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Levetiracetam
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Levetiracetam is an anticonvulsant medication used to treat partial-onset seizures, myoclonic seizures, and generalized tonic-clonic seizures in both adults and children. It works by stabilizing electrical activity in the brain to prevent seizure episodes.
Benefits:
- Effective seizure control across multiple seizure types
- Suitable for use as monotherapy or in combination with other antiepileptics
- Minimal drug interactions
- Available in oral and injectable forms for flexible treatment
Dosage:
- Adult initial dose: 500 mg twice daily
- Maintenance dose: Up to 3000 mg/day, depending on response
- Pediatric dosing based on weight
- Dosage adjustments may be needed for kidney impairment
Warnings and Precautions:
- May cause mood changes or behavioral symptoms
- Monitor for signs of depression or suicidal thoughts
- Use with caution in patients with renal dysfunction
- Gradual withdrawal recommended to prevent seizure recurrence
Usage Instructions:
- Take at the same time daily with or without food
- Swallow tablets whole with water
- Do not abruptly stop without medical guidance
- Follow the prescribed dosing schedule strictly
Storage Information:
- Store at room temperature (15–30°C)
- Keep in a dry place, away from direct sunlight
- Keep out of reach of children
Common Side Effects:
- Drowsiness
- Dizziness
- Fatigue
- Irritability or aggression
- Loss of appetite
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What is Levetiracetam used to treat?
Levetiracetam is an antiepileptic drug used to treat partial-onset, myoclonic, and generalized tonic-clonic seizures. It is approved for both adults and children and is often used as an adjunctive therapy.
How does Levetiracetam work?
Though its exact mechanism is not fully understood, Levetiracetam is believed to modulate neurotransmitter release through binding to synaptic vesicle protein SV2A. This helps stabilize electrical activity in the brain and prevent seizure occurrence.
Can Levetiracetam be stopped suddenly?
No, stopping the medication abruptly can trigger seizure recurrence or status epilepticus. Dosage must be tapered gradually under a doctor’s supervision to avoid withdrawal symptoms and ensure safety.
What are common side effects of Levetiracetam?
Side effects may include dizziness, fatigue, mood swings, and irritability. Some patients may also experience behavioral changes such as aggression or depression, which should be reported promptly.
Is Levetiracetam safe for long-term use?
Yes, it is generally well tolerated for long-term use in managing epilepsy. Regular monitoring by a neurologist is important to assess effectiveness and manage any potential side effects over time.
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