Xarelto® Tablets for Atrial Fibrillation

Xarelto is a prescription anticoagulant that helps lower the risk of harmful blood clots. These rivaroxaban tablets are used to prevent stroke in atrial fibrillation and to treat or prevent deep vein thrombosis and pulmonary embolism. We offer US delivery from Canada, helping you compare options without insurance.

What Xarelto Is and How It Works

Atrial Fibrillation increases the chance of clots that can travel to the brain. Xarelto® belongs to a class called direct factor Xa inhibitors. It blocks factor Xa, a key step in the clotting cascade, which lowers clot formation. As a result, the treatment can reduce the risk of stroke, recurrent DVT, and PE when taken as directed.

Rivaroxaban is absorbed through the gut and then works in the bloodstream. Food can affect absorption for some doses, so follow the label directions. Your clinician may monitor kidney and liver function, especially at baseline.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

Who It’s For

This medicine is indicated to reduce the risk of stroke and systemic embolism in nonvalvular atrial fibrillation. It is also used for treatment of DVT and PE, to reduce recurrence risk after initial therapy, and for DVT prevention after hip or knee replacement. In adults with coronary or peripheral artery disease, it may be used with daily aspirin to lower the risk of major cardiovascular events.

People with active bleeding should not use the treatment. Those with severe hepatic impairment associated with coagulopathy should avoid it. Use caution in serious renal impairment, with a personalized plan from your prescriber. It is not recommended for patients with mechanical heart valves.

Dosage and Usage

Dosing varies by condition. Many patients take the medicine once daily with the evening meal for stroke prevention in atrial fibrillation. For the initial treatment phase of blood clots, a higher-frequency schedule is typically used before stepping down to once daily. For postsurgical clot prevention, a once-daily schedule is commonly used after the procedure.

Take tablets at the same time each day. Swallow whole with water. If you cannot swallow tablets, certain options such as crushing and mixing in applesauce or water may be acceptable according to the official label. Administration through a gastric tube is allowed under specific instructions on the label. Always follow your prescriber’s directions.

Strengths and Forms

Film-coated tablets are commonly available in multiple strengths, including 2.5 mg, 10 mg, 15 mg, and 20 mg. Availability can vary by pharmacy and market.

Missed Dose and Timing

If you miss a once-daily dose, take it as soon as you remember on the same day. Then resume your normal schedule the next day. Do not take two doses on the same day for once-daily regimens.

During phases that use twice-daily dosing, you may be directed to ensure both daily doses are taken within the same day. If you are unsure how to handle a missed dose for your regimen, check the Patient Information and contact your prescriber.

Storage and Travel Basics

Store tablets at room temperature in a dry place. Keep the bottle closed tightly and away from moisture. Use a child-resistant container and store out of reach of children and pets. Do not use tablets that are damaged or show signs of deterioration.

When traveling, carry your medication in your hand luggage with your prescription label. Bring a medication list and your prescriber’s contact information. Allow extra time for security checks. If changing time zones, keep daily timing consistent relative to your home schedule or ask your clinician how to adjust.

Benefits

As a direct oral anticoagulant, the treatment offers fixed dosing regimens and does not require routine INR monitoring. It has fewer food interactions than vitamin K antagonists, which can help with consistent daily use. Once-daily maintenance schedules may support adherence for many patients.

Side Effects and Safety

• Bleeding or easier bruising
• Nosebleeds or gum bleeding
• Fatigue or dizziness
• Headache
• Gastrointestinal upset, nausea, or abdominal discomfort
• Anemia-related symptoms

Serious bleeding can occur and may be life-threatening. Seek urgent medical attention for signs of major bleeding. Spinal or epidural hematomas may occur in patients receiving neuraxial anesthesia or undergoing spinal puncture. Stopping the drug suddenly can increase the risk of clotting; consult your clinician before discontinuing. Read the Medication Guide for full warnings.

Drug Interactions and Cautions

Strong combined inhibitors or inducers of CYP3A4 and P-gp may change medication levels. Examples include certain azole antifungals, macrolide antibiotics, protease inhibitors, rifamycins, some anticonvulsants, and St. John’s wort. Using NSAIDs, antiplatelets, or other anticoagulants can increase bleeding risk. Alcohol may add to bleeding risk as well.

Tell your clinician about past bleeding events, recent surgery, spinal procedures, kidney or liver disease, pregnancy, or plans for dental work. For clot-related conditions, you can learn more about risks and care pathways in our overview of Blood Clots. For broader heart health topics, see our Cardiovascular category.

What to Expect Over Time

Effects are preventive and not felt directly. You should not expect to feel different day to day. Consistent adherence is important for risk reduction. People often ask about xarelto cost, but overall value depends on your indication, dose schedule, and clinical goals determined by your prescriber.

Your care team may periodically assess kidney and liver function and discuss any procedure plans. If you miss doses, have bleeding symptoms, or anticipate surgery, contact your clinician for guidance. Do not stop the medication without medical advice.

Compare With Alternatives

Other direct oral anticoagulants include Eliquis and Pradaxa. Choice depends on your condition, kidney function, dosing preferences, and prescriber judgment. For background on older therapies and clot prevention, see our neutral overview in the Warfarin Guide.

Pricing and Access

Canadian pricing with US shipping from Canada may provide meaningful cash-pay savings versus many local options. If you are comparing xarelto price, review your dose, quantity, and refill schedule before checkout to see the most relevant total. For ideas to reduce out-of-pocket spending on anticoagulants, see our article Save on Apixaban Cost.

You can also check seasonal deals on our Promotions page. Encrypted checkout is supported for a secure transaction.

Availability and Substitutions

Brand and generic availability can vary by strength and market. If you are searching for xarelto generic, note that rivaroxaban versions may be available in some regions. If a specific strength is not in stock, your prescriber may recommend a suitable alternative.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who need long-term anticoagulation for atrial fibrillation or who are managing DVT or PE under a clinician’s care. It may not be appropriate for those with active bleeding, certain liver disease, or mechanical heart valves. Share your full medication list and medical history before starting.

Consider multi-month supplies if appropriate, which can reduce per-fill fees. Set reminders for daily doses and refills. Ask your care team about patient assistance options and whether a pharmacy voucher or xarelto coupon aligns with your plan and local regulations.

Questions to Ask Your Clinician

• My indication and goal: stroke prevention, DVT/PE treatment, or prevention
• Food and timing: take with meals or without
• Bleeding signs: what to watch and when to seek care
• Procedures: how to manage around surgery or dental work
• Interactions: which drugs and supplements to avoid
• Monitoring: kidney or liver tests and visit timing
• Travel: how to keep dosing consistent across time zones

Authoritative Sources

For full prescribing information and patient guides, review these official sources:

• Xarelto Prescribing Information from Janssen
• FDA DailyMed: Rivaroxaban Labeling and Medication Guide
• Health Canada Drug Product Database: Rivaroxaban

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Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.