Please note: a valid prescription is required for all prescription medication.
Invokana® is an oral SGLT2 inhibitor for adults with type 2 diabetes. This page explains how it works, who it’s for, and how to use it safely. You also get practical details on access, including US delivery from Canada and the Invokana price without insurance.
CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
What Invokana Is and How It Works
This medicine belongs to the SGLT2 inhibitor class. It lowers blood sugar by reducing glucose reabsorption in the kidneys, which increases urinary glucose excretion. Clinical guidance also notes potential benefits for certain heart and kidney outcomes in adults with type 2 diabetes, consistent with approved labeling. Effects may include modest reductions in body weight and blood pressure.
Because it targets renal glucose handling, hydration status matters. Volume depletion can occur, especially in older adults or those on diuretics. Talk with your healthcare professional about monitoring, including kidney function and electrolytes. For background on this class, see SGLT2 Heart Failure Care and Common Diabetes Medications. Patients new to tablets may also explore Oral Diabetes Medications.
For those comparing budgets across therapies, the Canagliflozin price can vary by strength, supply length, and manufacturer.
Who It’s For
The treatment is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It may be considered when metformin alone is insufficient or when a prescriber chooses an SGLT2 inhibitor for additional kidney or cardiovascular considerations per labeling. It is not indicated for type 1 diabetes or for diabetic ketoacidosis.
People with severe renal impairment, volume depletion, active foot ulcers, or a history of serious genital infections may require special caution. Those with peripheral vascular disease or neuropathy should maintain careful foot care and discuss risks. Patients on insulin or sulfonylureas may face increased hypoglycemia risk. For patients planning long-term therapy, the Canagliflozin 100 mg price is one factor among clinical priorities and monitoring needs.
Dosage and Usage
The usual starting dose is 100 mg once daily, taken before the first meal of the day. Based on response and kidney function, some patients may be maintained at 100 mg or considered for 300 mg once daily. Swallow tablets whole with water. Maintain adequate fluid intake unless otherwise directed by your prescriber.
Dosing choices depend on individual renal function, concomitant medications, and tolerability. When uncertain, defer to the official prescribing information and your clinician’s guidance. If hypoglycemia occurs with background insulin or sulfonylureas, your prescriber may adjust those agents. For everyday management context, review our category page on Type 2 Diabetes.
Some patients may ask about higher strength affordability while planning therapy; discussions often include total monthly fills, not just sticker figures, instead of focusing solely on list numbers.
Strengths and Forms
This medicine is available as film‑coated tablets in 100 mg and 300 mg strengths. Availability can vary by market and supplier. The Canagliflozin tablets 100 mg price can differ from the higher strength due to manufacturer and supply factors.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume your usual schedule. Do not take two doses at once. Try to take the tablet before the first meal each day to align with label guidance. Keep a simple reminder system to maintain a consistent routine.
Storage and Travel Basics
Store tablets at room temperature, away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not store in a bathroom where humidity is high. When traveling, carry the original labeled container in your hand luggage. Bring a copy of your prescription and a medication list. Pack enough supply for your trip, plus a small buffer in case of delays. Follow disposal instructions from your pharmacist or local guidance when you no longer need the product.
Benefits
This therapy lowers blood glucose by increasing urinary glucose excretion. It can reduce A1C when used as directed and may aid modest weight and blood pressure changes. In specific patients with type 2 diabetes and certain kidney or cardiovascular risks, it may contribute to improved outcomes per approved indications. Oral once-daily dosing supports simplicity for many adults who prefer a tablet regimen.
Side Effects and Safety
- Genital yeast infections
- Urinary tract infections
- Increased urination
- Thirst or dry mouth
- Nausea or constipation
- Dizziness from volume depletion
Serious but less common risks include ketoacidosis, Fournier’s gangrene, severe urinary infections, acute kidney injury, fractures, and, in some patients, increased risk of lower-limb complications. Hypoglycemia can occur when combined with insulin or sulfonylureas. Seek medical attention for symptoms of severe infection, significant abdominal pain, severe dehydration, or signs of ketoacidosis such as nausea, vomiting, abdominal pain, and rapid breathing. Read the Medication Guide and speak with your healthcare professional for full safety details.
Drug Interactions and Cautions
Diuretics may increase the risk of volume depletion. ACE inhibitors, ARBs, or potassium‑sparing agents may affect potassium in some patients. Digoxin concentrations can be increased; monitoring may be considered. Enzyme inducers such as rifampin may lower exposure. Alcohol misuse can raise ketoacidosis risk. Always provide a complete medication and supplement list to your prescriber and pharmacist.
What to Expect Over Time
Many patients notice more frequent urination early in treatment. Genital symptoms, when they occur, often respond to standard care. Blood glucose improvements typically require consistent daily use along with diet and activity. Your prescriber may check kidney function and electrolytes periodically. Foot care, hydration, and attention to infection symptoms can support safe, steady use. If your plan changes, never stop or switch medicines without discussing it with your clinician.
Compare With Alternatives
SGLT2 inhibitors differ in study data, dosing ranges, and labeled indications. Two common alternatives include Jardiance and Farxiga Dapagliflozin. Metformin is frequently used as the foundation in type 2 diabetes and may be combined with an SGLT2 inhibitor when appropriate. Your prescriber will select a regimen based on goals, kidney function, comorbidities, and tolerability.
Pricing and Access
Canadian pharmacy pricing can offer value compared with some retail figures. For those comparing total spend, formulary status and supply length matter as much as list numbers. If you are evaluating generics by maker, the Canagliflozin generic price can differ between manufacturers and pack sizes. We arrange fulfilment through licensed pharmacies, with orders that Ships from Canada to US after prescription verification. For broader education on budgeting and therapy choices, browse our category on Blood Sugar Control.
Check current availability on the product page before you place an order. See our site’s offers page for occasional coupons and updates at Promotions. We use encrypted checkout to protect your information.
Availability and Substitutions
Supply can vary by strength and manufacturer. If a specific presentation is unavailable, your prescriber may recommend a therapeutically appropriate alternative in the same class or an adjusted plan consistent with your medical history. Patients comparing high-strength options often review budget alongside clinical needs; for example, the Canagliflozin 300 mg price may differ from lower strengths depending on supplier.
Patient Suitability and Cost-Saving Tips
Good candidates typically include adults with type 2 diabetes who need additional glucose lowering and for whom an SGLT2 inhibitor is appropriate. Those with severe renal impairment, frequent infections, or recurrent dehydration may require a different plan. Pregnant or breastfeeding patients should consult their prescriber about safer options.
Cost-saving ideas include 90‑day refills when appropriate, aligning refill dates with other medicines, and setting reminders to avoid gaps in therapy. Ask your clinician if a lower strength titration phase is planned, since partial bottles can complicate budgeting. If you are paying cash, comparing quotes from multiple suppliers can help, and the Canagliflozin price without insurance can vary by pack size and maker.
Questions to Ask Your Clinician
- Is an SGLT2 inhibitor suitable given my kidney function?
- Should I adjust my insulin or sulfonylurea to reduce hypoglycemia risk?
- What signs of infection or ketoacidosis should prompt urgent care?
- How often should labs be checked, including renal function and electrolytes?
- Would a different class offer similar benefits for my goals?
- Can I coordinate a 90‑day fill to simplify refills and planning?
Authoritative Sources
Janssen Prescribing Information
Health Canada Drug Product Database
Ready to proceed? Add the tablets to your cart to review options, then complete checkout with express shipping and US shipping from Canada. Prescription required; temperature-controlled handling when required. This content is educational and not a substitute for professional medical advice.
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How does this SGLT2 inhibitor lower blood sugar?
It works in the kidneys by blocking the SGLT2 transporter. This reduces glucose reabsorption and increases urinary glucose excretion. The result can be lower fasting and post‑meal blood sugars when used with diet and activity. Some people notice more frequent urination early on. Your prescriber may monitor kidney function and electrolytes, especially if you use diuretics or have dehydration risks.
Who should not use this medicine?
It is not for type 1 diabetes or for treating diabetic ketoacidosis. People with severe renal impairment, frequent severe infections, or a history of serious genital infections may need a different plan. Those with active foot ulcers or significant peripheral vascular disease should discuss risks and foot care. Pregnant or breastfeeding patients should talk with their clinician about alternatives supported by guidelines.
When should I take my daily dose?
The tablet is usually taken once daily before the first meal. Try to take it around the same time each day. If you miss a dose and remember later the same day, take it then. If it is close to the next dose, skip the missed dose. Do not double doses. Follow the official label and your prescriber’s instructions for individualized guidance.
What side effects should I watch for?
Common effects include genital yeast infections, urinary tract infections, increased urination, thirst, and dizziness from volume depletion. Serious but less frequent problems can include ketoacidosis, severe urinary infections, Fournier’s gangrene, acute kidney injury, fractures, and limb complications in some patients. Seek urgent care for severe abdominal pain, fever, signs of infection, or symptoms of ketoacidosis such as nausea and rapid breathing.
Can it cause low blood sugar by itself?
On its own, this class has a low risk of hypoglycemia. The risk can increase when used with insulin or sulfonylureas. Your prescriber may adjust background therapies to reduce lows. Monitor glucose regularly, carry a source of fast carbohydrates if advised, and report any recurring episodes to your clinician for evaluation.
How is kidney function considered with therapy?
Kidney function guides dosing choices and whether therapy is appropriate. Your clinician may check estimated glomerular filtration rate and electrolytes before and during treatment. In some patients, only certain strengths are recommended. If kidney function changes, your prescriber may reassess the plan according to official labeling and your overall management goals.
What else can support success with this treatment?
Consistency helps. Take the tablet daily as directed, follow your meal plan, and stay hydrated. Keep foot care routines and watch for infection symptoms. Set refill reminders, and consider a multi‑month supply if appropriate. Regular follow‑ups allow your prescriber to monitor labs, review side effects, and adjust your regimen if needed to maintain a safe, effective plan.
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