official label and your veterinarian’s instructions. A common schedule includes:

• Primary series: 2 doses, given 2 to 4 weeks apart.
• Dose volume: typically 1 mL per dose for dogs, as labeled.
• Route: administered by a veterinarian per label directions.
• Booster: annual revaccination is commonly recommended to maintain protection.

Use the vaccine as supplied. Do not mix with other products in the same syringe unless the label specifically allows. If other vaccines are given at the same visit, your veterinarian may use separate syringes and injection sites.

Strengths and Forms

Availability may vary by clinic and season. Common presentations include:

• Single-dose vials (1 dose; often referenced as Nobivac Lepto 4 1 dose).
• 10-dose vial (bulk 10 dose vial for clinical use).
• 25 x 1 dose pack (25 single-dose vials for larger vaccination needs).

Labeling and packaging differ by market. Your veterinarian will select the appropriate presentation for your dog’s plan.

Missed Dose and Timing

If the second dose in the series is delayed, schedule the missed dose as soon as practical. The veterinarian may restart or continue the series based on the interval and the product label. Do not double doses. Dogs should be clinically healthy on the day of vaccination; reschedule if the dog is acutely unwell.

Storage and Travel Basics

Store Nobivac Canine Lepto 4 in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light and keep in the original carton until use. Use promptly after opening or reconstitution as directed on the label. Keep out of reach of children and animals.

If you are transporting vaccine to a clinic appointment, keep it upright and chilled in an insulated container with ice packs. For shipments, CanadianInsulin uses cold-chain handling appropriate for temperature-sensitive products.

Benefits

Nobivac Canine Lepto 4 offers broad leptospirosis coverage aligned with label claims. It helps protect against disease associated with four key Leptospira serovars. For many dogs, this vaccine can be combined with core or lifestyle vaccines as part of a tailored plan managed by a veterinarian.

• Four-serovar coverage commonly used in canine practice.
• Helps reduce the risk of leptospiral disease and urinary shedding in vaccinated dogs.
• Single- and multi-dose options suitable for different clinic needs.
• Backed by a well-established Nobivac portfolio from Merck Animal Health.

Side Effects and Safety

• Temporary lethargy or decreased activity
• Mild fever
• Reduced appetite
• Injection-site soreness, swelling, or a small lump
• Transient vomiting or diarrhea

Serious reactions are uncommon but can include allergic or anaphylactoid responses. Hives, facial swelling, breathing difficulty, collapse, or severe vomiting warrant urgent veterinary attention. Report any suspected adverse event to your veterinarian. Dogs with prior vaccine reactions may need pre-vaccination plans or alternative strategies decided by the clinician.

Drug Interactions and Cautions

Immunosuppressive therapies, including high-dose corticosteroids or certain immune-modulating drugs, may blunt vaccine response. Discuss all medicines and supplements the dog receives before vaccination. Do not mix this product with other vaccines unless the label states compatibility. Give at separate sites when multiple vaccines are administered at one visit.

Use caution in dogs with chronic illness. Vaccination is generally delayed in dogs with acute fever or active infection until they recover. For background on allergy therapies that may affect immune responses, see Apoquel For Dogs. For information on antibiotics commonly discussed in canine care, review Baytril Antibiotic. Always defer to your veterinarian for case-specific decisions.

What to Expect Over Time

Most dogs are comfortable after vaccination and resume normal activity quickly. Mild tiredness or low-grade fever can occur for a short period. Protection is built over the primary series and maintained with boosters as advised by the veterinarian.

Risk exposure can change with travel, boarding, or new outdoor habits. The clinician may revisit the plan at annual visits or if lifestyle changes. For dogs managing other conditions, such as endocrine disease, see our overview on Canine Diabetes Treatment for species-relevant education.

Compare With Alternatives

Leptospirosis protection can be paired with other canine vaccines to build a complete plan. Your veterinarian may schedule Nobivac Canine Lepto 4 with core vaccines for distemper and parvovirus. For example, clinics often use Nobivac® Canine 1 Dappv for core viral coverage. For very young dogs, early core protection may include Nobivac® Puppy Dpv as part of a staged protocol.

These products serve different purposes and are not substitutes for leptospirosis coverage. The veterinarian will align timing and selection with age, risk, and regional guidance.

Pricing and Access

Buy Nobivac Lepto 4 vaccine online with US shipping from Canada. View the current Nobivac Lepto 4 price and compare the cost of single-dose versus bulk 10 dose vial or 25 x 1 dose pack. Orders are US delivery from Canada with temperature control for biologics.

Canadian pricing can offer savings for self-pay pet families. Add the product to cart to see options, confirm availability, and complete encrypted checkout after we verify the prescription with your clinic.

Availability and Substitutions

Supply can vary. If Nobivac Canine Lepto 4 is unavailable, a veterinarian may recommend a suitable alternative leptospirosis vaccine or a different Nobivac configuration that aligns with the dog’s schedule. Substitutions are determined by the prescriber and local regulations.

Patient Suitability and Cost Saving Tips

Good candidates are healthy dogs at least 8 weeks old with lifestyle or regional risk for leptospirosis. Dogs with a history of vaccine reactions, acute illness, or certain medical conditions require individualized plans. The veterinarian will weigh risks and benefits for each dog.

• Choose single-dose vials for individual dogs or small households.
• Use bulk 10 dose vial or 25 x 1 dose packs for kennels, rescues, or multi-dog homes under veterinary oversight.
• Coordinate orders with other pet needs to reduce extra shipments when possible.
• Enable refill or reminder tools so boosters are planned in advance.
• Keep vaccines refrigerated during transport to the clinic to protect quality.

Questions to Ask Your Clinician

• Is my dog’s lifestyle and region a match for leptospirosis vaccination?
• What is the recommended timing for the second dose and annual boosters?
• Can this vaccine be given at the same visit as core or lifestyle vaccines?
• What mild side effects are expected, and when should urgent care be sought?
• How do existing conditions or medicines affect vaccine response?
• Which package size (single dose, 10 dose vial, 25 x 1 dose) fits our needs?
• What documentation will be provided for boarding, travel, or training programs?

Authoritative Sources

• Merck Animal Health USA
• USDA Center for Veterinary Biologics
• Merck Animal Health Canada

Start your order for US delivery from Canada with prompt, express, cold-chain shipping.