Beovu® Pre-filled Syringe for Wet AMD and DME

Beovu® is a brolucizumab intravitreal injection used to treat wet age-related macular degeneration and diabetic macular edema. This page covers the Beovu prefilled syringe without insurance options, dosing basics, and safety points. Ordering uses US shipping from Canada.

What Beovu Is and How It Works

This medicine is an anti-VEGF therapy. It binds vascular endothelial growth factor A to help reduce abnormal vessel leakage and retinal swelling. The treatment is given as a single intravitreal injection per visit by an eye specialist. In clinical use, it can decrease fluid and stabilize disease activity when used as directed on the official label.

Each brolucizumab prefilled syringe 6 mg is a sterile, single-use unit for intravitreal administration. Clinics follow aseptic technique, including eyelid and conjunctival disinfection, local anesthesia, and post-injection monitoring for intraocular pressure.

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Who It’s For

This treatment is indicated for adults with neovascular (wet) age-related macular degeneration and for diabetic macular edema. It should not be used in patients with active ocular or periocular infection, or in those with active intraocular inflammation. People with a history of serious hypersensitivity to brolucizumab or any component should avoid re-exposure. Use in pregnant or breastfeeding individuals requires clinician judgment, as human data are limited.

Learn more about these conditions under Age Related Macular Degeneration and Diabetic Macular Edema.

Dosage and Usage

Administration occurs in a retina clinic using intravitreal injection into the affected eye. Treatment often begins with more frequent visits, then the interval may be extended based on disease activity and the official label. An ophthalmologist evaluates vision, optical coherence tomography findings, and intraocular pressure before and after each injection. Patients are monitored for signs of intraocular inflammation and endophthalmitis following the procedure.

The care team prepares the eye with antiseptic and applies a local anesthetic. The needle enters the vitreous cavity at a recommended distance from the limbus using sterile technique. After injection, the needle is withdrawn slowly, and the site is assessed. Routine prophylactic topical antibiotics are not universally required per current practice standards; follow local protocols.

Strengths and Forms

The pre-filled syringe presentation is a single-dose unit intended for one eye. The labeled strength is 6 mg/0.05 mL. Availability and packaging may vary by dispensing pharmacy.

Missed Dose and Timing

If a scheduled injection is delayed or missed, the appointment should be rescheduled with the retina clinic. Do not attempt self-administration. The prescriber will determine when to resume and whether the interval needs adjustment based on clinical findings. Do not double up doses.

Storage and Travel Basics

Store the syringe refrigerated in the original carton and protect it from light. Do not freeze or shake. Typical label guidance specifies refrigerated storage between 2°C and 8°C. Keep out of reach of children. If transport is necessary, use an insulated container with cold packs and avoid temperature extremes. Carry documentation such as the prescription and a clinic letter when traveling. Keep the package with you in a carry-on bag, and avoid placing it in checked luggage or near dry ice.

Our partner pharmacies use temperature-controlled handling when required.

Pen Handling and Sharps Disposal

This is a pre-filled syringe administered by a trained eye-care professional. Do not reuse. After injection, the clinic disposes of the used syringe and needle in an approved sharps container according to local regulations.

Benefits

This anti-VEGF therapy targets VEGF-A, which can help reduce retinal fluid and leakage. The pre-filled syringe format removes drawing steps found with vials, which may streamline clinic workflow. Treatment intervals may be extended when disease is stable, as guided by the label and clinician assessment. Many patients value fewer preparation steps in busy clinic settings.

Side Effects and Safety

• Transient eye pain or discomfort after injection
• Conjunctival hemorrhage
• Blurred vision or floaters
• Increased intraocular pressure shortly after injection
• Inflammation inside the eye

Serious ocular events can occur, including endophthalmitis, retinal vasculitis, and retinal artery occlusion. New or worsening inflammation warrants immediate evaluation. Systemic arterial thromboembolic events are rare with intravitreal anti-VEGF therapy but remain a theoretical risk. Patients with a history of stroke or cardiovascular disease should be assessed carefully. Review the full prescribing information for complete safety details.

Drug Interactions and Cautions

Systemic drug interactions are unlikely due to minimal systemic exposure after intravitreal administration. However, caution is advised in people receiving anticoagulants or antiplatelet agents, as minor bleeding at the injection site may occur. Use is contraindicated in active ocular or periocular infection and active intraocular inflammation. The safety of use during pregnancy and lactation has not been established; decisions should balance potential benefits and risks.

What to Expect Over Time

After each injection, temporary floaters, mild irritation, or small subconjunctival hemorrhage may appear and usually resolve. Vision and fluid status are reassessed at follow-up visits with optical coherence tomography. Based on disease activity, the clinician may adjust the interval within the range described in the label. Adherence to scheduled visits is important to help maintain outcomes. For additional context on diabetic eye care, see Diabetic Eye Disease Month and a related explainer on anti-VEGF therapy alternatives in Uses Side Effects Dosage.

Compare With Alternatives

Other anti-VEGF options include aflibercept and ranibizumab. For reference, compare dosing schedules, clinic workflow, and safety information with Eylea® and the Product Lucentis Prefilled Syringe. Choice depends on disease characteristics, prior response, and clinician preference.

Pricing and Access

See current Beovu pre-filled syringe price and compare cash-pay options. Many patients look for brolucizumab injection prefilled syringe price transparency when budgeting for treatment. Orders are filled by licensed Canadian pharmacies with US delivery from Canada. You can view current pricing, request a quote, and upload a prescription through your account. For periodic offers, check our Promotions page.

Availability and Substitutions

Supply may vary by pharmacy and by lot. If this presentation is unavailable, a prescriber may recommend an alternative anti-VEGF product or a vial presentation when appropriate. We do not provide medical advice; treatment decisions remain with the prescribing clinician.

Patient Suitability and Cost-Saving Tips

Candidates typically include adults with a confirmed diagnosis of wet AMD or DME who can attend regular ophthalmology visits. Those with active ocular infection or intraocular inflammation should defer injection until resolved. If paying Beovu prefilled syringe out of pocket, consider planning multi-injection orders to reduce per-shipment costs. Set up refill reminders in your account to help coordinate clinic schedules. Ask the clinic if sample programs or foundation assistance are available for eligible patients.

To explore related options, browse our Age Related Macular Degeneration Amd category.

Questions to Ask Your Clinician

• Initial schedule: loading and maintenance plan
• Disease activity: how it is assessed
• Injection interval: when it can extend
• Safety signs: when to call promptly
• Same-day bilateral dosing: clinic policy
• IOP checks: before and after injection
• Post-injection care: drops and restrictions
• Travel plans: storage and timing
• Switch criteria: when to consider alternatives

Authoritative Sources

• Beovu HCP Information
• DailyMed: Drug Labeling
• Health Canada Drug Product Database

To proceed, order Beovu syringe online with US shipping from Canada and prompt, express, cold-chain shipping. This information is educational and not a substitute for professional medical advice.