Browse Kidney Cancer

Kidney cancer, also known as renal cancer, is a disease where kidney cells become malignant and grow uncontrollably, forming a tumor. Most kidney cancers first appear in the lining of tiny tubes in the kidney. This type of kidney cancer is called renal cell carcinoma. Fortunately, most kidney cancers are found before they spread to distant organs. And cancers caught early are easier to treat successfully. However, these tumors can grow to be quite large before they are detected.

Causes of Kidney Cancer

The exact cause of kidney cancer is not known, but several risk factors have been identified. These include:

• Smoking: Smokers have a higher risk of developing kidney cancer compared to non-smokers. The risk decreases after quitting smoking.
• Obesity: Excess body weight is associated with an increased risk of kidney cancer.
• High Blood Pressure: Hypertension has been linked to a higher risk of kidney cancer.
• Family History: A family history of kidney cancer increases the risk of developing the disease.
• Genetic Conditions: Certain inherited conditions, such as von Hippel-Lindau disease, can increase the risk of kidney cancer.
• Exposure to Certain Substances: Workplace exposure to certain substances, such as cadmium and some herbicides, may increase the risk.

Symptoms of Kidney Cancer

In its early stages, kidney cancer often does not cause any noticeable symptoms. As the tumor grows, symptoms may include:

• Blood in the Urine: Hematuria is one of the most common symptoms of kidney cancer.
• Lower Back Pain: Persistent pain on one side of the lower back can be a symptom.
• Unexplained Weight Loss: Losing weight without trying can be a sign of kidney cancer.
• Fatigue: Feeling unusually tired or weak is a common symptom.
• Fever: Persistent fever not caused by an infection can be a symptom.
• Swelling: Swelling in the legs and ankles can occur.

Treatment of Kidney Cancer

Treatment for kidney cancer depends on the stage of the disease, the patient’s overall health, and personal preferences. Common treatments include:

• Surgery: The most common treatment for kidney cancer is surgery to remove the tumor. This may involve removing part of the kidney (partial nephrectomy) or the entire kidney (radical nephrectomy).
• Targeted Therapy: Drugs that target specific pathways involved in cancer cell growth are used to treat advanced kidney cancer. These include tyrosine kinase inhibitors and mTOR inhibitors.
• Immunotherapy: This treatment uses the body’s immune system to fight cancer. Drugs such as checkpoint inhibitors can help the immune system recognize and attack cancer cells.
• Radiation Therapy: Although not commonly used for kidney cancer, radiation therapy may be used to relieve symptoms or treat cancer that has spread to other parts of the body.
• Medications: We offer a range of medications for the treatment of kidney cancer. For more information, visit our Avastin page.

Prevention of Kidney Cancer

While there is no sure way to prevent kidney cancer, certain lifestyle changes can help reduce the risk:

• Quit Smoking: If you smoke, quitting can significantly reduce your risk of kidney cancer.
• Maintain a Healthy Weight: Staying at a healthy weight through diet and exercise can lower your risk.
• Control Blood Pressure: Keeping your blood pressure in check can help reduce your risk.
• Reduce Exposure to Harmful Substances: If you work with hazardous substances, follow safety guidelines to minimize exposure.
• Regular Check-ups: Regular medical check-ups can help detect kidney cancer early, when it is most treatable.

In conclusion, kidney cancer is a serious condition that requires prompt medical attention. Understanding the causes, symptoms, and treatment options can help manage the disease effectively. If you suspect any symptoms of kidney cancer, consult a healthcare professional for a proper diagnosis and treatment plan.