Procytox® for Dogs and Cats

Procytox is cyclophosphamide, a chemotherapy medicine for dogs and cats. Veterinarians use it to treat lymphoma and other cancers. This guide explains how it works, safety basics, and how to access Canadian pricing with US delivery from Canada. You can also review estimated cost without insurance and compare options.

What Procytox® Is and How It Works

Procytox® contains cyclophosphamide, an alkylating agent. It is a prodrug that becomes active in the liver. The active metabolites bind to DNA and disrupt cancer cell growth. This slows or stops cell division in rapidly dividing tissues. Procytox is widely used in multi-drug protocols for canine and feline cancers.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.

In dogs and cats, clinicians often include cyclophosphamide in combination regimens. A common example is CHOP, which may pair cyclophosphamide with drugs such as vincristine and doxorubicin plus a corticosteroid. Your oncology team selects the schedule and dose based on diagnosis and current bloodwork.

Beyond oncology, veterinarians sometimes use cyclophosphamide for immune-mediated conditions when appropriate. These uses are at a veterinarian’s discretion and require close monitoring.

Who Procytox® Is For

Procytox may be prescribed for dogs or cats diagnosed with lymphoma. It can also be part of therapy for certain sarcomas, mast cell tumors, and mammary or nasal tumors, as determined by your veterinarian. Some specialists consider it for immune-mediated disease control in select pets.

It is not suitable for pregnant or nursing animals. Pets with severe bone marrow suppression, active severe infections, or bleeding in the urinary tract should generally avoid cyclophosphamide. Your veterinarian will review recent lab results and medical history before use.

Dosage and Usage

Veterinarians tailor dosing by weight, body surface area, and protocol. Cyclophosphamide may be given as short daily courses over several days, or as single doses at set intervals. It is commonly used with other agents. For example, CHOP protocols can include cyclophosphamide with Vincristine and Doxorubicin, plus a steroid such as prednisone.

Many pets receive oral tablets at home. Give doses exactly as directed. Your veterinarian may recommend morning dosing and strong hydration. Frequent opportunities to urinate can help reduce bladder exposure to irritating metabolites. If a clinic gives cyclophosphamide by injection, the team will handle dosing and monitoring during visits.

Tablets can be given with food if your veterinarian agrees. Do not crush or split tablets unless your vet instructs you. Wear disposable gloves when handling tablets or cleaning up bodily fluids within 48 hours after dosing. Wash hands after giving the medicine.

Veterinarians check complete blood counts on a schedule. Lab timing helps guide when to give the next dose or when to hold treatment. Follow your clinic’s instructions closely and keep all recheck appointments.

Strengths and Forms

Common presentations include:

• Oral tablets: 25 mg and 50 mg are widely referenced.
• Powder for injection: 200 mg, 500 mg, and 1 g vials are commonly listed.

Availability can vary by supplier and country labeling. Your veterinarian and dispensing pharmacy will confirm the exact product and strength.

Missed Dose and Timing

If you miss a tablet dose, give it when remembered unless it is close to the next scheduled dose. If timing is uncertain, contact your clinic for advice. Do not double up to make up for a missed dose. If your pet vomits soon after a dose, ask your veterinarian whether to redose.

For cycle-based chemotherapy, the clinic sets specific treatment days. If your pet cannot receive a planned dose due to low blood counts or illness, the team will adjust the schedule.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from light and moisture. Keep the container tightly closed and out of reach of children and other pets. Do not store in a bathroom. For injection vials, the clinic or pharmacy will manage storage and handling.

When traveling with tablets, keep them in the original labeled container. Protect from extreme heat or cold. Pack gloves and a sealable bag for safe handling. If traveling by air, carry the medication in your hand luggage with the label.

Benefits

Procytox helps control cancer growth by disrupting tumor cell replication. It is a key component in many proven veterinary protocols. Tablets allow treatment at home for parts of a protocol, reducing some clinic visits. In certain cases, clinicians use cyclophosphamide to modulate the immune system.

When used correctly, benefits include tumor shrinkage, delayed progression, and improved comfort in many pets. Outcomes depend on tumor type, stage, overall health, and the full treatment plan.

Side Effects and Safety

• Lowered white blood cell count
• Reduced appetite
• Vomiting or nausea
• Diarrhea or soft stools
• Lethargy or weakness
• Increased thirst or urination
• Hair thinning in some breeds

Serious but less common risks include sterile hemorrhagic cystitis, seen as blood in urine, straining, or frequent urination. Immediate evaluation is needed if these occur. Severe bone marrow suppression can lead to infection risk or bleeding. Liver or heart effects are rare with routine veterinary dosing but have been reported. Call your clinic if you notice fever, bruising, persistent vomiting, or any concerning change.

Your vet may recommend strategies to reduce bladder irritation, such as strong hydration, frequent outdoor breaks, and morning dosing. Report any urinary changes promptly. Some protocols use drug-free rest days to support blood count recovery.

For nausea control, your veterinarian may prescribe supportive therapy. Many clinics use maropitant; see our guide to Cerenia Tablets for more information about this option.

Drug Interactions and Cautions

Using other bone marrow–suppressing drugs at the same time can increase risk for low blood counts. Phenobarbital and other enzyme-inducing medicines may alter cyclophosphamide metabolism. Chloramphenicol and other enzyme inhibitors may also affect exposure. Avoid live vaccines during chemotherapy. Tell your veterinarian about all medicines, supplements, and preventives your pet takes, including recent steroids and antibiotics.

Use caution in pets with liver or kidney impairment. Extra monitoring may be required in senior animals. Pregnant people or those trying to conceive should avoid handling this drug and pet waste for 48 hours after dosing. Wear gloves and wash hands after any contact.

What to Expect Over Time

With effective therapy, some pets show reduced lymph node size or improved comfort within weeks. Others require several cycles. Bloodwork guides each step. Side effects may ebb and flow with dosing. Your veterinarian will discuss goals, such as remission, disease control, or palliation, and adjust the plan as needed.

Expect regular check-ins for physical exams and lab tests. Your clinic may schedule re-staging imaging at set milestones. If side effects occur, dose timing, supportive care, or drug choices may change to keep treatment safe.

Compare With Alternatives

For certain mast cell tumors in dogs, toceranib can be an option. You can review Palladia® with your veterinarian when appropriate. For some small cell lymphomas, especially in cats, chlorambucil is frequently used. See Leukeran® to learn about that choice.

Your oncology team will recommend the best plan for your pet’s diagnosis and health status.

Pricing and Access

Check Canadian pricing for Procytox and arrange US shipping from Canada. You can view the current Procytox price and compare the Procytox cost to similar therapies. If your vet prescribes it, you can buy Procytox online through a secure checkout. Our checkout is encrypted for your privacy.

For broader context on pet medication options and savings, you can read our guide on Buy Pet Medications. If you need other pet therapies, browse our Pet Medications section.

Availability and Substitutions

Supply can vary by strength and form. If a specific Procytox product is unavailable, your veterinarian may recommend an alternative strength, a compounded option, or a different agent from the same class. Final decisions depend on your pet’s diagnosis and current lab results.

Patient Suitability and Cost Saving Tips

Pets most likely to benefit are those with cancers where cyclophosphamide is part of standard protocols. Pets with severe marrow suppression, active bleeding disorders, or urinary tract issues may not be candidates. Discuss breed-specific sensitivities, existing medications, and home environment with your veterinarian.

To help manage costs and adherence:

• Ask your veterinarian about multi-month supplies when appropriate.
• Use refill reminders so you never miss a cycle.
• Group lab visits and rechecks to reduce extra trips.
• Discuss generic versus brand options if your prescriber allows.
• Maintain a medication log to track dosing days and any side effects.

Questions to Ask Your Clinician

• What is the treatment goal for my pet’s cancer?
• How will you monitor blood counts and adjust dosing?
• Which side effects need an urgent call versus routine reporting?
• Should I give doses in the morning, and how much should my pet drink?
• What supportive medicines help with nausea or diarrhea?
• How will this interact with my pet’s current medications?
• If Procytox is not available, what is the next best option?

Authoritative Sources

FDA DailyMed: Cyclophosphamide Tablets

Health Canada Drug Product Database

FDALabel: Cyclophosphamide

Start your order to access Canadian pricing with US delivery from Canada. Always follow your veterinarian’s directions and the official label.