Kazano® Tablets for Type 2 Diabetes

Kazano is a prescription tablet that treats type 2 diabetes. It combines alogliptin and metformin to help lower blood sugar. You can access Kazano without insurance with US shipping from Canada.

What Kazano Is and How It Works

Kazano® contains alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin, a biguanide. Together they help your body control glucose throughout the day. Alogliptin increases incretin activity, which boosts insulin release after meals and reduces glucagon. Metformin reduces glucose production in the liver and improves insulin sensitivity in muscles.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

This medicine is used with diet and exercise to improve glycemic control in adults with type 2 diabetes. It is not for type 1 diabetes or diabetic ketoacidosis. The combination can reduce pill burden compared with taking two separate tablets. For background on this DPP-4 class, see Nesina Tablets, which contain alogliptin alone.

If you want a broader overview of how medications fit together, review our guide to Diabetes Medications. For lifestyle context and diagnosis basics, you can browse the Type 2 Diabetes category.

Who It’s For

This treatment is indicated for adults with type 2 diabetes when diet and exercise alone are not enough. It may be used as initial therapy or as an add-on to existing regimens when appropriate.

Avoid use if you have severe renal impairment, known hypersensitivity to alogliptin or metformin, or metabolic acidosis, including diabetic ketoacidosis. It is not indicated for patients with type 1 diabetes. Your clinician may assess kidney function before starting and periodically afterward.

Dosage and Usage

Follow your prescriber’s instructions and the official label. Doses are individualized based on current therapy, effectiveness, and tolerability. Your clinician may start at lower strength and increase gradually to reduce gastrointestinal side effects.

Take tablets with food to help limit stomach upset. Swallow tablets whole with water. Do not crush or chew. Your prescriber may adjust dosing if you are switching from metformin or from a DPP-4 inhibitor. Do not exceed the maximum approved daily amounts for alogliptin and metformin, as listed in the label. If you are uncertain about your schedule or strength, consult the official prescribing information.

Kidney function is important when using metformin-containing products. Your clinician may check estimated glomerular filtration rate before starting and during treatment. Inform your healthcare provider about planned iodinated contrast imaging studies, significant alcohol use, or illnesses that may affect hydration or kidney function.

Strengths and Forms

Film-coated tablets are available in fixed-dose combinations. Availability may vary by pharmacy and region.

• Common presentations include alogliptin with metformin immediate-release tablets.
• Labeled strengths include alogliptin metformin 12.5/500 mg, 12.5/850 mg, and 12.5/1000 mg.
• Color, shape, and imprint may differ by strength.

For a look at other metformin products, see Extended-Release Metformin, which contains metformin in a different release profile.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to the next scheduled dose. If it is almost time for the next dose, skip the missed dose. Do not double up. Keeping a daily routine and using reminders can help maintain consistent dosing.

Storage and Travel Basics

Store tablets at room temperature in the original container. Keep them dry and away from heat, moisture, and direct light. Close the bottle tightly after each use. Keep out of reach of children and pets.

When traveling, pack your medication in your carry-on with a copy of your prescription. Use a pill organizer if helpful, and keep tablets in labeled containers for security screening. Plan extra supplies for delays and check local rules at your destination. For broader lifestyle planning with diabetes, you can read Diabetes Tips.

For condition-specific shopping, browse the Diabetes category or explore related Combination Tablets.

Benefits

This combination can simplify therapy by pairing two agents in one tablet. It targets fasting and post-meal glucose through complementary mechanisms. Using a single product may improve adherence for some patients.

Side Effects and Safety

• Stomach upset or diarrhea, especially at initiation
• Nausea or vomiting
• Gas or abdominal discomfort
• Headache
• Upper respiratory symptoms

Serious effects are uncommon but can occur. Lactic acidosis is a rare but serious risk with metformin, particularly with significant renal impairment or acute illness affecting kidney function. Pancreatitis has been reported with DPP-4 inhibitors. Severe allergic reactions, including rash or swelling, can occur. Hypoglycemia may occur when used with insulin or sulfonylureas. If you notice severe or persistent symptoms, contact a healthcare professional promptly.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements you use. Alcohol can increase the risk of lactic acidosis with metformin. Carbonic anhydrase inhibitors, certain diuretics, and corticosteroids may affect glycemic control or increase risks. Iodinated contrast procedures may require temporary interruption of metformin under medical supervision.

When used with insulin or secretagogues, your clinician may consider lowering those agents to reduce hypoglycemia risk. Review other agents for potential interactions that can raise or lower blood glucose.

What to Expect Over Time

Your clinician may use blood tests and glucose logs to assess response. Gastrointestinal effects often lessen after dose titration and with food. Consistent dosing, nutrition, and activity add to effectiveness. Keep follow-up appointments and share home readings to guide ongoing care.

Compare With Alternatives

Other fixed-dose combinations may fit certain needs. Janumet XR pairs sitagliptin with extended-release metformin in a once-daily form. Invokamet combines canagliflozin, an SGLT2 inhibitor, with metformin for a different mechanism. Single-agent options such as dapagliflozin or metformin ER may also be considered when appropriate.

Pricing and Access

Many patients compare options to understand the Kazano price and potential savings. Canadian pharmacy markets may offer lower list costs than typical US cash prices. You can review Kazano price in Canada and see how that compares for your situation.

Check product pages for current availability and options. Our encrypted checkout supports secure ordering. For periodic offers on diabetes therapies, see Promotions.

Availability and Substitutions

Supply can vary by strength and pack size. If your strength is unavailable, a prescriber may suggest a comparable alternative in the same class or a different class, based on your history and goals.

For cross-border fulfillment confidence, note that Kazano ships to US when dispensed from our licensed partners. If a substitution is recommended, your prescriber will decide the best option for you.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who need dual therapy and prefer a single-tablet option. It may not suit those with severe kidney disease, acute illness affecting hydration, or a history of hypersensitivity to its components. People with risk factors for lactic acidosis should discuss safety carefully with their clinician.

To reduce overall expenses, ask about multi-month quantities when appropriate, and use refill reminders to avoid lapses. Compare combination therapy with single-agent regimens to see what aligns with your clinical plan. Some patients also consider alternatives like Dapagliflozin if their prescriber advises a different mechanism.

Questions to Ask Your Clinician

• Is this combination appropriate with my kidney function?
• How should I time doses with meals?
• Which side effects should prompt a call?
• Do I need changes to insulin or sulfonylurea?
• Should I stop before contrast imaging?
• How often will labs be monitored?

Authoritative Sources

For official US labeling, see FDA DailyMed for Kazano; it provides approved indications and safety details. Access FDA DailyMed prescribing information. For manufacturer information, review the sponsor’s professional resources for alogliptin and metformin combinations. Visit Takeda’s professional site. For Canadian product monographs and approvals, Health Canada maintains the Drug Product Database. Search Health Canada DPD.

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Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.