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Dapagliflozin Tablets for Type 2 Diabetes
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Dapagliflozin is an oral SGLT2 inhibitor used for type 2 diabetes and certain heart or kidney conditions. This guide explains how it works, who it may suit, and how to use it, with US shipping from Canada. You can also compare Dapagliflozin price without insurance.
What Dapagliflozin Is and How It Works
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This medicine blocks sodium-glucose co-transporter 2 (SGLT2) in the kidney, which helps remove excess glucose through urine. The result can be lower blood sugar, reduced intravascular volume, and beneficial effects on heart and kidney outcomes. In the US, Dapagliflozin is marketed as Farxiga®. In some materials you may see the phrase Dapagliflozin trade name Forxiga.
By increasing urinary glucose and sodium excretion, the treatment may improve glycemic control and reduce the risk of hospitalization for heart failure. It can also slow the rate of kidney function decline in eligible patients. For background on the class, see SGLT2 Inhibitors.
Who It’s For
This therapy is indicated to improve glycemic control in adults with type 2 diabetes as an adjunct to diet and exercise. It is also indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure. Additionally, it is approved to reduce the risk of sustained decline in kidney function, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease.
It is not indicated for type 1 diabetes and may increase the risk of ketoacidosis in that population. Avoid use in patients with known hypersensitivity to the drug. Use caution in individuals with volume depletion, reduced kidney function, active urinary tract or genital infections, or those on loop diuretics. For condition-specific information, explore Type 2 Diabetes and Heart Failure.
Dosage and Usage
Tablets are taken once daily, with or without food, preferably at the same time each day. For glycemic control in type 2 diabetes, many adults start at a lower daily amount and may increase if additional effect is needed. For heart failure or chronic kidney disease indications, the typical daily amount is higher, per the approved label. If you are unsure about the correct schedule, follow your prescriber’s instructions and the official labeling.
Consider hydration, especially during illness, heat exposure, or when starting diuretics. The medicine may be temporarily interrupted for major surgery, prolonged fasting, or acute illness to reduce ketoacidosis risk. Resume when oral intake and clinical status are stable, as directed by your healthcare professional.
Strengths and Forms
Dapagliflozin is supplied as film-coated tablets in two commonly available strengths: 5 mg and 10 mg. Packaging and availability can vary by pharmacy and manufacturer.
Missed Dose and Timing
If you miss a dose, take it when you remember the same day. If it is close to your next scheduled time, skip the missed dose and take the next dose at the regular time. Do not take two doses at once. Try to take the tablet consistently to build a routine.
Storage and Travel Basics
Store tablets at room temperature in a dry place, in the original container, and out of reach of children and pets. Keep the container closed tightly to protect from moisture. When traveling, carry medicines in your hand luggage, bring a copy of your prescription, and keep the original labels visible. Do not leave tablets in a hot car or in direct sunlight. If you cross time zones, keep dosing intervals as steady as possible and ask your clinician for guidance when needed.
Benefits
This treatment can:
- Lower blood glucose as part of a comprehensive plan
- Reduce the risk of hospitalization for heart failure in eligible adults
- Slow kidney function decline in approved chronic kidney disease populations
- Offer once-daily oral dosing convenience
- Work independently of insulin secretion
These outcomes reflect labeled indications and supportive clinical data. For broader context on drug classes used in diabetes care, see Diabetes Medications or browse Blood Sugar Control options.
Side Effects and Safety
- Genital yeast infections
- Urinary tract infections
- Increased urination
- Thirst or dry mouth
- Nasal congestion or sore throat
- Dizziness, especially on standing
Serious risks can include ketoacidosis (including euglycemic ketoacidosis), severe urinary infections (urosepsis, pyelonephritis), acute kidney injury, volume depletion with low blood pressure, necrotizing fasciitis of the perineum (Fournier’s gangrene), and severe allergic reactions. Hypoglycemia can occur when used with insulin or sulfonylureas. Seek urgent care with symptoms of ketoacidosis such as nausea, vomiting, abdominal pain, fatigue, or labored breathing.
Drug Interactions and Cautions
Concurrent loop diuretics or situations that reduce fluid volume can raise the risk of hypotension and acute kidney injury. When combined with insulin or insulin secretagogues, the risk of low blood sugar increases. Enzyme inducers that affect UGT pathways may reduce exposure, although clinical impact is usually limited; follow the official label and your prescriber’s advice. Interrupt therapy for major surgery, prolonged fasting, or critical illness when ketoacidosis risk is elevated.
What to Expect Over Time
Some people notice increased urination shortly after starting. Glucose and sodium losses can lead to small changes in weight and blood pressure. Glycemic effects may build with steady daily use. Cardiovascular or renal risk-reduction benefits are evaluated over longer periods in clinical studies; your clinician will monitor progress with labs and routine checks. Consistent dosing, hydration, and recognizing early signs of infections or ketoacidosis can support safe, long-term use.
Compare With Alternatives
Other SGLT2 inhibitors may be appropriate based on your history and lab profile. Two common options are Jardiance® and Invokana®. Molecules in this class share a core mechanism but differ in labeling, renal thresholds, and interaction details. Your prescriber will determine which therapy aligns with your clinical goals and medical conditions.
Pricing and Access
We list Dapagliflozin tablets Canadian pricing for transparent comparison. You can also review Dapagliflozin cash price on the product page alongside pack sizes. To explore savings, compare generic and brand options and discuss longer refills with your prescriber. For ordering questions, check eligibility and submit your prescription; checkout is via encrypted processes. We provide US shipping from Canada on approved orders. For condition learning, you can also navigate our Type 2 Diabetes pages for context.
Savings CTA: See how Canadian pricing may lower out-of-pocket costs compared with typical retail rates, depending on your plan and eligibility. Pricing CTA: View current product options and add to cart to see total before confirming.
Availability and Substitutions
Supply can vary. If a specific pack or strength is unavailable, a prescriber may recommend a clinically suitable alternative from the same class. Dapagliflozin remains one option among several SGLT2 inhibitors for qualifying adults.
Patient Suitability and Cost-Saving Tips
Adults with type 2 diabetes who need additional glycemic control, those with heart failure, or those with eligible chronic kidney disease may be considered for this therapy. It is not for type 1 diabetes and should not be used in patients with known hypersensitivity to the drug. If you have recurrent genital or urinary infections, low blood pressure, or are on intensive diuretic regimens, discuss risks and monitoring plans.
- Multi-month fills: Ask your prescriber if longer supplies are appropriate
- Lab monitoring: Keep scheduled kidney function and glucose checks
- Sick-day plan: Know when to pause during acute illness
- Refill reminders: Set alerts so you can reorder on time
- Travel prep: Pack enough tablets plus documentation
Questions to Ask Your Clinician
- Which indication applies to me, and what outcome should we monitor?
- How does my kidney function affect choice and dosing?
- What are warning signs of ketoacidosis, and when should I seek care?
- How should I handle dosing around surgery, illness, or fasting?
- If I take insulin or a sulfonylurea, how do we reduce hypoglycemia risk?
- What labs will we check, and how often?
- Would another SGLT2 inhibitor better fit my clinical profile?
Authoritative Sources
AstraZeneca Farxiga Prescribing Information
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Can dapagliflozin help in chronic kidney disease without diabetes?
Yes. The drug is approved to reduce the risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease, even if diabetes is not present. Eligibility depends on kidney function and other clinical factors. Your healthcare professional will assess albuminuria, baseline eGFR, and co-medications to decide if this therapy is appropriate. Follow renal monitoring schedules outlined on the label, and avoid use if you are on dialysis or have a contraindication.
What are warning signs of ketoacidosis with this medicine?
Ketoacidosis can occur even with normal or near-normal glucose. Watch for nausea, vomiting, stomach pain, tiredness, and fast or deep breathing. Other signs may include confusion or unusual thirst. Risk increases with acute illness, low-carb or ketogenic dieting, prolonged fasting, surgery, or sudden insulin reduction. If these symptoms appear, stop taking the medicine and seek urgent medical care. Restart only when advised by your prescriber after clinical stability and a review of the underlying cause.
Does this treatment cause low blood sugar on its own?
This medicine has a low intrinsic risk of hypoglycemia when used alone because its action is independent of insulin. However, low blood sugar can occur when it is combined with insulin or a sulfonylurea. Your prescriber may adjust those agents to reduce risk. Learn how to recognize and manage symptoms of hypoglycemia, including shakiness, sweating, hunger, headache, and confusion. Keep glucose sources available and follow your clinician’s instructions for sick-day management.
How should I manage dehydration risks while taking diuretics?
The drug can increase urine output, and combining it with loop or thiazide diuretics may raise the chance of low blood pressure or acute kidney injury. Your clinician may review diuretic timing, ensure adequate fluid intake, and monitor kidney function. Be cautious during heat exposure, vomiting, diarrhea, or when starting or increasing diuretics. If you feel dizzy or lightheaded, sit or lie down and contact your healthcare professional to discuss next steps and monitoring.
Should I stop taking it before surgery or fasting?
For major surgery or prolonged fasting, your healthcare professional may advise temporarily stopping treatment to reduce ketoacidosis risk. The medicine is typically restarted when oral intake normalizes and you are clinically stable. Follow the timing on the approved label and the advice of your prescriber. If you plan a procedure, inform your care team in advance, and bring an up-to-date medication list to preoperative visits. Do not change your regimen without clinical guidance.
How can I reduce my out-of-pocket spending?
Discuss longer refills, use of generics, and whether your plan covers this class. Some patients compare Forxiga price without insurance to see potential savings relative to local retail. Ask your prescriber about therapeutic alternatives in the same class if access is limited. Review pharmacy pricing on the product page, and consider aligning refills with lab visits to avoid gaps in therapy. Always ensure the product and strength match your prescription.
How is this different from metformin?
Metformin reduces liver glucose production and improves insulin sensitivity, while SGLT2 inhibitors increase urinary glucose excretion. The agents can be used together when appropriate. Selection depends on A1C targets, kidney function, heart failure or kidney disease status, tolerance, and co-medications. Your clinician will individualize therapy based on guidelines and your medical history. Neither medicine replaces lifestyle measures such as nutrition, activity, and weight management within an overall diabetes care plan.
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