Deramaxx® Tablets for Dogs

Deramaxx® is a prescription nonsteroidal anti-inflammatory medicine for dogs that helps control osteoarthritis pain and post-operative discomfort. With US delivery from Canada and Canadian pricing, it offers a convenient way to access a trusted veterinary NSAID across borders. Flavored tablets make dosing straightforward for many dogs.

What Deramaxx® Is and How It Works

Deramaxx® (deracoxib) is a COX-2 selective NSAID that reduces prostaglandin production to help ease inflammation, swelling, and pain. It is commonly prescribed for chronic osteoarthritis and for short-term control of pain after orthopedic or dental surgery. At CanadianInsulin, orders are prescription-checked with your clinic and dispensed by a licensed Canadian pharmacy. This cross-border service ships from Canada to the US and supports cash-pay families; even those without insurance often find it more affordable.

By preferentially inhibiting COX-2, Deramaxx is designed to provide analgesia while aiming to preserve protective COX-1 activity in the gastrointestinal tract and kidneys. As with all NSAIDs, appropriate dosing and monitoring remain important, especially during longer courses or when other conditions are present. Many clinicians incorporate Deramaxx within a broader pain plan that may include controlled exercise, weight management, and joint-supportive strategies.

For a primer on safety and use, see Deramaxx For Dogs.

Who Deramaxx Is For

Indications include control of pain and inflammation associated with osteoarthritis in dogs, and control of postoperative pain following orthopedic or dental procedures. It is not for use in cats.

• Appropriate for adult dogs with diagnosed osteoarthritis requiring ongoing pain control.
• Used short term for pain following orthopedic or dental procedures when prescribed by a veterinarian.
• Avoid in dogs with known hypersensitivity to deracoxib or other NSAIDs.
• Use caution in dogs with gastrointestinal ulceration, bleeding disorders, dehydration, kidney, liver, or heart disease.
• Safety has not been established in pregnant, breeding, or lactating dogs, or in very young puppies.
• Dogs receiving medications that affect the kidneys, liver, or clotting may need closer monitoring.

Learn more about joint disease patterns in Arthritis In Dogs.

Dosage and Usage

Follow the prescribing veterinarian’s directions and the approved label. Typical labeled ranges include:

• Osteoarthritis: 1–2 mg/kg (0.45–0.91 mg/lb) by mouth once daily.
• Postoperative pain: 3–4 mg/kg (1.4–1.8 mg/lb) by mouth once daily for up to seven days.

Chewable tablets may be offered by hand or with a small amount of food; administration with food can reduce stomach upset. Provide fresh water at all times. Do not use with other NSAIDs, corticosteroids, or aspirin unless specifically directed by the veterinarian. Use the lowest effective dose for the shortest duration compatible with treatment goals, and consider periodic bloodwork for longer-term therapy. If appetite or behavior changes develop, contact the clinic before continuing therapy.

For related therapies and supportive care, browse Pet Medications.

Strengths and Forms

Deramaxx is supplied as flavored chewable tablets in multiple strengths commonly used by veterinarians, including 12 mg, 25 mg, 75 mg, and 100 mg. Package sizes and availability may vary based on stock and prescription needs.

Missed Dose and Timing

If a dose is missed, give it when remembered unless it is close to the next scheduled dose; in that case, skip the missed dose and resume the regular schedule. Do not give two doses at once. For short postoperative courses, maintain a consistent daily schedule when possible, and consult the clinic if more than one dose has been missed.

Storage and Travel Basics

Store Deramaxx tablets at room temperature in the original, labeled container. Keep dry and protect from excessive heat. Keep out of reach of children and other pets. When traveling, keep your Deramaxx in hand luggage with the prescription label, and carry a few extra tablets in case plans change. A simple pill organizer can help maintain the schedule while away. Medicines are dispensed and labeled by licensed Canadian pharmacies.

Benefits

• Reduces osteoarthritis pain, helping improve mobility and comfort in daily activities.
• Controls postoperative pain after orthopedic or dental procedures.
• COX-2 selectivity designed to target inflammation while aiming to limit gastrointestinal and renal effects compared with some nonselective NSAIDs.
• Chewable, flavored tablets simplify administration and can improve adherence.
• Flexible dosing ranges support individualized treatment plans based on response and tolerance.

Side Effects and Safety

• Common: vomiting, soft stool or diarrhea, reduced appetite, lethargy.
• Less common: increased drinking or urination, constipation, behavioral changes, skin reactions.

Serious but rare risks include stomach or intestinal ulceration and bleeding, kidney or liver injury, and allergic reactions. Signs such as repeated vomiting, black or bloody stools, pale or yellow gums, severe lethargy, or collapse require prompt veterinary assessment. Dogs with concurrent conditions, the very young, and seniors may need closer observation and periodic lab monitoring during NSAID therapy.

Drug Interactions and Cautions

• Avoid combining with other NSAIDs, corticosteroids, or aspirin.
• Use caution with diuretics, ACE inhibitors, anticoagulants, or nephrotoxic drugs; monitoring may be needed.
• Concurrent use with highly protein-bound medicines may increase the potential for adverse effects.
• Ensure adequate hydration and consider periodic lab monitoring during extended therapy.
• Discuss all supplements and over-the-counter products with the clinician before starting therapy.

What to Expect Over Time

Many dogs show greater comfort, smoother movement, and improved participation in daily activities as pain becomes controlled. For osteoarthritis, the goal is steady symptom relief that supports mobility alongside weight management, joint-friendly exercise, and environmental adjustments such as non-slip surfaces and supportive bedding. For surgical pain, Deramaxx is typically used short term to maintain comfort during recovery.

Response to NSAIDs varies. Clinicians often reassess within a reasonable interval to confirm benefit, check for side effects, and decide whether to continue, taper, or switch therapy. Multimodal pain management, including physical rehabilitation or adjunctive medications, may further enhance quality of life.

Compare With Alternatives

Other veterinary NSAIDs your veterinarian may consider include firocoxib and carprofen. Options available from our referral partners include Previcox and Rimadyl. Some cases may also use robenacoxib for dogs (Onsior) for short courses, or meloxicam in select situations based on clinical judgment and patient needs.

Pricing and Access

Canadian pricing and US delivery from Canada can offer meaningful savings versus typical cash-pay rates. Check current pricing, place an order when your veterinarian has issued a valid prescription, and set up refills to stay on track. Our model emphasizes affordability without sacrificing quality or service, and supports pet families seeking reliable access to necessary medications.

Availability and Substitutions

If a requested strength is temporarily unavailable, the veterinarian may recommend a clinically appropriate alternative or dosage plan. Potential substitutes in the same therapeutic class include carprofen or robenacoxib; see Onsior Dog for a short-course option some clinicians prefer after certain procedures. Non-drug measures such as weight control and controlled activity can remain foundational regardless of the NSAID chosen.

Patient Suitability and Cost‑Saving Tips

• Good candidates include adult dogs with confirmed osteoarthritis who tolerate NSAIDs and benefit from improved mobility.
• Not ideal for dogs with active GI ulceration, severe kidney or liver disease, bleeding disorders, or known NSAID allergy.
• Discuss baseline bloodwork before long-term therapy, and periodic rechecks to assess liver and kidney parameters.
• Ask about multi-month prescriptions when stable, which may reduce per-tablet costs and consolidate shipping.
• Coordinate refills ahead of time to avoid treatment gaps; set reminders in your account to keep your schedule on track.
• Some clinicians may consider meloxicam oral liquid in select cases; see Metacam Oral Suspension.
• Combine orders for household pets when appropriate to make the most of one shipment.

Questions to Ask Your Clinician

• Is Deramaxx the best NSAID choice for this dog’s diagnosis and health history?
• What starting dose and duration are planned, and when should re-evaluation occur?
• Which signs of stomach, kidney, or liver trouble should prompt an immediate visit?
• Can gastroprotectants or anti-nausea strategies help if sensitivity occurs? See guidance such as Cerenia Tablets.
• Are there non-drug steps to support joint comfort alongside Deramaxx therapy?
• How should dosing be adjusted if other medicines are added later?
• Would an alternative such as firocoxib or carprofen be preferable in any scenario?

Authoritative Sources

• Deramaxx Product Insert
• FDA CVM NSAIDs for Pets
• AAHA Pain Management

Ready to order Deramaxx for your dog? Place your request with prompt, express, cold-chain shipping and US delivery from Canada through CanadianInsulin’s trusted referral network.

Disclaimer: This material is for general information only and does not replace professional veterinary advice, diagnosis, or treatment. Use prescription medicines only as directed and read the full label and package insert.