Eliquis® Tablets for Atrial Fibrillation

This anticoagulant is used to lower the risk of dangerous clots. Here you can review uses, dosing, side effects, and access options, with US delivery from Canada and guidance on your price without insurance.

What Eliquis Is and How It Works

Eliquis® (apixaban) is an oral direct factor Xa inhibitor. It reduces thrombin generation, which helps prevent clot formation in veins and the heart. The medicine is approved for several uses where preventing or treating clots is important.

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Mechanistically, apixaban limits the conversion of prothrombin to thrombin by inhibiting factor Xa. This action lowers the chance that fibrin-rich clots will form or grow. It can be used long term when the benefit of reducing clot-related events outweighs bleeding risks, as judged by a healthcare professional.

Who It’s For

This treatment is indicated to reduce the risk of stroke and systemic embolism in nonvalvular atrial fibrillation. It is also used for the treatment of deep vein thrombosis and pulmonary embolism, and to reduce the risk of recurrent DVT and PE after initial therapy. In addition, it is used to prevent DVT after hip or knee replacement surgery.

People with active pathological bleeding should not use this medicine. Those with severe hypersensitivity to apixaban should avoid it. Use requires caution in significant liver disease, advanced kidney impairment, or with conditions that raise bleeding risk. It is generally not recommended for patients with mechanical heart valves. For condition overviews, see Atrial Fibrillation and Deep Vein Thrombosis.

Dosage and Usage

Tablets are taken by mouth, typically twice daily. The prescribed schedule depends on the indication and on clinical factors such as kidney function, age, and body weight. Take doses consistently, with or without food, unless your prescriber advises otherwise. Swallow tablets with water. The treatment course can be short after surgery, extended for venous clots, or chronic in atrial fibrillation per the approved label.

If you are transitioning from or to another anticoagulant, your clinician will determine timing to maintain protection while minimizing overlap. Before dental work or surgical procedures, therapy may need temporary interruption to reduce bleeding risk. Decisions about interruptions and restarts should follow the official label and your clinician’s guidance.

Strengths and Forms

This product is supplied as film-coated oral tablets. Commonly available strengths include 2.5 mg and 5 mg. Availability may vary by pharmacy and country.

Eliquis 5 mg tablets are a standard presentation; the lower strength supports patients who need a reduced dose. Colors, shapes, and imprint details differ by strength, helping distinguish them. Pack sizes and refill intervals vary by prescription.

Missed Dose and Timing

If a dose is missed, take it as soon as you remember on the same day. Then resume the regular twice-daily schedule. Do not double up doses at one time to make up for a missed tablet. Consistent timing helps maintain steady anticoagulant effect.

If you miss multiple doses, speak with your prescriber for specific advice based on your indication and risk. Always consult the official prescribing information for detailed instructions.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excessive heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Carry your medication in the original labeled container when you travel. You can pack it in a carry-on so agents can verify your name and prescription.

For trips, bring a copy of your prescription and enough supply for the full journey plus a buffer. Avoid storing tablets in a hot car or damp bathroom. If you have questions about storage during travel, you can message our team after you place your order for practical tips.

Benefits

This therapy helps lower the risk of stroke in eligible people with nonvalvular atrial fibrillation. It treats blood clots in the legs and lungs and helps prevent recurrence after initial therapy. Many patients value oral dosing and that routine INR monitoring is not required. The class has fewer known food interactions than some older options, which can simplify daily routines.

The treatment can be continued long term when benefits outweigh bleeding risks. It may be combined with other therapies for short periods after certain procedures, according to the label and clinician judgment.

Side Effects and Safety

• Bruising or minor bleeding
• Nosebleeds or bleeding gums
• Anemia-related symptoms such as fatigue
• Nausea or stomach discomfort
• Minor cuts that take longer to stop bleeding
• Headache or dizziness

Serious risks include major bleeding, which may present as black stools, coughing blood, vomiting blood, severe headache, or sudden weakness. Rarely, spinal or epidural hematomas can occur in patients receiving neuraxial anesthesia or spinal puncture. Hypersensitivity reactions are uncommon but possible. For insulin or sulfonylurea users, hypoglycemia is not a class issue here; however, patients on antiplatelets or other anticoagulants have additive bleeding risk.

Drug Interactions and Cautions

Strong dual inhibitors of CYP3A4 and P-glycoprotein, such as ketoconazole, itraconazole, ritonavir, or clarithromycin, can raise exposure. Strong inducers such as rifampin, carbamazepine, phenytoin, or St. John’s wort can reduce exposure and effect. Combining with other anticoagulants or antiplatelets increases bleeding risk. NSAIDs can also increase bleeding risk.

Use requires caution in moderate to severe hepatic impairment or advanced renal impairment. Older age, low body weight, and certain lab values may influence the prescribed dose. If you receive spinal or epidural anesthesia, discuss timing to lower the risk of a hematoma.

What to Expect Over Time

Effect begins with consistent dosing, aiming to prevent new clots and limit growth of existing ones. The plan may be time-limited for postoperative prophylaxis or extended for venous clots, and it is often chronic in atrial fibrillation. Most patients do not need routine coagulation testing, but periodic clinical follow-up is standard. Adherence is important; set reminders and use a weekly pill organizer if advised by your clinician.

Discuss any planned procedures or new medicines in advance. If therapy must be paused, your team will determine when to resume.

Compare With Alternatives

Several approved oral anticoagulants may be appropriate alternatives depending on clinical factors. Rivaroxaban is available as Xarelto. Dabigatran is available as Pradaxa. These options differ in dosing frequency, kidney considerations, and capsule or tablet form. Your prescriber will choose based on indication, bleeding risk, renal function, and co-medications.

Pricing and Access

Check current listings to compare options and see typical savings versus local pharmacy cash rates. Order Eliquis online when you have a valid prescription, and track payment methods during checkout. We display both brand apixaban price context and options for longer supplies to improve convenience. For context, Apixaban cash price varies by strength and quantity.

Our listings reflect Canadian pharmacy sourcing and fulfillment. Ships from Canada to US with clear status updates. You can review current pricing, then upload your prescription and proceed through our encrypted checkout. For broader comparison content, see Save On Apixaban Cost.

Availability and Substitutions

Supply can vary by strength and manufacturer. If a specific package is unavailable, a prescriber may recommend a clinically appropriate alternative or different pack size. Listings reflect Eliquis Canadian pricing when stock is available. We do not guarantee restock dates, but we update availability as we receive changes from dispensing pharmacies.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who need oral anticoagulation and can adhere to a twice-daily schedule. It may not suit people with active bleeding, severe hypersensitivity to apixaban, or those with very high bleeding risk. Patients with significant renal or hepatic impairment require careful evaluation. If you have a history of frequent falls, ulcer disease, or recent bleeding, clinicians may weigh risks differently.

For budgeting, consider multi-month fills when appropriate, such as a 90-day supply. Refill reminders and calendar alerts help maintain continuity. Comparing options by dose can clarify value; Apixaban 2.5 mg price may differ from other strengths. Discuss generics and therapeutic alternatives with your clinician if cost is a barrier. You can store extra supply properly and plan ahead for travel or procedures.

Questions to Ask Your Clinician

• Which indication am I using this anticoagulant for?
• How long is therapy expected for my condition?
• What signs of bleeding should prompt urgent evaluation?
• Which medicines or supplements should I avoid while on apixaban?
• Do I need to pause therapy before dental work or surgery?
• Would a different oral anticoagulant be safer for my kidney or liver status?
• Can I use a 90-day supply to reduce pharmacy visits?

Authoritative Sources

Manufacturer Prescribing Information

DailyMed Drug Labeling

Health Canada Drug Product Database

For broader education, see What Is Eliquis Used For and explore Heart Health Medications for related therapies.

Ready to proceed? Submit your prescription and place an order with US shipping from Canada and prompt shipping. Information on this page is educational and not a substitute for professional medical advice; always follow the official label and your prescriber’s directions.