Nesina® Tablets for Type 2 Diabetes

Nesina® (alogliptin) is an oral DPP-4 inhibitor used with diet and exercise to improve blood sugar in adults with type 2 diabetes. This page explains how it works, who it may suit, dosing, and safety, and helps you order from Canada with US delivery. We also outline options if you pay without insurance.

What Nesina® Is and How It Works

Nesina® is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases levels of incretin hormones that help the pancreas release insulin after meals and reduce glucagon. The result is better control of fasting and post-meal glucose. Orders ship from Canada to the US with secure handling.

Every CanadianInsulin order is prescription-checked with your clinic and dispensed by a licensed Canadian pharmacy.

Nesina is taken by mouth once daily and can be used alone or with other diabetes medicines. It is not insulin. It is not for type 1 diabetes or diabetic ketoacidosis. For a deeper overview of approved uses, dosing, and precautions, see our Nesina Uses guide.

Who Nesina® Is For

Nesina may be appropriate for adults with type 2 diabetes who need additional A1C reduction along with diet and exercise. It is an option if metformin alone is not enough, or when other agents are not tolerated. It can be added to metformin, thiazolidinediones, SGLT2 inhibitors, or basal insulin as directed by a clinician.

Nesina is not for people with type 1 diabetes or diabetic ketoacidosis. Use in pediatric patients has not been established. People with a history of pancreatitis, severe skin reactions, or serious allergic reactions to DPP-4 inhibitors should discuss risks with a clinician. Those with kidney problems may still use alogliptin, but dose adjustments apply.

To explore condition-focused support, visit our Type 2 Diabetes hub and our Blood Sugar Control category.

Dosage and Usage

The usual adult dose is 25 mg by mouth once daily. Take at the same time each day, with or without food. Swallow the tablet whole with water.

Kidney function guides dosing. Many labels recommend 12.5 mg once daily for moderate renal impairment and 6.25 mg once daily for severe renal impairment or end-stage renal disease. Your prescriber will base your dose on recent labs. If you use insulin or a sulfonylurea with Nesina, your clinician may adjust those drugs to reduce low blood sugar risk.

This is high-level dosing information. Always follow your prescriber’s instructions and the official prescribing information for alogliptin tablets.

Strengths and Forms

Nesina is supplied as film-coated tablets in several strengths:

• 6.25 mg tablets
• 12.5 mg tablets
• 25 mg tablets

Availability can vary by pack size and manufacturer. Patients who buy Nesina 25 mg tablets often use it as the standard strength. Those needing renal dose adjustments may use alogliptin 12.5 mg or alogliptin 6.25 mg.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember on the same day. If it is close to your next dose, skip the missed dose. Do not double up to make up for a missed tablet. Try to take Nesina at the same time each day to keep a steady routine.

Storage and Travel Basics

Store tablets at room temperature, typically 20 to 25°C (68 to 77°F). Keep the bottle closed tightly and protect from moisture. Do not store in a bathroom. Keep out of reach of children and pets.

When traveling, keep your medicine in carry-on luggage and in its original labeled container. Bring a copy of your prescription. If crossing time zones, aim for a once-daily schedule that fits your new local time.

Benefits

Nesina offers once-daily oral dosing with or without food. It is considered weight neutral for many patients. When used alone, DPP-4 inhibitors have a low risk of hypoglycemia. Alogliptin works on both fasting and post-meal glucose, which supports steady control across the day. It can be paired with metformin or other agents if additional lowering is needed. Because dosing can be adjusted for kidney function, it may be an option for patients with renal impairment.

Patients sometimes prefer to order Nesina tablets online because it simplifies refills and offers access to Canadian pricing with US shipping. These options can help those comparing the alogliptin tablets information and looking for clear instructions and safety details.

For comparisons within this class, see our editorial on Nesina vs Januvia.

Side Effects and Safety

Common side effects reported with alogliptin include:

• Upper respiratory tract infection or nasopharyngitis
• Headache
• Gastrointestinal discomfort, including nausea
• Back or joint pain
• Mild skin rash

Serious risks are uncommon but important. Pancreatitis has been reported; contact a clinician promptly for severe and persistent abdominal pain. Serious allergic reactions, including angioedema and severe skin reactions such as bullous pemphigoid, can occur. Some patients with cardiovascular disease have experienced worsening heart failure on certain DPP-4 inhibitors, including alogliptin; watch for rapid weight gain, swelling, or shortness of breath. Liver problems have been reported; seek care for unusual fatigue, dark urine, or yellowing of the skin or eyes. Hypoglycemia risk rises if Nesina is combined with insulin or sulfonylureas.

Call your clinician right away for symptoms that could indicate a serious reaction. Read the Medication Guide and the full Prescribing Information.

Drug Interactions and Cautions

Alogliptin has few significant drug interactions. Still, always share a full medication list, including over-the-counter medicines and supplements. Low blood sugar can occur when Nesina is combined with insulin or a sulfonylurea. Your clinician may adjust those other drugs. Use caution and discuss use if you have a history of pancreatitis, heart failure, or liver disease. Renal impairment requires dose adjustment.

To learn more about the class and expectations, see our overview of DPP-4 Inhibitors.

What to Expect Over Time

With consistent daily use, many patients see gradual improvements in fasting and post-meal glucose. Your A1C changes are usually assessed at your next lab check. The effect depends on your starting A1C, diet, activity level, and any additional diabetes medicines. DPP-4 inhibitors are often well tolerated over the long term. Keep scheduled follow-ups so your clinician can review logs, labs, and dose needs.

Compare With Alternatives

Other DPP-4 inhibitors include sitagliptin, marketed as Januvia®. It is also taken once daily and can be used alone or with other agents. For patients already on metformin who need alogliptin, the fixed-dose combination Kazano® (alogliptin with metformin) can reduce pill burden. Your clinician may also consider GLP-1 receptor agonists or SGLT2 inhibitors when appropriate. The choice depends on medical history, kidney function, A1C goals, hypoglycemia risk, weight goals, and tolerability.

Pricing and Access

Canadian pricing helps many patients compare the cost of alogliptin across strengths. You can view the current price of Nesina 25 mg from Canada, as well as 12.5 mg and 6.25 mg. You can then place your order with US delivery from Canada. Many patients search for buy Nesina 25 mg tablets, order Nesina tablets online, or buy alogliptin 25 mg tablets to compare options. We also support Alogliptin US shipping for those looking to manage monthly refills. Encrypted checkout is used to protect your information.

Check site pricing and add the strength your clinician prescribed. For seasonal offers, visit Promotions. Savings vary by strength and pack size.

Keywords people use when comparing options include Nesina Canadian pricing, Nesina dosage 25 mg, Nesina side effects, Alogliptin interactions, Nesina warnings, and Nesina uses. Use these as a checklist while you review this page and the label.

Availability and Substitutions

Availability may vary. If Nesina tablets are not available, your prescriber may recommend an alternative strength or a different DPP-4 inhibitor. Do not switch medicines without guidance from your clinician. We do not provide restock dates. Your clinician decides if a therapeutic substitution is appropriate.

Patient Suitability and Cost Saving Tips

Nesina may fit adults with type 2 diabetes who want once-daily dosing and a low hypoglycemia risk when used alone. It is not for type 1 diabetes or diabetic ketoacidosis. People with kidney disease may still use alogliptin with dose adjustments. Those with prior pancreatitis, serious skin reactions, or a history of heart failure should review risks in detail before starting.

Cost-saving ideas include ordering a multi-month supply when appropriate, which can lower the per-tablet cost. You can set calendar reminders for refills to avoid gaps. Keep your prescription current to prevent delays. If your prescriber changes your dose, update your order to match the new strength.

Questions to Ask Your Clinician

• Is Nesina the right add-on to my current diabetes plan?
• Which starting dose should I use based on my kidney function?
• How will we monitor for side effects, including pancreatitis or skin reactions?
• Could a combination tablet be better for me than separate pills?
• Do I need changes to insulin or sulfonylurea doses to reduce low blood sugar?
• What should I track at home to show how alogliptin is working?
• When should I schedule my next A1C and kidney tests?

Authoritative Sources

• DailyMed: Alogliptin
• Drugs@FDA: Search
• Health Canada: Drug Product Database

Place your order for Nesina tablets with US delivery from Canada.