Humulin® 30/70 Vial for Premixed Insulin Therapy

Humulin® 30/70 is a premixed human insulin for people who need both mealtime and between‑meal coverage in a simpler injection schedule. Many choose this vial presentation for steady, predictable dosing at breakfast and dinner. With US delivery from Canada, patients access Canadian pricing with prompt, express, cold‑chain shipping; some pay cash without insurance when working with a verified prescription.

What Humulin® Is and How It Works

Humulin® 30/70 combines two human insulins in one vial: a short‑acting component for meals and an intermediate‑acting component for background coverage between meals and overnight. The short‑acting portion helps limit post‑meal glucose rises, while the intermediate component slows absorption and extends activity for sustained control. This premix can reduce the number of daily injections for patients who would otherwise draw up and mix separate vials.

Every CanadianInsulin order is prescription‑checked with your clinic and dispensed by a licensed Canadian pharmacy. The medicine is delivered as a suspension; it should appear uniformly cloudy after gentle mixing before each dose. Patients typically take it before a meal so the short‑acting portion is active as food is absorbed, while the intermediate portion helps cover the upcoming hours.

Care teams often choose a premix when a consistent meal pattern is expected and simpler timing is preferred. Because both components are fixed in one product, dose adjustments usually focus on timing and total units rather than changing the ratio. Some patients pay cash without insurance; a valid prescription is still required.

Who Humulin® Is For

This premixed insulin is prescribed for adults with type 1 or type 2 diabetes who need both mealtime and basal coverage and can follow a consistent meal schedule. It is also used in some adolescents when a premix suits the treatment plan. It is not appropriate for treatment of diabetic ketoacidosis or for intravenous use.

Use with caution in patients with kidney or liver impairment, those at risk for hypoglycemia, and people with variable food intake. Pregnancy and breastfeeding decisions should be guided by standard insulin use in these periods and individualized by a clinician. Anyone with a history of severe allergic reactions to human insulin or formulation components should avoid this product.

Dosage and Usage

Dosing is individualized. Many patients start with twice‑daily injections given shortly before breakfast and the evening meal, then titrate based on glucose patterns. Clinicians may adjust morning and evening doses separately to address pre‑lunch, pre‑dinner, and fasting readings.

General administration steps for vials:

• Wash hands and gather supplies, including a U‑100 insulin syringe.
• Roll the vial gently between the palms until the suspension looks uniformly cloudy; do not shake vigorously.
• Clean the rubber stopper with alcohol.
• Draw air into the syringe equal to the prescribed units; inject air into the vial.
• Invert the vial and draw the dose; tap out bubbles and verify units at eye level.
• Inject subcutaneously in the abdomen, thigh, buttock, or upper arm. Rotate sites to reduce irritation.

Do not use if clumps, particles, or frosty deposits are present after mixing, or if the liquid remains clear. Do not share syringes. For detailed titration plans, clinicians typically review glucose logs and A1C and may adjust by small increments to target pre‑meal and fasting goals safely.

For education on premixes and how they fit into therapy, see Premixed Insulin and dosing context in Insulin Dosage Chart.

Strengths and Forms

Common presentations include U‑100, 10 mL multidose vials. Availability can vary by pharmacy and region.

Missed Dose and Timing

If a scheduled dose is missed near a meal, individualized guidance applies. In general, taking the dose too close to the next meal or doubling up increases hypoglycemia risk. Patients are usually instructed to check glucose, resume the regular schedule with the next appropriate meal dose, and contact their care team for persistent pattern issues. Skipped meals after dosing increase low‑glucose risk; consistent meal timing is important with premixed regimens.

Storage and Travel Basics

Unopened vials are typically stored refrigerated and never frozen. Once in use, many labels allow storage at room temperature for a limited period; follow the product insert for exact timelines. Protect from direct heat and light, and keep the cap on when not in use. When traveling, keep your vial and syringes in an insulated case with cool packs separated by a barrier to avoid freezing.

Temperature‑sensitive items ship with cold‑chain handling and insulated packaging. For at‑home storage, place insulin in the main refrigerator compartment, not the door, to reduce temperature swings. When away from home, keep your supplies in carry‑on baggage and bring a travel letter if needed for security screening.

Pen Handling and Sharps Disposal

This product is used with syringes. Use a new sterile needle for each injection, and never share syringes or needles. Dispose of used sharps in an approved sharps container; when full, follow local drop‑off or mail‑back programs. Do not throw loose needles in household trash or recycling.

Benefits

Key benefits of a premixed human insulin include:

• Simplified regimen with combined mealtime and between‑meal coverage in one vial.
• Predictable onset and duration that fit regular breakfast and dinner schedules.
• Fewer daily injections compared with drawing and mixing separate insulins.
• Broad clinical familiarity and a long safety history for human insulin premixes.

For some patients, a premix supports adherence and stable routines. When meal timing or carbohydrate intake is highly variable, a different regimen may be preferred.

Side Effects and Safety

• Common: low blood sugar (shakiness, sweating, fast heartbeat, dizziness), injection‑site redness or thickening, mild edema, and weight gain.
• Less common: allergic rash or itching, lipodystrophy at injection sites.

Serious risks include severe hypoglycemia, hypokalemia, and rare systemic allergy. Hypoglycemia risk increases with missed or delayed meals, excessive dosing, increased activity, alcohol use, or kidney/liver impairment. Concomitant insulin secretagogues (such as sulfonylureas) can further raise the risk of low glucose. Seek urgent care for severe or persistent symptoms suggestive of a serious allergic reaction or very low blood sugar.

For more on adverse effects, see the overview in Humulin Side Effects.

Drug Interactions and Cautions

Medicines that may increase insulin effect and hypoglycemia risk include ACE inhibitors, ARBs, certain antidepressants, salicylates, and alcohol. Agents that may raise glucose and increase dose requirements include corticosteroids, some atypical antipsychotics, and certain hormonal therapies. Beta blockers may blunt hypoglycemia warning symptoms. Thiazolidinediones may cause fluid retention; monitor for heart failure symptoms when used together.

Use care with any change in diet, activity, or concurrent medications, as insulin needs can shift quickly. Patients with frequent lows, erratic meals, or advanced kidney disease often require closer supervision and smaller titration steps.

What to Expect Over Time

After initiation or dose changes, fasting and pre‑meal glucose readings guide adjustments. Over weeks, dose refinements target stable pre‑breakfast and pre‑dinner numbers with fewer symptomatic lows. Hemoglobin A1C generally reflects the cumulative effect across multiple months. Many patients remain on a stable twice‑daily dose once meal timing is consistent and patterns are predictable.

Compare With Alternatives

Other premixed human insulins with similar intent include Novolin GE 30 70. Patients wanting a cartridge presentation for use with compatible pens may consider Humulin 30 70 Cartridges. For plans that separate basal and bolus dosing, short‑acting human insulin is an option; see Humulin R 100u.

Explainers on onset and duration can help compare options, including background therapy with NPH in Novolin GE NPH Vials.

Pricing and Access

CanadianInsulin connects patients with licensed Canadian pharmacies, enabling US delivery from Canada and access to Canadian pricing. Many customers see meaningful cash‑pay savings compared with typical US retail. Create an account to upload a valid prescription and place an order. A refill request can be submitted from your account when it is time for the next supply.

For additional savings opportunities and periodic offers, visit our promotions page. For more vial options, browse Insulin Vials.

Availability and Substitutions

Supply can vary. If a specific presentation is unavailable, a prescriber may recommend a suitable alternative premix or an equivalent human insulin regimen. Pharmacy teams dispense only with a valid prescription and may contact the clinic for therapeutic confirmation if a substitution is proposed.

Patient Suitability and Cost‑Saving Tips

Good candidates include adults with type 1 or type 2 diabetes who have regular meal patterns and would benefit from fewer injections. Those with frequent hypoglycemia, highly variable schedules, or gastroparesis may be better served by flexible basal‑bolus plans or alternate mixes. Injection technique, site rotation, and consistent carbohydrate intake are important for stable results.

• Consider multi‑month quantities to reduce shipping frequency and help maintain continuity of therapy.
• Align refills with clinic follow‑ups so dose changes and supply needs are coordinated.
• Set account reminders so you can request your next shipment before running low.
• Keep backup syringes, alcohol wipes, and a spare vial stored properly for travel.

Questions to Ask Your Clinician

• How should morning and evening doses be adjusted based on my glucose log?
• What is the best injection site rotation plan for my body type and activity?
• What actions should I take if pre‑meal glucose is low or if a meal will be delayed?
• Would a premix remain appropriate if my work schedule or diet changes?
• Could a separate basal‑bolus plan or a different premix improve control or flexibility?
• What warning signs suggest my dose is too high or too low?

Authoritative Sources

• Humulin 70/30 Prescribing Information (Eli Lilly)
• FDA Labeling for Human Insulin Mix
• Health Canada Product Monograph

Ready to proceed? Place an order with CanadianInsulin for US delivery from Canada and Canadian pricing, supported by prompt, express, cold‑chain shipping.

Disclaimer: This information is educational and not a substitute for professional medical advice. Prescribers determine diagnosis, appropriateness, and dosing for each individual.