Advair® HFA Inhaler for Asthma

Advair HFA is a metered-dose inhaler for long-term asthma control. It combines an inhaled corticosteroid with a long-acting bronchodilator to help reduce inflammation and improve airflow. You can order it with US shipping from Canada, which may help if you pay without insurance.

What Advair Is and How It Works

Advair® contains fluticasone propionate and salmeterol. It is a fixed-dose combination that pairs an anti-inflammatory corticosteroid with a long-acting beta2-agonist bronchodilator. As a Fluticasone salmeterol HFA inhaler, it works by reducing airway swelling and maintaining bronchodilation to help prevent asthma symptoms over time. This medicine is not a rescue treatment for sudden breathing problems.

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It improves day-to-day control when taken regularly as directed on the label. The treatment should be used alongside an asthma action plan set by your clinician.

Who It’s For

This product is indicated for the maintenance treatment of asthma in patients 12 years and older whose condition is not adequately controlled on inhaled corticosteroids alone. It should not be used to relieve acute bronchospasm or for status asthmaticus. Patients must have a separate rescue inhaler on hand.

People with known hypersensitivity to any component should avoid use. If you also manage Asthma under a clinician’s care, this combination can be part of your maintenance therapy. Use caution if you have cardiovascular disease, arrhythmias, seizure disorders, thyroid disease, diabetes, osteoporosis, glaucoma, or cataracts. This therapy is not approved for COPD in the HFA form; see the COPD category for appropriate options.

For immediate relief during a flare, use a fast-acting short-acting beta2-agonist as directed by your clinician, not this maintenance inhaler.

Dosage and Usage

Follow the Patient Information and your prescriber’s instructions. Typical schedules involve two inhalations by mouth twice daily, about 12 hours apart. Rinse your mouth with water and spit after each use to reduce the risk of oral thrush. Do not use a spacer device with this inhaler.

Before first use, prime the inhaler by shaking well and releasing test sprays into the air away from your face as described in the label. Re-prime if it has not been used for a period specified in the official instructions. Shake the inhaler before each dose. Exhale fully, place the mouthpiece in your mouth, seal your lips, start to inhale slowly and deeply, then press down on the canister. Continue to inhale, then hold your breath for up to 10 seconds, if comfortable. Wait briefly between inhalations as directed.

Do not exceed the prescribed number of inhalations. If symptoms persist, contact your clinician rather than increasing doses on your own. For clarity on patient instructions and titration, defer to the official label.

Ask your clinician about your Advair HFA dosage if switching from another inhaled therapy, and follow the prescribed plan.

Strengths and Forms

This HFA metered-dose inhaler is available in multiple strengths, each delivering two medications per actuation. Each canister includes a dose counter and comes with a protective cap.

• Fluticasone salmeterol 115/21 micrograms per actuation
• 45/21 micrograms per actuation
• 230/21 micrograms per actuation

Each inhaler typically provides 120 actuations per canister. Availability may vary by pharmacy and jurisdiction.

Missed Dose and Timing

If you miss a dose, take the next dose at your usual time. Do not double the next dose to make up for the missed one. Space doses about 12 hours apart when possible. This inhaler is not for sudden breathing problems; use a short-acting reliever for acute symptoms as instructed by your clinician.

Storage and Travel Basics

Store the pressurized canister at room temperature away from heat and open flame. Do not puncture or burn the canister, even when empty. Avoid freezing and prolonged exposure to temperatures above those stated on the label. Keep the cap on when not in use and clean the mouthpiece regularly according to the instructions.

When traveling, keep your inhaler and a copy of your prescription in your carry-on. Avoid leaving the canister in a hot car. If traveling internationally, keep medications in original labeled packaging. For broader product browsing and planning before trips, see the Respiratory category.

Benefits

This medicine combines two controller medications in one device. It may reduce day-to-day symptoms and help prevent exacerbations when taken consistently. The treatment can simplify regimens for patients who need both an inhaled corticosteroid and a long-acting bronchodilator.

Regular use may lessen reliance on short-acting rescue inhalers. It also provides a dose counter for tracking remaining actuations.

Side Effects and Safety

• Throat irritation or hoarseness
• Headache
• Upper respiratory tract infection
• Cough
• Oral candidiasis (thrush)
• Nausea
• Muscle or bone discomfort

Serious but less common risks include paradoxical bronchospasm, effects on heart rate or blood pressure, immunosuppression, adrenal effects, reduction in bone mineral density, ocular effects such as glaucoma or cataracts, and hypersensitivity reactions. LABA-containing combinations carry warnings; use only as directed and not for acute relief. Seek urgent care for severe breathing trouble or signs of an allergic reaction such as swelling or hives.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors (for example, ritonavir, cobicistat, ketoconazole) can increase fluticasone levels; avoid or monitor closely per label. Beta-blockers may reduce bronchodilator response. Use with other long-acting beta-agonists is not recommended. Diuretics can increase hypokalemia risk when combined with beta-agonists. Use caution with MAO inhibitors or tricyclic antidepressants due to potential cardiovascular effects.

Tell your clinician about eye disease, bone health concerns, infections such as tuberculosis, or exposure to chickenpox or measles. Discuss pregnancy or breastfeeding considerations. For broader respiratory options, review the COPD and Respiratory pages for education and product listings.

What to Expect Over Time

With regular use, you may notice more stable breathing control and fewer nighttime symptoms. Response varies, so continue your prescribed plan and keep a rescue inhaler accessible. Monitor the inhaler’s dose counter and plan refills in advance.

Track triggers and peak flow readings if recommended by your clinician. Review your action plan at follow-up visits. For general reading on emerging asthma research, see our article on ways to Reduce Asthma Attacks.

Compare With Alternatives

Other combination controllers are available. Budesonide with formoterol is one option that some patients use for maintenance treatment; see Symbicort® for details your clinician may consider. A dry-powder version of fluticasone with salmeterol is also available; compare device features with Advair Diskus® under clinician guidance.

Pricing and Access

Canadian pricing with home fulfillment can help make therapy more affordable. Check the current Advair HFA price and compare options. We provide transparent listings so you can review strengths and quantities before adding to your cart.

If you are looking for seasonal deals, visit our Promotions page for current offers. Ordering is straightforward, with encrypted checkout and support for prescription upload. US delivery details reflect cross-border fulfillment and Ships from Canada to US workflows.

Availability and Substitutions

Supply can vary by strength and quantity. If a strength is temporarily unavailable, your prescriber may recommend an alternative strength or a comparable class option. Generic Advair HFA is not widely marketed; your clinician may consider a different inhaled corticosteroid and LABA combination if needed.

Patient Suitability and Cost-Saving Tips

This therapy may suit adolescents and adults with persistent asthma requiring step-up control. It is not intended for children under 12 for this HFA presentation. Patients with significant cardiovascular disease, arrhythmias, or severe osteoporosis should review risks and benefits with a clinician.

To manage costs, consider multi-month supplies when appropriate, so you reduce order frequency. Set refill reminders based on your dose counter and daily schedule. Align follow-up appointments to reassess inhaler technique and adherence. For broader category browsing and options, consult the Respiratory section.

Questions to Ask Your Clinician

• Correct technique: How should I inhale and how long to hold?
• Controller plan: When to reassess dose or device type?
• Rescue therapy: Which reliever and when to use it?
• Side effects: How to reduce throat irritation or thrush?
• Interactions: Which medicines or supplements should I avoid?
• Monitoring: What goals should my action plan include?

Authoritative Sources

For full prescribing information, review the FDA label on DailyMed; see details for fluticasone propionate and salmeterol HFA at the FDA DailyMed database official site.

Manufacturer guidance is available; for device-specific instructions and safety information, visit the GSK product information pages.

For Canadian product data, consult Health Canada’s Drug Product Database entry for this combination at the Health Canada DPD search portal.

Ready to proceed? You can place your order with prompt, express shipping with temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.