Please note: a valid prescription is required for all prescription medication.
Nobivac® Puppy-DPv is a canine vaccine that helps protect puppies against canine distemper and canine parvovirus. CanadianInsulin provides Canadian pricing with US delivery from Canada. You can buy Nobivac Puppy-DPv online and have it shipped from Canada to the US, even if you pay without insurance.
At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.
Made by Merck Animal Health, the Nobivac Puppy-DPv vaccine is designed for the core protection of young dogs. This Puppy DPv vaccine contains modified live virus antigens and a sterile diluent, packaged for veterinary use and administered under professional supervision.
What Nobivac® Is and How It Works
Nobivac Puppy-DPv is a modified live virus combination that targets two serious canine pathogens: canine distemper virus and canine parvovirus. After injection, the vaccine stimulates the immune system to produce antibodies and cellular responses that help protect puppies from these highly contagious diseases. This DPv formulation focuses on early, essential coverage while puppies build immunity through a series of veterinary visits.
The Nobivac DPv vaccine comes as a freeze-dried cake supplied with a sterile diluent. A veterinary professional reconstitutes the dose and administers it subcutaneously. Because maternal antibodies can block vaccine response in young dogs, veterinarians commonly give a series of doses at set intervals to ensure protection as maternal antibody levels fall.
Nobivac Puppy-DPv is part of core canine immunization protocols recommended by many veterinarians. Your clinic will decide the sequence and timing in relation to other vaccines. Do not inject into sick or febrile animals, and do not mix this vaccine in the same syringe with other products unless the label specifically allows it.
Who Nobivac® Is For
This vaccine is intended for healthy puppies and dogs, as determined by a veterinarian. It is used to help prevent disease caused by canine distemper virus and canine parvovirus. Puppies typically receive a series of doses during their initial vaccination period, followed by boosters as recommended by the clinic. Nobivac Puppy-DPv is appropriate when focused coverage for distemper and parvovirus is desired as part of a comprehensive puppy plan.
Veterinarians generally avoid vaccinating animals that are ill, febrile, or under significant stress, since those conditions can reduce response. Dogs with a history of severe vaccine reactions, those on immune-modifying therapies, or pregnant animals may require special consideration or a different plan. Always have a veterinarian assess health status before vaccination.
Dosage and Usage
Veterinarians administer Nobivac Puppy-DPv by subcutaneous injection after reconstituting the lyophilized vaccine with its supplied diluent. Clinics typically start the puppy series during early veterinary visits and continue every 3 to 4 weeks until the series is complete, as guided by age, risk, and local recommendations. A booster is commonly given after the initial series, followed by further boosters at intervals determined by the clinic and local regulations.
Use aseptic technique. Reconstitute immediately before use and administer the full dose once mixed. Do not combine with other vaccines or medications in the same syringe unless the label states compatibility. Veterinarians may administer other indicated vaccines during the same visit at separate sites, consistent with professional guidance.
Strengths and Forms
Nobivac Puppy-DPv is supplied as:
- Single-dose vials (Nobivac Puppy-DPv single dose or 1 dose)
 - Clinic packs such as 25 x 1 dose presentations
 
Packaging may vary by supplier and inventory. Availability of Nobivac Puppy-DPv 25 x 1 dose can help clinics and shelters manage larger vaccination programs efficiently. Single-dose vials are convenient for individual patients and small practices. All presentations include the lyophilized vaccine and sterile diluent.
Missed Dose and Timing
If a puppy misses a scheduled vaccination, the veterinarian will advise when to continue the series. In many cases, the series resumes as soon as practical to maintain momentum toward protection. The timing of doses can affect the immune response, especially while maternal antibodies wane. Keep clear records of vaccination dates and bring them to each visit so your clinic can plan the next step.
Storage and Travel Basics
Store Nobivac Puppy-DPv in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Reconstitute only when ready to vaccinate and use the dose promptly. Keep all vaccines and medical supplies out of reach of children and animals.
When traveling, keep the vaccine cold in an insulated container with ice packs. Avoid direct sun and prolonged warm exposure. If the cold chain is uncertain, consult your veterinarian before use. CanadianInsulin uses cold-chain shipping to help maintain product integrity during transit.
Benefits
Nobivac Puppy-DPv helps protect against two life-threatening diseases that are common worldwide. Distemper can cause respiratory, neurologic, and systemic illness. Parvovirus can lead to severe gastrointestinal disease and dehydration. Early protection is important during the puppy stage, and this DPv option focuses on those core risks. Single-dose vials simplify handling in clinic settings. Established manufacturing quality from Merck Animal Health supports consistent performance when used as directed.
Side Effects and Safety
Most vaccinated dogs tolerate the dose well. Temporary and mild reactions can occur after vaccination. Common effects include:
- Brief soreness at the injection site
 - Mild swelling or a small, firm bump at the site
 - Low-grade fever
 - Tiredness or reduced activity
 - Decreased appetite
 - Transient digestive upset
 
Serious reactions are uncommon but possible. Rare events can include facial swelling, hives, vomiting, trouble breathing, collapse, or severe allergic reactions. Veterinary care is required for any severe or fast-worsening signs. As with other vaccines, immune-mediated responses are rare but have been reported. Do not vaccinate animals that are ill, severely stressed, or known to have had a serious reaction to a previous vaccine unless a veterinarian recommends a specific plan.
Drug Interactions and Cautions
Immunosuppressive therapies can reduce vaccine efficacy. Corticosteroids, certain cytotoxic drugs, and some immune-modulating agents may blunt the immune response. If a dog is managed for allergic skin disease or pruritus with therapies such as oclacitinib, discuss timing with the veterinarian. For background on a common option, see Apoquel For Dogs. Do not give Nobivac Puppy-DPv to sick, febrile, or pregnant animals unless directed by a veterinarian. Maternal antibodies in young puppies can interfere with immunization, which is why a series is recommended. Do not mix the vaccine with other products in the same syringe.
What to Expect Over Time
Protection builds with the puppy series and the follow-up booster. The first dose begins priming the immune system, and additional doses improve the response. Puppies remain at risk while the series is in progress. Veterinarians often advise limiting exposure to unfamiliar dogs and high-risk environments until the series is complete. Routine parasite control and general wellness care also support healthy development. Deworming is a separate need; for more information on a common tapeworm treatment, see Droncit For Dogs.
Compare With Alternatives
Some clinics choose broader combination vaccines during the puppy series. An option that adds adenovirus and parainfluenza coverage is Nobivac® Canine 1 DAPPv. In areas where leptospirosis risk is significant, veterinarians often add a leptospirosis component such as Nobivac® Canine Lepto 4. Some practices also consider Nobivac Canine Edge 1 DAPPv based on clinic protocols. Your veterinarian will recommend the best schedule for local risks and the puppy’s age.
Pricing and Access
See the current Nobivac Puppy-DPv price on this page. Canadian pricing may offer meaningful cash-pay value compared with typical US cash price. You can order Nobivac Puppy-DPv online with US shipping from Canada. Many clinics and shelters select the Nobivac Puppy-DPv 25 x 1 dose pack for efficiency. Individual pet owners often prefer the Nobivac Puppy-DPv single dose size. If you pay cash or out of pocket, you can still access transparent pricing before checkout. For other pet supplies and treatments, browse our Pet Medications.
Availability and Substitutions
Inventory can vary by presentation and season. If a requested presentation is unavailable, a veterinarian may recommend an alternative schedule or product that provides comparable coverage. We cannot guarantee restock dates, but we display current availability and package sizes as they change.
Patient Suitability and Cost Saving Tips
Nobivac Puppy-DPv is intended for healthy puppies and dogs as assessed by a veterinarian. Animals with uncontrolled illness, fever, or recent severe vaccine reactions may not be candidates. Dogs treated for endocrine disease or metabolic issues should be stabilized before vaccination; for context on one condition, see Hyperglycemia In Dogs. Pain or inflammation medications can be part of other care plans; read more in Deramaxx For Dogs.
To save on costs, clinics often order multi-dose clinic packs like 25 x 1 dose when appropriate. Individual owners may choose single-dose vials to match one dog’s needs. Setting reminders for the next dose and the booster helps keep the series on track and avoids re-starts. Keep vaccine receipts and lot numbers with the pet’s records for future reference.
Questions to Ask Your Clinician
- When should the puppy series for distemper and parvovirus begin and end?
 - Which other vaccines are recommended in this region and for this lifestyle?
 - Can other vaccines be given on the same day at separate sites?
 - How should the clinic manage a missed vaccine in the series?
 - What signs after vaccination warrant a same-day call to the clinic?
 - Does current medication or a chronic condition affect vaccine timing?
 - When is the next booster due after the primary series?
 
Authoritative Sources
Start your Nobivac Puppy-DPv order today for US delivery from Canada with prompt, express, cold-chain shipping.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
 - Cold-Packed Products $35.00
 
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
 - Not available for Cold-Packed products
 
Which diseases does Nobivac Puppy-DPv cover?
It helps protect puppies and dogs against canine distemper virus and canine parvovirus. Your veterinarian decides timing within the broader vaccine plan.
Who administers Nobivac Puppy-DPv?
A licensed veterinarian or authorized clinic professional administers a single reconstituted dose by subcutaneous injection, following the official label.
When should puppies start the series?
Clinics typically begin the puppy series early and repeat doses every few weeks until the series is complete. Your veterinarian sets the exact schedule.
Can Nobivac Puppy-DPv be given with other vaccines?
Veterinarians often give other indicated vaccines at the same visit at separate sites. Do not mix products in the same syringe unless the label states compatibility.
What side effects are common after vaccination?
Mild soreness, a small lump at the injection site, low-grade fever, tiredness, and reduced appetite can occur. Severe reactions are rare but require immediate veterinary care.
How is cold shipping handled for my order?
Shipments use insulated packaging and cold packs to maintain the cold chain. Keep the vaccine refrigerated on arrival and do not freeze.
Is Nobivac Puppy-DPv the same as DAPPv?
No. DPv covers distemper and parvovirus. DAPPv adds adenovirus and parainfluenza. Your veterinarian will choose the combination that fits local risks.
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