Bupropion XL

Uses of Bupropion XL

Bupropion XL is a flexible medication primarily employed in treating seasonal affective disorder (SAD) and depression. It also helps people quit smoking and manage their weight. With the active ingredient Bupropion, it’s available under various brand names like Wellbutrin, Zyban, Auvelity (with dextromethorphan), and Contrave (with naltrexone). Bupropion XL is trusted for its ability to regulate mood, reduce nicotine cravings, and, when used with naltrexone, control appetite.

Precautions and Warnings

Before starting Bupropion XL, it’s important to consider some precautions. If you have a history of seizures, eating disorders, or have recently stopped alcohol, seizure medications, or sedatives, it’s best to avoid this medication. Also, don’t take Bupropion XL with other medications containing Bupropion, like Wellbutrin or Contrave. Wait at least 14 days before or after using MAO inhibitors. Especially if you’re under 24 years old, watch for any signs of suicidal thoughts or changes in behavior when starting Bupropion XL.

Dosage

Dosage recommendations for Bupropion XL vary depending on the condition being treated. For depression, the usual starting dose is 150 mg once daily, preferably in the morning, with potential escalation to 300 mg once daily after a week. 

The maximum daily dose should not surpass 300 mg. To quit smoking, the usual starting dose is 150 mg once daily for three days, then increased to 150 mg twice daily. Adjustments to the dosage may be required depending on individual response and tolerance.

Side Effects

Common side effects:

• Dry mouth
• Sore throat
• Blurred vision
• Nausea
• Vomiting
• Headache

Severe side effects:

• Seizures
• Changes in mood
• Irregular heartbeat
• Manic episodes