Please note: a valid prescription is required for all prescription medication.
Plavix® is a prescription antiplatelet medicine that helps prevent harmful blood clots that can lead to a heart attack or stroke. From Canada, it ships to the US with US delivery from Canada and Canadian pricing. This page explains key facts and helps you order Plavix 75 mg online, even if you pay cash without insurance.
What Plavix® Is and How It Works
At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic. Plavix contains clopidogrel, a P2Y12 platelet inhibitor. It lowers the chance of clot formation by blocking ADP activation on platelets. This reduces platelet aggregation and helps keep blood flowing in narrowed or stented arteries.
Clopidogrel is a prodrug. The liver converts it to its active form, mainly through CYP2C19. People with lower CYP2C19 activity may have a reduced antiplatelet response. Your prescriber may consider this when choosing therapy. Plavix does not dissolve existing clots and does not relieve chest pain. It works silently in the background to reduce the risk of future events when taken every day as directed.
Who Plavix® Is For
Plavix is used to reduce the risk of heart attack and stroke in adults with atherosclerotic disease. This includes those with a recent heart attack, recent ischemic stroke, or established peripheral arterial disease. It is also used in acute coronary syndrome as part of dual antiplatelet therapy with aspirin, including after certain stent procedures.
People with active pathological bleeding should not take clopidogrel. This includes conditions like a current stomach ulcer or bleeding in the brain. Do not use if you have a known serious allergy to clopidogrel or other thienopyridines. Patients with Coronary Artery Disease often continue antiplatelet therapy long term as advised by their clinician.
Dosage and Usage
The typical maintenance dose is Plavix 75 mg once daily, with or without food. For acute coronary syndrome, a one-time loading dose is commonly used, followed by 75 mg daily. Many patients combine it with low-dose aspirin when clinically indicated. Dosing for ST-elevation or non-ST elevation events, and for patients of different ages, follows established labeling and cardiology guidance.
Only your prescriber can define the right schedule and duration. Follow the instructions on your prescription label. Do not stop or start antiplatelet therapy on your own, especially after a stent placement. If surgery or dental work is planned, your care team will give specific timing guidance to manage bleeding risk and stent protection.
Strengths and Forms
Plavix is supplied as film-coated oral tablets. Common strengths include:
- 75 mg tablet for daily maintenance
 - 300 mg tablet, often used as a loading dose when indicated
 
Availability can vary. Your dispensing pharmacy may stock one or more strengths. For a clinical overview of the 75 mg dose, see our editorial on Clopidogrel 75 Mg.
Missed Dose and Timing
If you miss a daily dose, take it when you remember the same day. If it is close to your next scheduled dose, skip the missed tablet and take the next dose at the regular time. Do not double up. Consistent daily dosing matters for protection. If you miss several doses, especially after a recent stent, contact your care team for guidance.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from moisture and heat. Keep Plavix in its original packaging until use. Do not store in a bathroom. Keep out of reach of children and pets.
When traveling, carry your medicine in your hand luggage, along with a copy of your prescription. Use a simple pill organizer for short trips, and keep the labeled package as backup. If you are crossing borders, bring documentation for your prescription. For longer trips, pack extra tablets in case plans change.
Benefits
Plavix helps reduce the risk of major cardiovascular events in appropriate patients, including heart attack and ischemic stroke. It supports stent protection as part of a dual antiplatelet plan when prescribed with aspirin. Benefits are preventive and increase with steady daily use. The 75 mg tablet is taken once daily and fits easily into most routines.
Many patients tolerate clopidogrel well. It can be taken with or without food. The medicine is widely studied, and clinicians use it across many cardiology settings where antiplatelet therapy is indicated.
Side Effects and Safety
- Bleeding, including nosebleeds and easy bruising
 - Gastrointestinal upset, stomach pain, diarrhea, or indigestion
 - Rash or itching
 - Headache or dizziness
 - Rare liver enzyme changes
 
Serious bleeding can occur, including gastrointestinal or intracranial bleeding. Thrombotic thrombocytopenic purpura (TTP), though rare, has been reported and requires urgent care. Severe allergic reactions can occur. Seek immediate medical help for signs like black stools, coughing up blood, sudden severe headache, unusual weakness, fainting, or swelling of the face or throat.
Patients with a history of bleeding disorders or recent major trauma require special caution. If you have a history of stroke, ulcer disease, or liver problems, your clinician will weigh risks and benefits. The effectiveness of clopidogrel may be reduced in certain CYP2C19 poor metabolizers.
Drug Interactions and Cautions
Combining Plavix with other medicines that affect clotting can increase bleeding risk. This includes anticoagulants such as Eliquis® or Xarelto®, heparins, and warfarin. Nonsteroidal anti-inflammatory drugs and many over-the-counter pain relievers can also raise bleeding risk.
Acid-reducing medicines that strongly inhibit CYP2C19, such as omeprazole and esomeprazole, may reduce clopidogrel activation in the body. Your prescriber may choose other gastric protection strategies if needed. Select antidepressants that affect platelets (for example, SSRIs and SNRIs) can add to bleeding risk. Always tell your care team about all prescription drugs, vitamins, and herbal products you use.
Avoid starting or stopping antiplatelet therapy without professional guidance. Before surgeries, dental procedures, or new prescriptions, your clinical team will coordinate safe timing to lower bleeding risk while maintaining protection.
What to Expect Over Time
Plavix starts inhibiting platelets soon after dosing, especially when a loading dose is used. Daily use maintains consistent antiplatelet effects. You will not feel the medicine working day to day. Its benefit is the reduced chance of a heart attack or stroke over time. Keep taking it as directed and attend follow-up appointments so your clinician can monitor benefit and safety.
Compare With Alternatives
Other P2Y12 inhibitors may be considered based on your clinical history, tolerance, and procedure details. Options include clopidogrel tablets, ticagrelor, and prasugrel. Your prescriber will decide which agent best fits your situation.
Some patients use Brilinta® as an alternative antiplatelet. Others may continue with Clopidogrel tablets when appropriate. For an overview of another option, see our editorial on Prasugrel 10 Mg. Therapy choices depend on risk factors, procedures, and your clinician’s advice.
Pricing and Access
Canadian pricing can help lower your Plavix 75 mg cost compared with typical US cash rates. You can check the Plavix 75 mg price, compare dosing options, and place an order online. From Canada, the medicine ships to the US with prompt, express shipping. US delivery from Canada keeps ordering simple and transparent.
Use this page to review strengths and add Plavix 75 mg to your cart. You can also review options to buy clopidogrel 75 mg if directed by your prescriber. Encrypted checkout protects your information. Looking for seasonal offers or added savings opportunities? Visit our Promotions page.
Availability and Substitutions
Specific strengths or package sizes may vary by inventory. If a strength is unavailable, your prescriber may recommend a clinically appropriate alternative or a temporary substitution. Pharmacists dispense according to your prescription and local regulations.
Patient Suitability and Cost Saving Tips
Plavix may suit adults with recent myocardial infarction, recent ischemic stroke, established peripheral arterial disease, or acute coronary syndrome when antiplatelet therapy is indicated. It is not for people with active pathological bleeding or a serious allergy to clopidogrel. Patients with high bleeding risk, liver disease, or planned procedures require individualized evaluation.
To manage costs, consider a multi-month supply if your prescriber anticipates steady dosing. This can reduce per-tablet pricing and lower shipping frequency. Set refill reminders so you do not run out unexpectedly. Store tablets correctly so every dose maintains quality. If therapy changes, contact customer care before reordering to update your prescription and avoid waste.
Questions to Ask Your Clinician
- Is Plavix 75 mg the right daily dose for my condition?
 - Do I need a loading dose before starting the maintenance tablet?
 - Should I take low-dose aspirin with clopidogrel, and for how long?
 - What signs of bleeding should I watch for, and when should I seek care?
 - Are omeprazole or esomeprazole appropriate for me, or should I use a different stomach medicine?
 - How will my other medicines affect bleeding risk or clopidogrel activity?
 - What is the plan for procedures or dental work while on antiplatelet therapy?
 
Authoritative Sources
DailyMed: Clopidogrel Labeling
Health Canada Drug Product Database
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What does Plavix 75 mg do?
Plavix 75 mg helps prevent platelets from clumping together. This lowers the risk of blood clots that can cause a heart attack or ischemic stroke when used as prescribed.
What is the usual Plavix 75 mg dose and schedule?
Most adults take one 75 mg tablet once daily. Some patients begin with a one-time loading dose for faster effect, then continue 75 mg daily. Your prescriber will set the plan.
Can I take Plavix with aspirin?
Yes, many patients take Plavix with low-dose aspirin when directed by their cardiology team, especially after certain heart events or stents. Only your clinician can advise duration.
Do I stop Plavix before surgery or dental work?
Do not stop on your own. Your clinician will weigh bleeding risk and stent protection and will advise if and when to pause and restart therapy for a procedure.
Are omeprazole or esomeprazole safe with Plavix?
These proton pump inhibitors can reduce clopidogrel activation through CYP2C19. Your prescriber may choose a different stomach medicine or adjust your plan as needed.
Can Plavix tablets be crushed or split?
Plavix is a film-coated tablet. Swallow whole unless your prescriber gives different instructions. If you have trouble swallowing, ask about safe alternatives.
Can I order Plavix 75 mg from Canada to the US?
Yes. We arrange US delivery from Canada with Canadian pricing. A valid prescription is required, and orders ship with prompt, express service.
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