Antirobe® (Clindamycin) for Dogs and Cats

What Antirobe® Is and How It Works

Antirobe® is a veterinary formulation of clindamycin used in dogs and cats for certain bacterial infections, including skin and soft tissue infections, dental infections, abscesses, and some bone infections. It is available as capsules (including antirobe 25mg capsules, antirobe 75 mg, antirobe 150 mg, and antirobe 300mg for dogs) and as Antirobe Aquadrops oral liquid. CanadianInsulin is a prescription referral service. Prescriptions are verified with your clinic, and orders are filled by licensed Canadian pharmacies.

Clindamycin is a lincosamide antibiotic. It inhibits bacterial protein synthesis by binding the 50S ribosomal subunit. This action helps reduce bacterial growth in susceptible strains, including many anaerobes commonly present in dental and deep tissue infections. Antirobe for dogs is widely used when culture and susceptibility support clindamycin. Antirobe for cats is also used in situations where a veterinarian deems clindamycin appropriate.

Form options help match dosing needs. Antirobe capsules for dogs come in several strengths, including antirobe clindamycin 75 mg and antirobe clindamycin 150mg. Antirobe Aquadrops for dogs and Antiobe Aquadrops for cats provide a liquid choice when small or precise doses are required. While ear infections often need topical therapy, antirobe for dogs ear infection may be considered in selected cases if bacteria are susceptible and a veterinarian recommends systemic treatment.

For a deeper overview of uses and safety, see Antirobe Capsules For Pet Health Uses Benefits And Safety.

Dosage and Usage

• The veterinarian determines the dose based on your pet’s weight, infection type, and culture results when available. Courses often run 7–28 days; bone infections may require longer.
• Capsules: Give whole. Follow with a small meal or water to reduce the chance of esophageal irritation, especially in cats.
• Aquadrops: Shake well. Measure the prescribed volume using a marked oral syringe for accuracy. Administer slowly to avoid aspiration.
• Give doses at evenly spaced times once or twice daily, as directed. Keep a simple schedule to support consistent levels.
• Continue for the full prescribed course, even if signs improve sooner. Stopping early can allow relapse or resistance.
• Missed dose: If a dose is missed, give it when remembered unless it is close to the next scheduled dose. Do not double up.
• Observe for vomiting, diarrhea, or reduced appetite during therapy. Note changes and contact the clinic if concerns arise.

• Store capsules and liquid at 20–25°C (68–77°F). Short trips between 15–30°C (59–86°F) are generally acceptable.
• Keep in the original, child‑resistant container. Protect from moisture and direct light.
• Do not freeze Antirobe Aquadrops. Shake before each dose.
• Check the package and bottle for expiry dates. Use opened liquid within the time on the label.
• When traveling, pack medicine in your carry‑on, with a copy of the prescription. Keep it upright and away from heat or car interiors.
• Use a weekly organizer only if the veterinarian approves and capsules are suitable; keep liquids in the original bottle.

Benefits and Savings

Antirobe clindamycin targets many anaerobic and gram‑positive bacteria implicated in dental infections, bite wounds, and deep soft tissue infections. Flexible strengths, such as antirobe 25 mg for dogs, antirobe 75 mg for dogs, and antirobe 150 mg for dogs, help veterinarians tailor doses. Antirobe Aquadrops for cats and small dogs make dosing easier when small volumes are needed.

Capsules are convenient for routine dosing, and the liquid can help with small or reluctant patients. Many caregivers see improvements in comfort and wound appearance as bacterial burden drops, while completing the full course supports long‑term control.

Many customers save 60–80% vs typical U.S. prices. We work with licensed, vetted partner pharmacies to source authentic brand medications with a broad selection and value‑focused pricing.

Side Effects and Safety

• Gastrointestinal upset (vomiting, diarrhea, soft stools)
• Reduced appetite or drooling
• Lethargy or decreased activity
• In cats, possible esophageal irritation if tablets or capsules are given without food or water
• Occasional increased thirst or mild dehydration from GI losses

Serious reactions are uncommon but can include allergic responses, severe or bloody diarrhea consistent with antibiotic‑associated colitis, or liver enzyme elevations. Do not use in pets allergic to clindamycin or lincomycin. Use caution in liver or kidney disease, during pregnancy or lactation, and in very young or debilitated animals. Do not use in rabbits, hamsters, guinea pigs, horses, or other hindgut fermenters. Clindamycin may interact with macrolides (e.g., erythromycin) and neuromuscular blockers; veterinarians assess combinations to avoid reduced antibiotic effect or adverse events.

Onset Time

Many pets show early improvement within 48–72 hours as pain, swelling, or drainage begin to lessen. Skin and soft tissue infections often respond within the first week. Dental infections may show improved comfort and appetite in a few days. Bone infections respond more slowly and may require several weeks of steady therapy and follow‑up. Complete the full course to support durable results even if signs improve early.

Compare With Alternatives

Veterinarians choose antibiotics based on likely pathogens, culture results, and tissue penetration. Compared with amoxicillin/clavulanate (Clavamox), which is often used for broad soft‑tissue coverage, Antirobe clindamycin offers strong anaerobic coverage and deep tissue penetration, which can be valuable for dental or bite‑wound infections when susceptible bacteria are present.

Cefpodoxime (Simplicef) offers once‑daily dosing and broad gram‑negative coverage, which some clinics prefer for certain skin infections. Cefovecin (Convenia) is a long‑acting injectable cephalosporin that can be useful when oral dosing is difficult. Antirobe may be preferred when anaerobes are suspected or confirmed, or when a lincosamide’s pharmacology is advantageous for bone or dental tissues.

Each option has different spectra, dosing schedules, and potential side effects. Culture and susceptibility testing help guide targeted therapy and prudent antibiotic stewardship.

Combination Therapy

• Dental care: Antirobe is often combined with dental cleaning, extractions, and oral rinses to address infection sources and reduce recurrence.
• Wound management: May be paired with wound debridement, flushing, and appropriate dressings for bite wounds or abscesses.
• Pain control: NSAIDs or other analgesics can be used for comfort when appropriate; veterinarians balance risks and benefits.
• Topicals: Skin or ear topicals may be added when culture supports mixed infections needing local therapy.
• Drug interactions: Clinicians may avoid macrolides given possible antagonism with lincosamides. Background therapies are adjusted as needed.

Patient Suitability and Cost‑Saving Tips

Antirobe antibiotics for dogs and cats are considered when infections involve susceptible bacteria and when the pet can take an oral capsule or liquid. It may not be appropriate for pets with a history of lincosamide allergy, certain gastrointestinal conditions, or for species sensitive to lincosamides (such as rabbits and guinea pigs). Caution is used in pregnancy, lactation, hepatic impairment, and in very young animals; veterinary guidance is essential.

Cost‑saving approaches can include selecting the strength that minimizes splitting or waste, choosing capsules when suitable, and planning multi‑month supplies for protracted courses like osteomyelitis, if prescribed. Ordering a little ahead helps avoid gaps. Prompt, express, cold‑chain shipping maintains product integrity from our partner pharmacies to your door.

Authoritative Sources

Zoetis Antirobe product information (capsules and oral liquid)

Health Canada Drug Product Database: search Antirobe

Merck Veterinary Manual: Lincosamides (clindamycin) overview

Order Antirobe® from CanadianInsulin: add to cart, upload your prescription, and we ship with prompt, express, cold‑chain handling.

This page is educational and does not replace your veterinarian’s advice. Always follow your clinic’s directions for dosing, monitoring, and follow‑up.