Addyi® Tablets for Hypoactive Sexual Desire Disorder

Addyi is a prescription medicine for premenopausal women with hypoactive sexual desire disorder. It is taken once each night to modulate brain serotonin activity and may support desire over time. Questions about Addyi cost without insurance are common; this page explains use, safety, and access.

What Addyi Is and How It Works

Addyi® contains flibanserin, a centrally acting serotonergic modulator used for hypoactive sexual desire disorder (HSDD). You can request US delivery from Canada after we receive a valid prescription. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

This medicine acts primarily as a 5‑HT1A receptor agonist and 5‑HT2A receptor antagonist. It may help rebalance serotonin, dopamine, and norepinephrine signals involved in sexual desire. Take it at bedtime to reduce risks of low blood pressure, dizziness, and sleepiness. It is not for on‑demand use.

Who It’s For

This treatment is indicated for premenopausal women diagnosed with acquired, generalized HSDD causing marked distress. It is not approved for men, children, or postmenopausal patients. It should not be used if low desire is primarily due to relationship issues, psychiatric conditions, other medicines, or a medical disorder. Learn more about the condition in our overview of Hypoactive Sexual Desire Disorder.

Dosage and Usage

The usual schedule is one tablet by mouth at bedtime. Use it consistently, not as needed. If there is no meaningful improvement after eight weeks, the prescriber may choose to stop therapy per label guidance.

Alcohol raises the risk of severe hypotension and syncope. If you drink one or two standard alcoholic drinks in the evening, wait at least two hours before the bedtime dose. If you had three or more drinks, skip the dose that night. Do not drink alcohol until the morning after taking the dose. Avoid driving or operating machinery until at least six hours after dosing and until you know how you respond.

Do not use with moderate or strong CYP3A4 inhibitors. These include agents such as ketoconazole, itraconazole, clarithromycin, atazanavir, ritonavir, and fluconazole. Hepatic impairment is a contraindication. Always follow the official label and your prescriber’s direction.

Strengths and Forms

Tablets are commonly supplied in a single strength of 100 mg. Packaging options can influence Flibanserin tablets price and availability across pharmacies. Stock and pack formats may vary by dispensing pharmacy.

Missed Dose and Timing

If you miss the bedtime dose, skip it and take the next dose at the usual time the following night. Do not take it in the morning or double up to make up a dose. Keep a simple reminder to support consistent nighttime dosing.

Storage and Travel Basics

Store tablets at controlled room temperature in the original container, away from moisture and direct light. Keep out of reach of children. When you travel, keep your medicine in your carry‑on, bring your prescription or a copy of the label, and pack only what you need plus a small buffer. If your itinerary changes time zones, keep dosing aligned to your usual bedtime to maintain consistency.

Benefits

When used as directed, this medicine may improve desire and reduce distress linked to HSDD. Taken nightly, it can fit into a routine without daytime dosing. Many patients appreciate having a nonhormonal option. Resources about intimacy and related concerns are available in Navigating Intimacy. Broader women’s health context is discussed in Does Diabetes Affect Fertility.

Side Effects and Safety

• Dizziness or lightheadedness
• Sleepiness or fatigue
• Nausea
• Dry mouth
• Insomnia
• Anxiety
• Abdominal discomfort

Serious risks include severe hypotension and syncope, especially with alcohol or CYP3A4 inhibitors. Driving impairment can occur. Discontinue and seek medical care for fainting, severe dizziness, or persistent sedation. Use in pregnancy or while breastfeeding has not been fully characterized; discuss risks and benefits with your prescriber.

Drug Interactions and Cautions

Avoid moderate or strong CYP3A4 inhibitors (for example, ketoconazole, itraconazole, clarithromycin, atazanavir, ritonavir, nefazodone, and fluconazole). CYP3A4 inducers (such as rifampin, carbamazepine, phenytoin, and St. John’s wort) may lower exposure and reduce effect. Grapefruit or grapefruit juice can raise drug levels and should be avoided.

Concurrent CNS depressants can increase sleepiness and dizziness. Examples include benzodiazepines, opioid analgesics, sedative‑hypnotics, and some centrally acting medicines. Certain antidepressants may contribute to low desire or add sedation; review your regimen with your prescriber. Related references: Escitalopram, Zoloft®, and Fluoxetine. Do not use this treatment with hepatic impairment.

What to Expect Over Time

This therapy is designed for nightly use. Some patients may notice qualitative changes over several weeks of consistent dosing. If distressing symptoms remain unchanged after an adequate trial, the prescriber may determine whether to continue. Keep follow‑up appointments and report daytime sleepiness, dizziness, or syncopal episodes promptly.

Compare With Alternatives

An FDA‑approved alternative for HSDD is bremelanotide injection (Vyleesi), used on an as‑needed schedule before anticipated sexual activity. Nonpharmacologic approaches such as structured sex therapy or counseling may help when psychosocial factors contribute. Explore available options in our Hypoactive Sexual Desire Disorder Hsdd category and read more about the condition in Hypoactive Sexual Desire Disorder.

Pricing and Access

You can review current Flibanserin price on the product page after selecting quantity and providing prescription details. We also list Addyi Canadian pricing so you can compare options available through our partner pharmacies. For potential offers, see promotions. We provide US shipping from Canada with clear checkout steps and encrypted checkout for your protection.

Pricing varies by pack size and dispensing pharmacy. Insurance coverage differs; many patients compare cash‑pay options alongside local pharmacy quotes. Taxes and dispensing fees may apply.

Availability and Substitutions

Brand and any approved generic availability can change. If an item is out of stock, a prescriber may recommend an appropriate alternative. Be cautious with offers for Flibanserin online from unverified sources, as authenticity and safety cannot be guaranteed outside regulated channels.

Patient Suitability and Cost-Saving Tips

This therapy suits premenopausal adults diagnosed with HSDD who can avoid alcohol near dosing and who are not taking prohibited CYP3A4 inhibitors. It is unsuitable for those with liver impairment or persistent hypotension. Discuss your complete medicine list with your prescriber before starting.

To manage expenses, compare multi‑month fills, set refill reminders, and consolidate orders when practical. Ask your prescriber if smaller or larger pack sizes align with your follow‑up schedule. If available in your region, generic flibanserin may reduce costs. We also summarize Flibanserin cost without insurance considerations so you can plan ahead.

Questions to Ask Your Clinician

• Is my low desire consistent with HSDD criteria?
• Could any current medicine be contributing to my symptoms?
• How should I handle alcohol on days I plan to take a dose?
• What signs of low blood pressure should I watch for?
• Which interactions on my list are most concerning?
• When should we reassess whether to continue therapy?
• What nonpharmacologic options might complement this treatment?

Authoritative Sources

For full details, consult these official resources:

• Manufacturer Website
• FDA DailyMed
• Health Canada DPD

Buy Flibanserin with straightforward checkout and Ships from Canada to US; we offer prompt, express shipping with temperature-controlled handling when required. This information is educational and does not replace advice from your healthcare professional.