Dorzolamide Ophthalmic Solution for Glaucoma and Ocular Hypertension

This prescription eye drop lowers pressure inside the eye to help protect the optic nerve. It treats open-angle glaucoma and ocular hypertension in adults. This page explains safe use, potential side effects, and how to order with US shipping from Canada, including options if you are paying without insurance.

What Dorzolamide Is and How It Works

Dorzolamide Ophthalmic Solution® is a carbonic anhydrase inhibitor eye drop. It reduces aqueous humor production in the ciliary processes, which lowers intraocular pressure. Lower pressure can help slow optic nerve damage in susceptible patients. This medicine can be used alone or with other pressure-lowering drops.

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These dorzolamide eye drops are intended for ophthalmic use only. The solution is not injected or taken by mouth. If you use more than one ocular medication, separate them by a few minutes to avoid washout.

Who It’s For

This treatment is indicated to reduce elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It may be used as initial therapy or added when a single agent does not sufficiently lower pressure. Your clinician may tailor therapy based on the response and tolerance to other agents.

Do not use if you have a known hypersensitivity to sulfonamides or any component of the formulation. People with severe kidney impairment may be at increased risk for systemic effects from topical carbonic anhydrase inhibitors. Contact lens wearers should remove lenses before use because the preservative can be absorbed by soft lenses. For more on the condition it treats, see our overview of Glaucoma and Ocular Hypertension.

Dosage and Usage

Follow your prescriber’s instructions and the official label. Typical adult dosing is one drop in the affected eye or eyes, usually three times daily when used alone. When adding to another agent, your prescriber may adjust the schedule to avoid overlap and to optimize effect.

Administration tips:

• Wash and dry hands before each dose
• Shake gently if directed on the package
• Tilt head back and look up
• Pull down the lower eyelid to form a small pocket
• Hold the bottle tip close to the eye without touching it
• Instill one drop, then close the eye
• Apply gentle pressure to the inner corner of the eye for 1–2 minutes
• Blot excess liquid without rubbing

If you use other drops, wait at least several minutes between products. If you wear soft contact lenses, remove them before use and wait 15 minutes before reinsertion.

For prescription status and ordering needs, you can obtain dorzolamide ophthalmic solution with prescription through your clinician and place an order here. For broader eye care topics, browse Ophthalmology.

Strengths and Forms

The product is supplied as a sterile, preserved solution for topical ocular use. Commonly available strength includes dorzolamide ophthalmic solution 2%. Multi-dose bottles are typically available in small volumes for convenient daily use. Availability can vary by supplier and manufacturer.

Missed Dose and Timing

If you miss a dose, use it when you remember. If it is close to the time for the next dose, skip the missed one and resume your regular schedule. Do not double the dose. Keep a consistent routine to maintain intraocular pressure control.

Storage and Travel Basics

Store at room temperature as directed on the label. Keep the bottle tightly capped and upright when not in use. Do not freeze. Discard if the solution changes color, becomes cloudy, or passes the labeled discard date.

Keep out of reach of children and pets. Avoid touching the dropper tip to the eye, fingers, or any surface to prevent contamination. When traveling, carry your medication in your hand luggage with the original label and a copy of your prescription. An extra bottle may be helpful for extended trips. Temperature-controlled handling when required supports product integrity in transit.

Benefits

This medicine lowers intraocular pressure by reducing fluid production in the eye. It can be used alone if a beta-blocker is not appropriate or as an add-on when further pressure reduction is needed. The treatment is colorless and simple to administer with standard bottle technique.

Side Effects and Safety

Common effects are usually mild and may include:

• Temporary burning or stinging
• Bitter or unusual taste after dosing
• Blurred vision for a short time
• Eye discomfort or dryness
• Eyelid inflammation or redness
• Headache or nausea

Serious reactions are uncommon. Seek medical care for signs of a severe allergic reaction, persistent eye pain, vision changes that do not clear, or symptoms of a sulfonamide reaction such as rash with fever. Contact lens wearers may notice more irritation when lenses are inserted too soon after dosing. Rare corneal changes have been reported, especially in those with prior corneal issues. Report any new or worsening eye symptoms promptly.

Drug Interactions and Cautions

Using other carbonic anhydrase inhibitors by mouth (such as acetazolamide) with this topical agent may increase the risk of systemic effects including acid–base disturbance. Tell your clinician about all medicines and supplements you use. High-dose salicylates and certain diuretics may require extra caution if combined with oral carbonic anhydrase inhibitors. Space other ocular medications several minutes apart to avoid washout and preservative load.

Some patients may benefit from a fixed-combination option that includes a beta-blocker. Ask your clinician whether a dorzolamide plus timolol product like Ophthalmic Solution Cosopt is appropriate in your situation.

What to Expect Over Time

With regular use, eye pressure is managed as part of a long-term treatment plan. You may notice brief stinging or a transient taste after dosing, which often lessens with consistent technique. Keep all follow-up appointments so your clinician can monitor pressure and assess optic nerve health. Adherence to the dosing schedule is key to maintaining stable pressure control.

Compare With Alternatives

Some patients start with a topical beta-blocker or add one if monotherapy is not enough. A branded dorzolamide product such as Trusopt® may be considered if your prescriber specifies it. Another option is a non–carbonic anhydrase inhibitor such as timolol; see our listing for Ophthalmic Solution Timolol and discuss suitability with your clinician.

Pricing and Access

We offer transparent listings so you can review the dorzolamide ophthalmic solution price before placing an order. Orders are processed with Canadian pricing and Ships from Canada to US for eligible addresses. You can compare options and decide what fits your budget and treatment plan.

Checkout is encrypted for your security. If you are looking for seasonal deals, visit our Promotions page for current offerings. Your prescriber’s instructions always determine the appropriate product and quantity.

Ask our team about a dorzolamide ophthalmic solution coupon if you want to explore current manufacturer or pharmacy promotions. Bulk or multi-bottle orders may help reduce per-bottle expense when suitable, subject to your prescription.

Availability and Substitutions

Supply can vary by manufacturer and bottle size. If your preferred version is not available, your prescriber may recommend a suitable alternative in the same class or another class that lowers eye pressure. Options in other classes include prostaglandin analogs; for example, you can review Ophthalmic Solution Vyzulta as one of several possibilities.

Patient Suitability and Cost-Saving Tips

Good candidates are patients diagnosed with open-angle glaucoma or ocular hypertension who need pressure reduction. Those with a sulfonamide allergy, severe renal impairment, or significant corneal disease may need other options. Discuss pregnancy or breastfeeding with your clinician before starting any ocular therapy.

To manage costs, consider multi-month fills if your prescription allows, and set refill reminders to avoid lapses. Buying a second bottle for travel can prevent missed doses when you are away from home. For adjunctive therapy questions or alternative classes, review options like Ophthalmic Solution Alphagan or Lumigan RC with your prescriber.

Questions to Ask Your Clinician

• Is this drop appropriate for my type of glaucoma?
• How should I space it with my other eye medications?
• What signs mean I should contact the clinic right away?
• Could a fixed-combination drop reduce my dosing frequency?
• How often should my eye pressure and optic nerve be checked?
• Are there options if I experience stinging or taste changes?

Authoritative Sources

For official prescribing details, see the FDA DailyMed label for dorzolamide ophthalmic solution: FDA DailyMed Dorzolamide.

Health Canada’s Drug Product Database provides Canadian regulatory information on ophthalmic dorzolamide products: Health Canada DPD.

For brand reference, consult the manufacturer information for Trusopt from Merck, which contains class-specific safety details: Merck Trusopt Prescribing Info.

Ready to proceed? You can order from CanadianInsulin with prompt, express, temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.