Please note: a valid prescription is required for all prescription medication.
Azithromycin 250 mg Tablets for Bacterial Infections
Sitewide Super Sale - Get 15% off when you buy 3 or more of the same product using the code LESS15 at checkout.
Applies to all products originating from Canada. Maximum quantity limited to a 90-day supply per order.
Black Friday Bonus - Spend $700 or more and get an extra $50 off at checkout with the code PLUS50.
Can be combined with the Sitewide Super Sale.
Enter each coupon code separately at checkout. Offer ends December 5, 2025.
Price range: $25.10 through $132.99
You save


Azithromycin is an oral antibiotic in the macrolide class. It treats susceptible bacterial infections in adults and children. This page outlines uses, dosing, safety, and access options with US delivery from Canada, including choices without insurance.
What Azithromycin Is and How It Works
CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
This medicine inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It may help in respiratory, skin, and certain genitourinary infections caused by susceptible organisms. The azithromycin 250 mg oral tablet is typically taken once daily. Effects can vary by pathogen and site of infection. Always follow the approved label and your prescriber’s instructions.
It is not active against viruses like the common cold or flu. Using antibiotics only when indicated helps reduce resistance.
Who It’s For
Approved indications include acute bacterial sinusitis, community-acquired pneumonia, pharyngitis and tonsillitis, uncomplicated skin infections, and urethritis or cervicitis due to susceptible organisms. It may be used for azithromycin 250 mg for strep throat when appropriate, such as in patients who cannot take first-line options. Selection depends on local resistance patterns and clinical judgment.
People with a history of hypersensitivity to macrolides or ketolides should avoid this therapy. Use caution in those with known QT prolongation, arrhythmias, low potassium or magnesium, significant hepatic disease, or myasthenia gravis. For broader options, see our Bacterial Infections category.
Dosage and Usage
Typical regimens are infection-specific. Adult schedules often include an initial higher dose on day 1 followed by lower daily doses for a short course. In some cases, a single-dose regimen is used for certain sexually transmitted infections. Pediatric use is weight-based. The azithromycin 5 day dose pack 250 mg oral tablet is a commonly prescribed schedule; the exact total dose and duration depend on indication and labeling.
Take with a full glass of water. It can be taken with or without food; a light meal may help stomach upset. Avoid taking aluminum- or magnesium-containing antacids at the same time; separate by several hours. Do not crush or split tablets unless the label and your prescriber say it is acceptable.
Strengths and Forms
Multiple presentations exist; availability can vary by supplier and region.
- azithromycin 250 mg tablets USP
- 500 mg tablets
- Oral suspension (commonly 200 mg per 5 mL; other strengths exist)
- Extended-release oral suspension (single-use bottle; adult indications)
Not all strengths, pack sizes, or manufacturers are always in stock.
Missed Dose and Timing
If a scheduled tablet is missed, take it when remembered unless it is close to the next dose. If it is nearly time for the next dose, skip the missed dose and resume the regular schedule. Do not double up. For best results, complete the full prescribed course even if symptoms improve earlier.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep medicines in the original container with the label intact and out of reach of children and pets. When traveling, pack your medicine in carry-on baggage, bring a copy of the prescription, and keep doses on a consistent schedule across time zones. Dispose of expired or unused tablets according to local guidance.
Benefits
- Once-daily dosing for most indications
- Short-course therapy for many infections
- Oral formulation suits home treatment
- Option for patients who cannot take beta-lactam antibiotics
- Broad clinical experience across common infections
Side Effects and Safety
- Diarrhea or loose stools
- Nausea or vomiting
- Abdominal pain
- Headache
- Changes in taste
Serious risks are uncommon but can include allergic reactions, severe skin reactions, liver injury, irregular heart rhythm including QT prolongation, and Clostridioides difficile–associated diarrhea. Seek urgent care for symptoms such as swelling of the face or throat, severe rash, yellowing of the skin or eyes, chest pain, fainting, or persistent severe diarrhea. Report side effects to a healthcare professional.
Drug Interactions and Cautions
- Separate from aluminum- or magnesium-containing antacids by several hours
- Monitor with warfarin; interactions may increase anticoagulant effects
- Potential interaction with digoxin and certain immunosuppressants
- Use caution with other QT-prolonging medicines
- Tell a prescriber about liver disease, kidney issues, or myasthenia gravis
Some chronic therapies may interact or overlap in side effect profiles. For background on other common drug classes, see Common Diabetes Medications. Always review a full medication list, including over-the-counter products and supplements, with a healthcare professional.
What to Expect Over Time
Symptoms may change as the infection responds, but the pattern varies by condition and site. Continue the full course as prescribed. Skipping doses can reduce effectiveness and promote resistance. Use reminders if needed. If symptoms worsen or do not improve as expected, contact a clinician. Do not share antibiotics or save them for future illness. Follow-up testing or imaging may be advised for certain diagnoses.
Compare With Alternatives
Other antibiotics may be recommended based on the organism, site of infection, and local resistance patterns. Tetracyclines such as Doxycycline are often used for respiratory and skin infections when appropriate. First-generation cephalosporins like Cephalexin are options for certain skin and soft tissue infections. Selection should follow clinical guidelines and susceptibility data.
Pricing and Access
We list transparent options to help compare formulations and pack sizes. Check azithromycin 250 mg Canadian pricing on the product page to see current availability and typical out-of-pocket ranges. Orders include secure payment and encrypted checkout. We provide Promotions when available. Products are offered with US shipping from Canada. Many patients use cash-pay routes; others submit receipts to insurance per their plan rules.
Availability and Substitutions
Stock levels can change. If a specific brand, pack, or strength such as azithromycin dihydrate 250 mg is unavailable, a prescriber may recommend a therapeutically appropriate alternative. Equivalent generics may vary in manufacturer and packaging. We cannot guarantee substitutions without a matching prescription.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults and children when a macrolide is indicated and tolerated. It may not suit patients with macrolide allergy, significant hepatic disease, or known risk factors for QT prolongation. Ask about multi-month quantities when appropriate, as larger fills can reduce per-tablet costs. Enable refill reminders so treatment courses are not interrupted. Keep medicines organized in a daily pillbox and bring a list of current medications to each appointment.
Questions to Ask Your Clinician
- Most appropriate diagnosis and expected course
- Preferred regimen and duration for this infection
- Whether a Z-Pak schedule is suitable
- Which symptoms require urgent evaluation
- How to space doses around antacids or supplements
- Whether lab tests or follow-up are needed
- If other therapies are ongoing, see Insulin Conversions or BD Needles Uses for general education
Authoritative Sources
Ready to proceed? Order at CanadianInsulin for express delivery with temperature-controlled handling when required. Ships from Canada to US. This information is not a substitute for professional medical advice; always consult a healthcare professional.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What infections does this antibiotic treat?
This macrolide is used for susceptible bacterial infections. Common indications include acute bacterial sinusitis, community-acquired pneumonia, pharyngitis or tonsillitis, uncomplicated skin infections, and certain urogenital infections. It is not effective against viruses. Choice depends on local resistance patterns and clinical factors such as allergy history and comorbidities. A clinician may also consider culture data when available. Always follow the approved label for the specific product dispensed.
How is the 5‑day pack generally taken?
The familiar 5‑day schedule often uses a higher starting dose on day 1, followed by once‑daily doses on days 2 through 5. The exact tablet strength and total amount are defined by the indication and the label. Take doses at roughly the same time each day. Avoid aluminum‑ or magnesium‑containing antacids near dosing. Do not change or extend the schedule without guidance from a prescriber.
Can it be taken with food or antacids?
It may be taken with or without food. A light snack can help reduce stomach upset. Avoid taking it at the same time as aluminum‑ or magnesium‑containing antacids because they can reduce absorption. Separating by a few hours is commonly advised on labels. Water is preferred for swallowing tablets. Ask a clinician about spacing other supplements such as iron or calcium if needed.
What are common and serious side effects?
Common effects include diarrhea, nausea, abdominal pain, vomiting, and headache. Serious risks are uncommon but can involve allergic reactions, severe skin reactions, liver injury, irregular heartbeat including QT prolongation, and C. difficile‑associated diarrhea. Seek urgent care for swelling of the face or throat, severe rash, yellowing of the skin or eyes, chest pain, fainting, or persistent severe diarrhea. Report adverse effects to a healthcare professional.
Who should avoid this therapy?
People with known hypersensitivity to macrolides or ketolides should avoid it. Caution is advised in those with significant hepatic disease, history of cholestatic jaundice with prior use, QT prolongation, arrhythmias, low potassium or magnesium, or myasthenia gravis. Always inform a prescriber about all medicines, supplements, and significant medical history before starting therapy.
What should be done after a missed dose?
If a dose is missed, take it when remembered unless it is near the time of the next one. If it is almost time for the next scheduled dose, skip the missed dose and continue with the regular plan. Do not double the dose. Completing the full course is important for effectiveness and to help reduce antibiotic resistance.
How do ordering and refills work here?
Place an order on the product page and upload a valid prescription if required. Our team confirms the prescription details with the prescriber when needed. Licensed Canadian pharmacies dispense the medicine. Refill timing depends on the prescription and availability. Keep medicines stored safely and consider enabling refill reminders on your account to prevent gaps in therapy.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
You Might Also Like
Related Articles
Zepbound Storage: How to Keep It Safe and Effective
Zepbound (tirzepatide) is a major advancement in chronic weight management. This once-weekly injection works best when stored and handled properly. Temperature, light exposure, and how long it stays out of…
Zepbound and Fatigue: Simple Ways to Feel Better
Starting a new weight loss medication like Zepbound can be exciting, especially if it promises lasting results. But for many patients, Zepbound and fatigue seem to go hand in hand,…
Mounjaro Heart Benefits That Go Beyond Weight Loss
Weight loss often steals the spotlight when people talk about Mounjaro, but the story doesn’t end there. Did you know that cardiovascular disease remains the leading cause of death for…
Ozempic Rebound: How to Prevent Weight Regain
Weight loss with medications like Ozempic has become a life-changing experience for many. People who struggled for years to lose weight are finally seeing results: lower numbers on the scale,…

