Kazano® Tablets for Type 2 Diabetes

Kazano® is a prescription tablet that combines alogliptin and metformin. It is used with diet and exercise to help adults manage type 2 diabetes. Access is available with US delivery from Canada, and you can check Kazano cost without insurance before you place an order.

What Kazano Is and How It Works

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This medicine contains a DPP-4 inhibitor and a biguanide. Alogliptin limits the breakdown of incretin hormones, which can increase insulin release and lower glucagon after meals. Metformin reduces liver glucose output and improves insulin sensitivity in muscle and fat tissue.

You can Buy Kazano online through CanadianInsulin when you have a valid prescription. The combination targets different steps in glucose control. That dual approach may help lower A1C when used as directed.

To learn more about these classes, see Dpp 4 Inhibitors and Biguanides. An overview of class effects is also covered in our article DPP 4 Inhibitors Guide.

Who It’s For

The treatment is indicated for adults with type 2 diabetes, as an adjunct to diet and exercise. It is not for type 1 diabetes or for treating diabetic ketoacidosis. People with significant kidney disease must be evaluated before starting because metformin may not be appropriate in severe renal impairment. Those with a history of pancreatitis or heart failure should discuss risks with a healthcare professional.

Avoid use if you have metabolic acidosis, including diabetic ketoacidosis. Use caution with liver disease and with alcohol misuse, which can raise the risk of lactic acidosis. Safety and efficacy in pediatric patients have not been established.

Dosage and Usage

This combination is taken by mouth twice daily with meals. The regimen is usually chosen to match your current metformin dose, while targeting a total alogliptin amount of 25 mg each day. A common approach is to start at a lower metformin strength and increase gradually, as tolerated, to reduce stomach upset.

Swallow tablets whole with food. Do not split, crush, or chew. If you are transitioning from separate components, your prescriber may select the closest matching strengths. Kidney function should be assessed before initiation and periodically thereafter. Follow the official label and your prescriber’s directions for any adjustments.

When used alongside insulin or a sulfonylurea, the risk of low blood sugar can increase. Your prescriber may review your background therapy if you experience hypoglycemia symptoms.

Strengths and Forms

This medicine is supplied as immediate-release tablets in these strengths:

• 12.5 mg alogliptin with 500 mg metformin
• 12.5 mg alogliptin with 1000 mg metformin

Availability may vary by pharmacy and pack size. If you compare options, you may see references to Kazano tablets price when choosing a fill size. Ask your prescriber which strength aligns with your current plan.

Missed Dose and Timing

If you miss a dose, take it with food when you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. Keep doses spaced as prescribed to support stable glucose control.

Storage and Travel Basics

Store tablets at room temperature in the original, closed container. Protect from moisture and keep away from excessive heat. Keep out of reach of children and pets.

When you travel, carry your medicine in hand luggage with a copy of your prescription. Use a pill organizer only if it keeps tablets dry and labeled. For longer trips, bring extra doses and a medication list. At checkpoints, keep the bottle label visible to reduce delays. Do not store tablets in a hot car. If flying across time zones, maintain twice-daily spacing as best you can, and ask your prescriber for scheduling guidance when needed.

Benefits

This combination targets fasting and post-meal glucose through complementary mechanisms. It may help reduce A1C when used with diet and exercise. Taking a single co-formulated tablet can simplify regimens compared with separate components. The class generally has a low risk of hypoglycemia when used without insulin or a sulfonylurea.

Side Effects and Safety

• Stomach upset
• Nausea or vomiting
• Diarrhea
• Headache
• Upper respiratory symptoms

Serious but less common risks include lactic acidosis with metformin, pancreatitis, heart failure, severe allergic reactions, and liver injury. Stop the medicine and seek care for severe abdominal pain that does not resolve, shortness of breath, swelling of the legs, unusual fatigue, rash, or yellowing skin or eyes. The risk of low blood sugar can rise when used with insulin or a sulfonylurea.

Drug Interactions and Cautions

Tell your prescriber about all medicines you take. Carbonic anhydrase inhibitors, such as topiramate, can increase acidosis risk with metformin. Iodinated contrast imaging may require temporary interruption of metformin-containing products. Alcohol can increase the risk of lactic acidosis. Cimetidine and certain other cationic drugs may affect metformin clearance.

Using this therapy with insulin or a sulfonylurea may raise hypoglycemia risk. Your care team may monitor sugars more closely when combinations change.

What to Expect Over Time

Most people take this medicine long term as part of a broader plan. Digestive side effects often improve after dose titration and consistent use with meals. Your clinician may check A1C and kidney function at regular intervals. You may also be monitored for vitamin B12 levels during extended treatment.

Stable routines help adherence. Set reminders for morning and evening doses. Keep follow-up visits to reassess goals and tolerability.

Compare With Alternatives

If a single-agent option is appropriate, your prescriber may consider Nesina 28 Tablets (alogliptin alone). For a different dual-class option, SGLT2 combinations such as Invokamet may be considered in suitable adults. Other options in this area include dapagliflozin with metformin products and extended-release metformin formulations, depending on your history and goals.

Pricing and Access

Review current Kazano price comparisons alongside other therapies to plan your refill schedule. We list Alogliptin/Metformin price so you can compare this class with parallel options. For those looking at non-branded choices, you may also review Generic alogliptin metformin price and discuss suitability with your prescriber.

We provide Canadian pricing with transparent checkout and encrypted checkout safeguards. Fulfilment Ships from Canada to US for eligible orders with a valid prescription. If you are seeking coupons, see our Promotions page for current offers and terms.

Availability and Substitutions

Supply can vary by strength and pack size. If your preferred option is unavailable, a prescriber may recommend a therapeutically appropriate alternative in the same class or a different class. Do not switch products without medical guidance.

Patient Suitability and Cost-Saving Tips

Good candidates include adults with type 2 diabetes who need additional control beyond diet, exercise, or single-agent therapy. It may not be suitable for those with significant renal impairment, unstable heart failure, active liver disease, alcohol misuse, or a history of pancreatitis.

To manage expenses, consider multi-month refills when approved by your prescriber. Set refill reminders to avoid gaps in therapy. Compare Alogliptin Metformin tablets cost with category alternatives to find an option that fits your plan. Review coverage with your insurer, or use cash-pay pathways when appropriate. For background on the condition and related options, see Type 2 Diabetes, Oral Insulin Medications, and the product page for Dapagliflozin.

Questions to Ask Your Clinician

• Starting dose plan: how to titrate and when to reassess
• Kidney and liver checks: what labs and how often
• Hypoglycemia risk: signs to watch when used with other medicines
• GI effects: practical steps to improve tolerability
• Procedure planning: what to do before contrast imaging
• Travel refills: how many tablets to carry for extended trips

Authoritative Sources

• FDA DailyMed: Kazano
• FDA Prescribing Information: Kazano
• Health Canada Drug Product Database

Order Kazano online with US shipping from Canada, plus prompt, express, temperature-controlled handling when required. This page is for information only and does not replace professional medical advice.