Humulin® 30/70 Vial for Diabetes

Humulin® 30/70 Vial is a premixed human insulin that contains 70% isophane (NPH) and 30% regular insulin at U-100 strength. This page explains what it is, how it works, and how to use it safely. CanadianInsulin provides Canadian pricing and ships from Canada to the US, so your order arrives in the US from Canada with prompt, express, cold-chain shipping. You can buy online without insurance.

CanadianInsulin connects patients with licensed Canadian pharmacies. Prescriptions are verified with your clinic before dispensing.

What Humulin® Is and How It Works

Humulin® 30/70 is a biphasic, premixed insulin made of intermediate-acting NPH and short-acting Regular insulin. The Regular component helps manage the rise in blood sugar around meals. The NPH component provides basal coverage between meals and overnight. This combination can simplify therapy by using fewer injections than separate basal and mealtime insulins.

Humulin 30/70 starts working before the meal when taken as directed and continues to act for many hours. Timing and effect vary by person, dose, injection site, and activity level. For an overview of how premixed insulins behave, see our Premixed Insulin Guide.

Who Humulin® Is For

Humulin 30/70 is used to improve glycemic control in adults and children with diabetes who require insulin. It may be prescribed for Type 1 diabetes and for Type 2 diabetes when diet, exercise, and oral or non-insulin injectable medicines are not enough. Visit our category for Type 2 Diabetes to explore related therapies.

Humulin 30/70 is not for treatment of diabetic ketoacidosis and is not designed for insulin pumps. People with recurrent severe hypoglycemia or hypokalemia require careful evaluation before use. Those with known insulin allergies need clinician guidance.

Dosage and Usage

Dosing is individualized. Clinicians typically direct subcutaneous injections once or twice daily, often around breakfast and the evening meal. Many patients take Humulin 30/70 approximately 30 minutes before eating. Your healthcare provider determines the total daily units and how to divide the doses.

General use points:

• Inject subcutaneously in the abdomen, thigh, upper arm, or buttocks. Rotate sites to reduce lipodystrophy.
• Never inject into a vein or muscle.
• Adjustments may be needed with changes in meal patterns, activity, weight, stress, or other medicines.
• If switching from another insulin, follow your prescriber’s plan and monitor glucose closely during the transition.

Always follow the product insert and your clinician’s instructions.

Strengths and Forms

Common presentations include:

• U-100 (100 units/mL) in a 10 mL multidose vial
• Other presentations (such as 3 mL cartridges) may exist; availability can vary by pharmacy and region.

See more vial options across our Insulin Vials category.

Missed Dose and Timing

If a dose is missed, the general approach is to consider how close it is to the next scheduled dose and whether food is available. Many clinicians advise taking the missed dose when remembered if it is not too close to the next injection and a meal is planned, otherwise skipping it. Do not double doses. Monitor glucose and follow the plan your clinician provides.

Storage and Travel Basics

Unopened vials are typically stored in a refrigerator. Do not freeze. Protect from direct heat and light. Once in use, many labels allow storage at room temperature for a limited time; confirm the specific in-use time in the patient insert. Keep vials away from extreme temperatures.

For travel, use an insulated bag with a cool pack. Do not place the vial directly on ice or near a heating source. Carry supplies in hand luggage if flying. Keep a backup plan for power outages or delays.

Pen Handling and Sharps Disposal

This product is a vial, not a pen. Use only U-100 insulin syringes. Resuspend the insulin before each dose by gently rolling the vial between the palms and inverting it until the suspension looks uniformly milky. Do not use if clumps remain or if the liquid stays clear.

• Use a new sterile needle and syringe for each injection.
• Do not share needles or syringes.
• Dispose of used sharps in a puncture-resistant, FDA-cleared sharps container or a sturdy household alternative per local rules.

Benefits

Humulin 30/70 provides both mealtime and between-meal insulin action in one injection. This can simplify therapy compared with separate basal and bolus dosing. The U-100 vial format works with widely available U-100 syringes. Many patients appreciate a consistent schedule tied to meals, which can support routine and adherence.

Side Effects and Safety

The most common side effect of insulin therapy is hypoglycemia. Signs can include shakiness, sweating, fast heartbeat, headache, hunger, or confusion. Mild low blood sugar is typically managed per your clinician’s plan, often with fast-acting carbohydrates.

• Injection site reactions such as redness, itching, or swelling
• Weight gain
• Edema (fluid retention)
• Skin changes at the injection site (lipodystrophy)
• Rash or pruritus

Serious effects can include severe hypoglycemia, hypokalemia, and rare systemic allergic reactions. Fluid retention and heart failure can occur when insulin is used with thiazolidinediones. Seek urgent care for severe reactions. For a deeper dive into safety topics, read Humulin® Side Effects.

Drug Interactions and Cautions

Many medicines can raise or lower blood glucose or change insulin needs. Clinicians often recheck doses when new medicines start or stop.

• Drugs that may increase glucose and insulin needs: corticosteroids, some diuretics, sympathomimetics, certain antipsychotics, thyroid hormones.
• Drugs that may increase insulin effect or hypoglycemia risk: ACE inhibitors, ARBs, salicylates, some antidepressants, alcohol.
• Beta-blockers can mask some symptoms of hypoglycemia.
• GLP-1 or SGLT2 therapies may change insulin requirements; monitor per care plan.
• Using thiazolidinediones with insulin may cause edema or worsen heart failure.

Do not mix Humulin 30/70 with other insulins in the same syringe. Humulin 30/70 is not for use in insulin pumps.

What to Expect Over Time

With consistent use, many patients see smoother pre-meal and between-meal readings. A1C changes reflect average glucose over months, so improvements show gradually as the dose is refined. Routine self-monitoring and follow-up help fine-tune dose timing and amounts. Illness, travel, or major lifestyle changes may prompt temporary adjustments.

Compare With Alternatives

Other premixed insulins may be appropriate if Humulin 30/70 is not a fit. A human insulin alternative is Novolin® GE 30/70 Vials, which your prescriber may consider based on clinical goals and availability. An insulin analog premix option is NovoMix® 30 Penfill, which contains insulin aspart components with different onset and peak characteristics. Another approach is using separate basal (NPH) and short-acting (Regular) insulins for more individualized adjustments, guided by your clinician.

Pricing and Access

Humulin 30/70 Vial is available with Canadian pricing and US delivery from Canada. Many patients paying cash find meaningful cost differences compared with local retail. Review the current Humulin 30/70 Vial price and place an order online. Self-pay and cash price options are supported.

See current pricing and any limited-time offers on our Promotions page. Checkout is encrypted for security.

Availability and Substitutions

Availability can vary. If Humulin 30/70 is temporarily unavailable, a prescriber may recommend a clinically suitable alternative. Pharmacy teams dispense the exact medicine written on the prescription unless your clinician authorizes a substitution.

Patient Suitability and Cost Saving Tips

Humulin 30/70 may be appropriate for patients who benefit from a structured schedule aligned to regular meals. Those with highly variable meal timing, frequent hypoglycemia, or who require very fine mealtime adjustments may need a different regimen.

• Ask about multi-month quantities to reduce per-fill costs and ensure steady supply.
• Vials can be cost-effective for those comfortable using syringes.
• Set refill reminders before running low, especially before travel or holidays.
• Share your meter data at follow-up visits to optimize dosing.

Questions to Ask Your Clinician

• Is Humulin 30/70 the best fit for my meal schedule and activity?
• What starting dose and timing should I use before meals?
• How should I adjust for higher or lower readings on my plan?
• What are the signs of low blood sugar I should watch for?
• Which syringes and needle sizes are appropriate for me?
• What should I do when I am ill or skipping a meal?
• If Humulin 30/70 is not available, which alternative do you recommend?

Authoritative Sources

Eli Lilly Canada

FDA DailyMed

Health Canada Drug Product Database

Start your order for Humulin 30/70 Vial with US delivery from Canada and prompt, express, cold-chain shipping.