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Retatrutide

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Description

Uses of Retatrutide

Retatrutide is a triple hormone receptor agonist targeting GIP (gastric inhibitory peptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors. It is currently under development for the treatment of obesity and type 2 diabetes mellitus. By targeting these hunger-regulating hormones, Retatrutide promotes weight loss and improves cardiometabolic health. 

Precautions and Warnings

Retatrutide’s safety profile is consistent with other incretin-based therapies. The most common side effects are gastrointestinal in nature, such as nausea and diarrhea, particularly during the dose-escalation phase. It should be used with caution in individuals with a history of severe gastrointestinal issues or pancreatitis. Patients should inform their healthcare provider of any pre-existing conditions.

Dosage

Retatrutide is administered as a subcutaneous injection once weekly, with doses of 1 mg, 4 mg, 8 mg, and 12 mg. The initial dosing starts at either 2 mg or 4 mg, depending on the regimen. Treatment duration in clinical trials has typically spanned 48 weeks or longer, and the dosing may be modified according to the individual’s response and tolerance. A healthcare provider will decide on the optimal dosage.

Side Effects

Common side effects:
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Low blood sugar (hypoglycemia) in diabetes patients
  • Headache
  • Fatigue 

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Filter by Categories
Announcement
Arthritis
Cancer
Diabetes
Diabetes in Pets
Diabetes Supplies
Diabetes Tests
Diet and Food
Erectile Dysfunction
General Health
Glucagonoma
Guest Post
Hypertension
Insulin
Mental Health
News
Non-Insulin Injectable Medications
Pancreatitis
Research
Telehealth
Type 1 Diabetes
Type 2 Diabetes
Uncategorized
Weight Loss
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