Antirobe® Capsules for Dogs

What Antirobe Is and How It Works

Antirobe is a veterinary clindamycin antibiotic for common bacterial infections in pets. It is used for dental, skin, and bone infections, and this page explains its forms, uses, and safe handling. Ships from Canada to US and suitable for cash-pay orders, including without insurance.

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This medicine belongs to the lincosamide class. It inhibits bacterial protein synthesis, which helps control susceptible anaerobic and gram-positive organisms. Antirobe® Aquadrops provide a liquid option for precise dosing when capsules are not ideal. The treatment is often selected for periodontal disease in dogs and certain deep tissue infections when culture results or clinical judgment support clindamycin.

For dental and oral conditions, clindamycin has established tissue penetration into periodontal structures. Many clinicians also use it for wounds and abscesses when the likely bacteria fit its spectrum. For additional context on canine oral infections and when antibiotics may be warranted, see our overview of Canine Dental Infection and related guidance on Canine Bone Infection.

Who It’s For

This treatment is intended for dogs and cats with susceptible bacterial infections, including periodontal disease, certain skin infections, and osteomyelitis when appropriate. Veterinarians may prescribe it following examination, culture and susceptibility testing, or established local guidelines.

Use of antirobe for cats is common for dental and soft tissue infections when clindamycin is indicated. Do not use in animals with known hypersensitivity to clindamycin or lincomycin. Use caution in animals with severe kidney or liver disease, in very young or underweight pets, and during pregnancy or lactation as directed by a veterinarian.

Dosage and Usage

Follow your veterinarian’s instructions and the product label exactly. Capsules should be given whole, as directed, and may be offered with a small amount of food unless advised otherwise. Provide access to fresh water after dosing, especially for cats, to reduce the risk of esophageal irritation.

Shake the liquid well and measure each dose with a marked syringe or dropper supplied by your pharmacy. Antirobe liquid can be given directly into the cheek pouch to aid swallowing. If using the oral drops, administer slowly and allow your pet to swallow between small portions.

Complete the full course even if your pet seems improved. Stopping early can allow bacteria to return and may contribute to reduced effectiveness in the future. If your pet vomits or spits out a dose, contact your veterinarian for guidance on whether to repeat that dose.

For background on administering this class in pets and practical tips, review our article on Antirobe Capsules.

Strengths and Forms

This medicine is available as hard gelatin capsules and as an oral liquid (Aquadrops). Antirobe 150 mg is a capsule strength commonly prescribed for larger dogs. A lower capsule strength, such as 25 mg, may be selected for small pets or precise dose adjustments.

Availability can vary by pharmacy and prescription. Your veterinarian will choose the form and strength that best fit your pet’s condition and weight.

Missed Dose and Timing

If you miss a dose, give it when remembered unless it is close to the next scheduled time. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double up doses. Keep a dosing log or set reminders to help maintain consistent administration.

Storage and Travel Basics

Store capsules and liquid in the original container with the cap tightly closed. Keep at room temperature, away from excess heat, moisture, and direct light. Do not freeze the liquid. Protect from curious pets and children by using a secure, elevated storage spot.

For travel, pack the medication in a sealed bag inside your carry-on. Bring your pet’s prescription label or a copy of the prescription in case of questions. Avoid leaving the medicine in a parked car or in direct sun. When crossing borders or flying, allow extra time for screening of veterinary medications and retain documentation.

Benefits

This antibiotic targets bacteria often responsible for periodontal and deep tissue infections in dogs and cats. The capsule form is straightforward for many dogs, while the oral drops help when small or flexible volumes are needed.

Clinicians value its established role in dental infections and certain bone or soft tissue cases. The treatment’s flexible forms can support tailored dosing strategies and easier administration for owners.

For a deeper look at skin conditions where systemic therapy may be used alongside topical care, see our guide to Canine Skin Infection.

Side Effects and Safety

• Gastrointestinal upset: vomiting or soft stools
• Reduced appetite: may be temporary
• Drooling or lip-smacking: more common with liquids
• Lethargy: usually mild and transient

Serious but less common risks can include allergic reactions, severe diarrhea, or difficulty swallowing. In cats, dry pilling can irritate the esophagus; offer water or a small treat afterward when appropriate. Stop the medicine and contact your veterinarian promptly if your pet shows signs of facial swelling, hives, breathing trouble, persistent vomiting, or bloody stools.

For additional background on related antibiotics in pets, you may find our Cephalexin Guide and a broader overview of options in Pet Antibiotics Online useful.

Drug Interactions and Cautions

Clindamycin may interact with erythromycin and chloramphenicol. Concomitant use with neuromuscular blocking agents can increase neuromuscular effects. Discuss all medicines, supplements, and flea or heartworm preventives your pet receives with your veterinarian.

Use carefully in animals with significant kidney or liver impairment. Monitor closely if your pet has a history of gastrointestinal disease. If your pet is pregnant or nursing, your veterinarian will weigh potential benefits and risks before use. For context on alternative classes when culture results suggest different coverage, see our Doxycycline Guide and comparison insights in Azithromycin Reliability.

What to Expect Over Time

Your veterinarian may recommend a defined course with a follow-up assessment if needed. Many pets can show steady progress as the infection responds, although the time course differs by site and severity. Consistent dosing, proper wound or dental care, and completing the course can support better outcomes.

Call your clinic if you notice worsening signs, trouble swallowing, persistent vomiting, or no improvement. Your veterinarian may reassess the diagnosis, check culture results, or adjust therapy if indicated.

Compare With Alternatives

Veterinarians may consider other antibiotics based on culture, site, and prior treatment history. For gram-negative coverage or specific soft tissue infections, Zeniquin can be an option your veterinarian may select. For susceptible skin or urinary pathogens, Cephalexin is a common choice. Amoxicillin-clavulanate combinations, such as Clavamox, are also used when broader beta-lactam coverage is appropriate.

Pricing and Access

Canadian pricing can help many pet owners manage pharmacy costs for prescribed antibiotics. You can review current options and place an order with US shipping from Canada after we receive a valid prescription. For general shopping across categories, explore our selection of Pet Medications.

Savings depend on the prescription and dispensing pharmacy. Review the product page for availability, form, and dispensing details before you order. If your veterinarian recommends a different antibiotic based on culture results, we can often source alternatives within our catalog.

Looking for brand education and comparisons? Browse disease-specific items under Infectious Disease to understand related products your veterinarian may consider.

Availability and Substitutions

Supply can vary by form and strength. If the prescribed item is not available, your veterinarian may recommend a different strength, a liquid in place of capsules, or an alternative antibiotic suited to the infection and culture results. We cannot suggest substitutions without a prescriber’s direction.

Patient Suitability and Cost-Saving Tips

This antibiotic may be suitable for dogs and cats with susceptible infections when chosen by a veterinarian. It is not appropriate for pets allergic to clindamycin or lincomycin, and it should be used cautiously in pets with severe kidney or liver disease.

Ask your veterinarian whether a multi-month fill is appropriate to reduce per-fill fees for chronic or staged treatments. Set refill reminders so you have medication ready if your pet needs a continued course. Discuss whether a liquid or capsule is more practical for your pet’s size and preferences.

Questions to Ask Your Clinician

• Primary target: Which bacteria are suspected or confirmed?
• Form choice: Capsule or oral drops for my pet?
• Administration tips: How to give safely and comfortably?
• Monitoring: What signs suggest improvement or problems?
• Course length: How long should therapy continue?
• Rechecks: Do you recommend follow-up or culture?
• Alternatives: What options exist if response is limited?

Authoritative Sources

For official product details, see the manufacturer’s page from Zoetis: Zoetis Antirobe Product Information. For additional regulatory context and listings, consult the FDA Animal Drugs search portal: FDA Animal Drug Database. Reference pharmacology for clinicians is also available in the Merck Veterinary Manual: Lincosamides Overview.

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Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.