Contrave

Contrave is a prescription medication used for weight management. It is a combination of two active ingredients: bupropion and naltrexone. Bupropion is an antidepressant that also helps with appetite control, while naltrexone is typically used to treat addiction but works in this combination to enhance weight loss by influencing the brain’s reward system. Contrave is designed for adults with obesity or those who are overweight and have at least one weight-related health condition, such as type 2 diabetes or hypertension. It is typically used alongside a reduced-calorie diet and regular physical activity.

Benefits:

• Helps with appetite control and cravings by acting on the brain’s reward system.
• Promotes weight loss in individuals with obesity or those overweight with related health issues.
• Can improve blood sugar control, making it beneficial for people with type 2 diabetes.
• The combination of bupropion and naltrexone targets multiple pathways to support weight loss.
• When used with diet and exercise, Contrave has shown significant weight loss benefits in clinical trials.

Dosage:

• Start with 8 mg/90 mg (naltrexone/bupropion) once a day for the first week.
• Increase gradually to reach 32 mg/360 mg (naltrexone/bupropion) once a day by the end of the fourth week.
• The recommended maintenance dose is 32 mg/360 mg once a day, taken as one tablet in the morning.
• Contrave should be taken in conjunction with a reduced-calorie diet and regular physical activity for optimal weight loss.

Warnings and Precautions:

• Contrave is not recommended for individuals with uncontrolled high blood pressure, seizures, eating disorders (such as bulimia or anorexia), or alcohol/substance abuse.
• It can increase the risk of suicidal thoughts and behaviors, especially in younger individuals. Close monitoring is required during treatment.
• May cause an increase in blood pressure and heart rate. Regular monitoring is advised.
• Not recommended for use in pregnant or breastfeeding women.
• Always inform your healthcare provider about any other medications or supplements you are taking to avoid potential interactions.

Usage Instructions:

• Take Contrave exactly as prescribed by your healthcare provider.
• Swallow the tablets whole. Do not chew, crush, or split them.
• It is typically taken once in the morning, but your healthcare provider may adjust the timing based on your specific treatment plan.
• Do not take more than one tablet per day unless advised by your healthcare provider.

Storage Information:

• Store Contrave at room temperature, between 68°F to 77°F (20°C to 25°C).
• Keep the medication in its original container to protect from moisture.
• Do not store in a damp or wet area, such as a bathroom, and keep away from excessive heat.

Common Side Effects:

• Nausea, constipation, or headache.
• Dizziness, dry mouth, or trouble sleeping.
• Increased blood pressure or heart rate.
• Rarely, mood changes or thoughts of suicide; contact a healthcare provider immediately if these occur.
• Injection site reactions (if using injectable formulations) or other injection-related side effects.