Advair Diskus® Inhaler for Asthma and COPD

Advair Diskus® is a prescription inhaler that helps control asthma and COPD. It combines an inhaled corticosteroid with a long-acting bronchodilator for maintenance control. Review the Advair Diskus price without insurance along with availability, with US delivery from Canada.

What Advair Diskus Is and How It Works

This combination delivers fluticasone propionate to reduce airway inflammation and salmeterol to relax airway smooth muscle. Together, they help prevent symptoms such as wheeze, cough, and breathlessness. This therapy is not a rescue inhaler and will not relieve sudden breathing problems.

The Diskus device is breath actuated. A loaded dose releases when you inhale quickly and deeply through the mouthpiece. Rinse your mouth with water and spit after each use to lower the risk of oral thrush.

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Who It’s For

The treatment is indicated for long-term maintenance of asthma in patients who need both an inhaled corticosteroid and a long-acting beta2-agonist. It may be used in adults and in children 4 years and older for asthma maintenance.

For chronic obstructive pulmonary disease, it is indicated for maintenance treatment of airflow obstruction and to reduce exacerbations in appropriate adults. Use the Advair Diskus for asthma inhaler maintenance when a controller with both agents is suitable.

Do not use this device to treat sudden symptoms or for status asthmaticus. Avoid use if you have a severe allergy to milk proteins or to any component of the powder. People with significant cardiovascular disease, seizure disorders, thyroid disease, liver impairment, or infections should discuss risks with a prescriber.

Dosage and Usage

Follow the prescribing information and your prescriber’s directions. In asthma, the usual schedule is one inhalation twice daily about 12 hours apart. Your starting strength is based on prior controller therapy and symptom control. Do not exceed the recommended number of inhalations.

For COPD, the usual maintenance regimen is one inhalation of the Advair Diskus 250/50 inhaler twice daily. Continue using a short-acting bronchodilator for relief of sudden symptoms. Do not use this product for acute bronchospasm.

Using the device: open the Diskus, slide the lever until it clicks, then exhale away from the mouthpiece. Seal lips around the mouthpiece, inhale quickly and deeply, remove the device, and hold your breath briefly. Do not exhale into the inhaler. Close the device after use. Rinse your mouth and spit after each dose. Do not use a spacer with this dry powder device.

Always read the official label for full instructions. If technique is uncertain, ask your prescriber or a healthcare professional to review your inhalation steps.

Strengths and Forms

This medicine is supplied as a breath actuated dry powder Diskus with a built-in dose counter. Each unit contains 60 inhalations. Commonly published strengths include:

• 100/50 micrograms of fluticasone propionate and salmeterol per inhalation
• 250/50 micrograms of fluticasone propionate and salmeterol per inhalation
• 500/50 micrograms of fluticasone propionate and salmeterol per inhalation

Not all strengths are approved for every indication or available in every market. Availability may vary.

Missed Dose and Timing

If you miss a scheduled inhalation, take the next dose at your usual time. Do not take extra inhalations to make up for the missed dose. Try to use doses about 12 hours apart at consistent times each day.

Storage and Travel Basics

Keep the device dry and closed when not in use. Store at room temperature as directed on the label, away from heat, moisture, and direct sunlight. Do not wash or immerse the device. Discard the inhaler when the counter reads zero or when it reaches the labeled expiration date.

When traveling, carry your inhaler and prescription in your hand luggage. Keep it in a protective case to prevent accidental opening. Bring a copy of your prescription or a photo of the label for security screening. You can store your inhaler with your other medicines, but avoid humid bathrooms. Keep all medicines out of the reach of children.

Benefits

This treatment provides two mechanisms in one device, which can simplify maintenance therapy. The inhaled corticosteroid reduces airway inflammation. The long-acting bronchodilator helps keep airways open for extended periods. The Diskus format is breath actuated and includes a dose counter to help track remaining inhalations.

Side Effects and Safety

• Thrush in the mouth or throat
• Hoarseness or voice changes
• Throat irritation or cough
• Headache
• Tremor or nervousness
• Fast heartbeat or palpitations
• Muscle cramps
• Nausea
• Upper respiratory infection symptoms

Serious but less common risks can include pneumonia in patients with COPD, paradoxical bronchospasm, allergic reactions, adrenal effects with high exposures, reduced bone mineral density, and eye changes such as glaucoma or cataracts. Rinse your mouth and spit after each dose to help reduce the risk of thrush. Seek urgent care for severe breathing difficulty, hives, swelling, or chest pain.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors such as ritonavir, cobicistat, ketoconazole, itraconazole, or clarithromycin can increase systemic corticosteroid exposure. Monitor carefully if coadministration is unavoidable. Nonselective beta-blockers may blunt the effect of beta2-agonists. Diuretics that lower potassium can raise the risk of hypokalemia. Monoamine oxidase inhibitors and tricyclic antidepressants can potentiate cardiovascular effects of sympathomimetics.

Use caution if you have cardiovascular disease, arrhythmias, hypertension, convulsive disorders, hyperthyroidism, diabetes, osteoporosis, glaucoma, cataracts, active or latent infections including tuberculosis, or if you are immunosuppressed. Discuss pregnancy and breastfeeding considerations with a prescriber.

What to Expect Over Time

With regular twice-daily use and proper technique, symptom control may improve and rescue inhaler use may decline. Exacerbation risk may be reduced as control stabilizes. Relief is not immediate and the treatment works best when taken consistently. Keep using your rescue inhaler for sudden symptoms as directed by your prescriber. Schedule check-ins to review control, inhaler technique, and any side effects.

Compare With Alternatives

Other controller options combine an inhaled corticosteroid with a long-acting bronchodilator or add a muscarinic antagonist. Alternatives available here include Symbicort® and triple-therapy Trelegy Ellipta®, depending on diagnosis and prescriber guidance. Short-acting bronchodilators remain important for quick relief.

Learn more about conditions managed with these therapies in our resources on Asthma and COPD. For background on airway disease and metabolic health links, see Reduce Asthma Attacks and Respiratory Acidosis.

Pricing and Access

We display Canadian pricing with US delivery from Canada. You can compare out-of-pocket totals and see which strengths are available before you add to cart. If you use insurance, consult your plan about coverage.

For those paying cash, the Advair inhaler cash price can vary by strength and pack size. Actual totals may change as manufacturers update supply. Review the product page for current details. Check the Advair Diskus cost on the product page for current figures. Checkout is encrypted. Looking for a coupon? See our Promotions.

Availability and Substitutions

Supply can vary by strength and market demand. If a specific presentation is unavailable, a prescriber may recommend a clinically appropriate alternative. You can order Advair Diskus online when your prescription is verified and stock is available. We cannot provide restock dates.

Patient Suitability and Cost-Saving Tips

Candidates include people who need an inhaled corticosteroid plus a long-acting bronchodilator for asthma control, and adults with COPD who benefit from combination maintenance therapy. It may not be appropriate for patients with severe milk protein allergy or those who require only a short-acting reliever.

To help manage costs, consider multi-month fills if approved by your prescriber. A 60-dose device often aligns with a 30-day schedule at twice daily use. Set refill reminders so you do not run out. Keep a rescue inhaler available. Review technique at follow-up, as correct use supports symptom control and may prevent waste.

Questions to Ask Your Clinician

• Is this combination the right controller for my current asthma or COPD?
• Which strength should I start with, and when should we reassess control?
• Can you confirm my inhaler technique and breath speed for the Diskus?
• How should I adjust my action plan during infections or flare-ups?
• Which rescue inhaler should I carry, and how often may I use it?
• Do any of my medicines interact with this therapy, including antifungals or heart drugs?
• What signs of side effects should I report right away?

Authoritative Sources

• Manufacturer Site
• FDA DailyMed
• Health Canada DPD

When you are ready, place your request with prompt, express, temperature-controlled handling when required and US shipping from Canada. This content is educational and does not replace advice from your prescriber or the official label.