Cardalis® Tablets for Canine Heart Failure

What Cardalis Is and How It Works

Cardalis® is a veterinary prescription tablet that combines benazepril, an ACE inhibitor, with spironolactone, an aldosterone blocker. It is used to manage congestive heart failure caused by degenerative valve disease in dogs. You can order with US delivery from Canada, even Cardalis without insurance. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order. This page outlines how the medicine works, how to give it, and key safety points.

Benazepril reduces the production of angiotensin II, which relaxes blood vessels and can lessen the heart’s workload. Spironolactone blocks aldosterone’s effects, which may help limit fluid retention and cardiac remodeling. Together, the combination targets the renin-angiotensin-aldosterone system from two angles. Your veterinarian may use the treatment alongside diuretics or other cardiac therapies for comprehensive care. For condition basics and symptom overviews, see our resource on Canine Heart Failure.

Who It’s For

This therapy is indicated for dogs with symptomatic congestive heart failure linked to atrioventricular valve degeneration. In many cases, veterinarians consider Cardalis for dogs when cough, exercise intolerance, or fluid buildup appears despite lifestyle measures. It may be part of a multimodal plan that includes diet adjustments and other cardiac medicines.

Do not use the tablets in cats. Avoid use in dogs that are pregnant, lactating, or intended for breeding unless your veterinarian decides benefits outweigh risks. Dogs with hyperkalemia, Addison’s disease, severe kidney dysfunction, or known hypersensitivity to ACE inhibitors or spironolactone may not be suitable. Your veterinarian will evaluate kidney values, electrolytes, and blood pressure before starting and during therapy.

Dosage and Usage

Follow your veterinarian’s prescription exactly. Typical regimens use once-daily dosing with food. Giving the dose with a meal can support spironolactone absorption and may reduce stomach upset. Tablets are scored; your veterinarian may instruct you to split a tablet to match your dog’s weight-based dose.

The labeled dose is based on body weight and provides both benazepril and spironolactone in fixed proportions. If any vomiting, diarrhea, or appetite changes occur after dosing, contact your clinic for guidance. As with any Cardalis medication, do not adjust the dose or stop therapy without veterinary advice. Fresh drinking water should be available, and periodic blood tests are commonly recommended.

Strengths and Forms

The product is supplied as scored oral tablets in several fixed-dose combinations. Availability can vary by pharmacy and stock.

• 2.5 mg benazepril with 20 mg spironolactone
• 5 mg benazepril with 40 mg spironolactone
• 10 mg benazepril with 80 mg spironolactone

These Cardalis tablets are designed for once-daily administration with food. Your veterinarian will select the strength appropriate for your dog’s weight and clinical status.

Missed Dose and Timing

If you miss a dose, give it when you remember the same day with a small meal. If it is close to the next scheduled dose, skip the missed one and resume the regular schedule. Do not double up doses. Keeping a daily reminder or dosing journal can reduce missed or late doses.

Storage and Travel Basics

Store tablets in the original container with the label intact. Keep the bottle closed, protected from moisture, and out of reach of children and animals. Avoid excessive heat or freezing environments, and do not store in the bathroom where humidity is high. Check the expiration date before each refill cycle.

When traveling, keep Cardalis dog tablets in your carry-on along with a copy of the prescription. Use a pill organizer only if it is clearly labeled to prevent mix-ups. For longer trips, bring extra doses and your clinic’s contact information. Follow any regional rules on veterinary prescription transport, and keep medicines away from direct sunlight in the car.

Benefits

This combination therapy targets two hormonal pathways that influence fluid retention and cardiac strain. Using a single tablet may simplify routines compared with giving two separate medicines. Once-daily dosing with food can also help with adherence in many households.

By addressing neurohormonal activation, the treatment may help reduce congestion, improve comfort, and support quality of life under a veterinarian’s care. Regular monitoring allows your clinic to track response and adjust the overall plan when needed.

Side Effects and Safety

• Digestive upset: vomiting, diarrhea, or reduced appetite
• Lethargy: lower energy, especially at initiation
• Kidney-related changes: increases in creatinine or BUN on labs
• Electrolyte shifts: high potassium may occur
• Occasional cough or mild dehydration signs

Serious but less common risks include marked hyperkalemia, worsening kidney function, low blood pressure, or allergic reactions. If you notice collapse, severe weakness, facial swelling, or trouble breathing, seek urgent veterinary care. Wear gloves if advised when handling broken tablets, and wash hands after administration. Keep the medicine away from children. Humans should not ingest veterinary heart medications.

Drug Interactions and Cautions

Use caution with other agents that raise potassium, including potassium supplements or other potassium-sparing diuretics. Nonsteroidal anti-inflammatory drugs may affect kidney blood flow; your veterinarian will balance pain control with cardiac safety. Monitor closely if combining with diuretics such as Lasix or Furosemide Injection, as fluid status and electrolytes can shift. Avoid salt substitutes containing potassium unless your veterinarian approves.

Clinics sometimes use Cardalis and Vetmedin together, under supervision, to address different aspects of heart function. Never add or remove medicines without consulting your veterinarian. Provide a full list of prescriptions, supplements, and recent lab results at each visit so your care team can check for interactions.

What to Expect Over Time

With consistent dosing and follow-up, many dogs show easier breathing, better sleep, and improved activity tolerance. Appetite may stabilize as congestion improves. The pace and extent of changes vary by diagnosis, age, and other conditions. Your veterinarian will assess progress using history, physical exams, and periodic blood work.

Consistency matters. Give doses at the same time each day with food. Use a calendar, phone reminder, or dispenser to help keep dosing on track. If your veterinarian adjusts other therapies, such as diuretics or inodilators, they may also refine lab monitoring to keep your dog safe.

Compare With Alternatives

Veterinarians often combine a RAAS-targeting medicine with other heart failure therapies. Pimobendan, an inodilator, supports contractility and reduces afterload. You can compare options like Vetmedin and loop diuretics such as Salix to understand how each fits into a comprehensive plan. Your clinician will determine the right combination for your dog’s condition.

Pricing and Access

Canadian pharmacy sourcing can offer favorable pricing for many pet owners in the United States. If you are researching Cardalis price, check the product page to see current options and tablet strengths. Our checkout supports card payments, and encrypted checkout protects your information. If you are seeking a coupon, see current offers on our Promotions page.

Many customers prefer the convenience of our platform for US delivery with Canadian pricing. View the product details to compare strengths, then add the prescribed item to your cart. You can review cost differences between strengths before placing your order.

Availability and Substitutions

Supply can vary. If a specific strength is unavailable, your veterinarian may prescribe a different tablet strength or separate the components as individual prescriptions. For example, a clinician might use an ACE inhibitor and spironolactone as separate items if a fixed-dose tablet is not suitable. Your clinic will choose an option that matches your dog’s weight and lab profile.

In case of backorders, your veterinarian may recommend an alternative plan temporarily. Do not split or mix products unless your prescriber has provided explicit instructions.

Patient Suitability and Cost-Saving Tips

Not every dog is a candidate for ACE inhibition and aldosterone blockade. Dogs with significant kidney disease, high potassium, or low blood pressure need individualized plans. Your veterinarian will monitor labs after starting and during dose changes. Report reduced appetite, vomiting, weakness, or collapse promptly.

To manage expenses, consider a multi-month supply if your dog is stable and your veterinarian agrees. Align refills with routine checkups to reduce trips and ensure timely lab monitoring. If you are exploring broader purchasing guidance for pet therapies, see our article on Buy Pet Medications. You can also browse the full catalog of Pet Medications to compare therapies and packaging sizes.

Questions to Ask Your Clinician

• Diagnosis specifics: stage, imaging, and lab findings
• Therapy goals: symptom relief and monitoring plans
• Dose plan: timing with meals and splitting instructions
• Safety checks: kidney labs, electrolytes, and blood pressure
• Home care: exercise limits and sodium guidance
• Combination therapy: role of diuretics or inodilators
• Refills: how often to follow up for assessments

Authoritative Sources

For official prescribing information and approval details, consult these sources:

• Ceva Animal Health product information for veterinarians
• FDA Animal Drugs database listing for veterinary heart medicines
• Health Canada Drug Product Database for veterinary listings

Ready to proceed? You can place your order with prompt, express shipping and temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.