Celebrex® Capsules for Osteoarthritis and Rheumatoid Arthritis

What Celebrex Is and How It Works

Celebrex® is a prescription nonsteroidal anti-inflammatory drug that helps reduce pain, swelling, and stiffness from several forms of arthritis. This page explains what it is, how to use it safely, and how to access it with US delivery from Canada. For context on celebrex price without insurance, see the Pricing and Access section below.

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The active ingredient is celecoxib, a COX-2 selective inhibitor. It limits the body’s production of prostaglandins that drive inflammation and pain. This selectivity may reduce stomach irritation compared with some older NSAIDs, but serious gastrointestinal and cardiovascular risks can still occur. Use the lowest effective dose for the shortest duration that meets your treatment goals.

For additional background on celecoxib and pain management concepts, you can read our Comprehensive Guide.

Who It’s For

This medicine is indicated for symptomatic relief of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also used for acute pain and primary dysmenorrhea in adults. Learn more about these conditions in our categories for Osteoarthritis, Rheumatoid Arthritis, and Ankylosing Spondylitis.

Do not use if you have had an allergic reaction to celecoxib or other sulfonamide medicines. Avoid use right before or after coronary artery bypass graft surgery. People with a history of severe asthma after aspirin or other NSAIDs should not take this treatment. Discuss risk factors such as prior ulcers, kidney problems, uncontrolled hypertension, or heart disease with your prescriber.

Dosage and Usage

Your prescriber will set your schedule based on your diagnosis and response. Many patients take it once or twice daily. Swallow capsules whole with water. You may take it with or without food; food can help if your stomach is sensitive.

If you cannot swallow capsules, ask your clinician about opening the capsule and mixing the contents with a small amount of applesauce for immediate use. Do not save mixtures for later. Do not use more than directed or combine with other NSAIDs unless your clinician has advised it. Alcohol can increase stomach irritation; limit or avoid it while using this treatment.

Because pain levels and flares vary, your prescriber may suggest using the lowest effective dose for routine control, and reserving additional analgesics only when needed. Follow the official label and your clinician’s instructions.

Strengths and Forms

This treatment is supplied as oral capsules. Multiple strengths are available to tailor therapy across different conditions and body sizes, including a 200 mg option. Availability may vary by pharmacy and region.

When budgeting, some patients compare celecoxib 200 mg price with lower-dose options to select a practical fill. Your prescriber will determine the appropriate strength; use price comparisons only after a dose is set.

Missed Dose and Timing

If you miss a dose and it is not close to the next one, take it when remembered. If your next dose is due soon, skip the missed dose and resume your regular schedule. Do not double doses to catch up. If you experience frequent forgetfulness, ask your clinician about reminders or once-daily timing.

Storage and Travel Basics

Store capsules at room temperature in a dry place, away from direct light and moisture. Keep the bottle closed and out of reach of children and pets. Do not store in a bathroom or near sinks. Use the original container during travel to keep labeling attached.

When flying, carry your medication and prescription in your hand luggage. Security officers may request to see the pharmacy label. If your clinician advises periodic travel supplies, request refills early so you do not run out. Pharmacies use temperature-controlled handling when required.

Benefits

As a COX-2 selective NSAID, this medicine can relieve joint pain and stiffness so you can move more comfortably. It may be used for chronic joint conditions or for short-term flares and acute pain, as directed. Many patients find regular dosing supports daily function when combined with exercise and physical therapy.

Side Effects and Safety

• Stomach pain or indigestion
• Diarrhea or gas
• Headache or dizziness
• Upper respiratory symptoms
• Swelling in legs or feet
• Nausea or heartburn

Serious effects are less common but can include heart attack, stroke, gastrointestinal bleeding or ulcers, kidney problems, severe skin reactions, and allergic reactions. Stop the medicine and seek immediate care for chest pain, shortness of breath, black stools, vomiting blood, sudden weakness on one side, severe rash, or facial or throat swelling. This drug, like other NSAIDs, may raise blood pressure and fluid retention risk. It is generally not recommended late in pregnancy. Ask your clinician before using it while pregnant or breastfeeding.

Drug Interactions and Cautions

Tell your prescriber about all drugs and supplements you use. Combining with other NSAIDs or aspirin can raise bleeding or stomach risk. Anticoagulants and antiplatelet agents can increase bleeding risk. Corticosteroids and SSRIs or SNRIs may further increase gastrointestinal risk. ACE inhibitors, ARBs, and diuretics can reduce kidney function when used with NSAIDs, especially in dehydration.

Use caution with lithium, methotrexate, and certain blood pressure and heart medicines. Strong CYP2C9 inhibitors like fluconazole can raise celecoxib levels; inducers can lower them. Limit alcohol if your stomach is sensitive. Do not start or stop any medicine without medical guidance.

What to Expect Over Time

Many patients notice pain relief after treatment begins, but individual responses vary. Your clinician may adjust your schedule to balance relief and tolerability. If swelling or pain persists, your plan may include non-drug measures such as physical therapy, weight management, and joint protection. Budget questions sometimes arise; if you are exploring celecoxib price comparisons, discuss practical fill sizes after your dose is established.

Compare With Alternatives

For autoimmune arthritis where NSAIDs alone are insufficient, clinicians may escalate therapy to disease-modifying options. Two established biologics used for rheumatoid arthritis and ankylosing spondylitis are Humira and Enbrel Syringe. These medicines act on immune pathways and are prescribed when symptom control and joint protection need intensification. Your clinician will decide if these are appropriate for your diagnosis and history.

Pricing and Access

We highlight transparent options so you can review celebrex price and decide on a suitable fill. Factors that affect your out-of-pocket expense include strength, quantity per bottle, and brand versus generic. Some patients compare cash-pay totals across pharmacies to estimate potential savings. For broader options beyond one drug, explore our Pain and Inflammation category. We provide ordering support with US shipping from Canada.

If you look for promotions, check our current notices on Promotions. Final costs depend on your prescription, selected product, and pharmacy inventory.

Availability and Substitutions

Generic celecoxib is widely used and may offer a lower net spend than the brand. If a particular bottle size is unavailable, your prescriber may recommend a therapeutically equivalent option. Talk with your clinician and pharmacist about celebrex generic price when considering substitution.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults needing ongoing NSAID therapy who do not tolerate nonselective NSAIDs or who require a once- or twice-daily regimen. It may not suit patients with active gastrointestinal bleeding, severe kidney disease, or recent coronary bypass surgery. If you have sulfonamide allergy, discuss risks before use.

For budgeting, ask your clinician about generic celecoxib when appropriate. Consider multi-month fills if your plan is stable, as per prescriber guidance. Set refill reminders so you do not run out. If you compare celecoxib generic price between pharmacies, align comparisons to the same strength and quantity. Discuss whether combining orders with other household prescriptions reduces overall dispensing fees. For education around joint care, see our article on Bone and Joint Tips.

Questions to Ask Your Clinician

• Is this NSAID appropriate for my condition and risk profile
• What schedule should I follow to minimize side effects
• How long should I try this therapy before reassessing
• Which warning signs mean I should stop and seek care
• Can I use it with acetaminophen for added pain control
• Which other medicines or supplements should I avoid
• Would generic substitution be reasonable for me

Authoritative Sources

For full prescribing details reviewed by regulators, see the FDA label on FDA DailyMed. The manufacturer’s current prescribing information is available on Pfizer Prescribing Information. Canadian product data can be found via Health Canada DPD.

Ready to proceed? You can buy celebrex online with prompt, express, temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.