Please note: a valid prescription is required for all prescription medication.
Beovu® is a prescription intravitreal treatment for wet age-related macular degeneration and diabetic macular edema. This page helps you review options for the Beovu prefilled syringe without insurance and arrange US delivery from Canada. Your retina specialist gives each dose in a clinical setting.
What Beovu Is and How It Works
Beovu contains brolucizumab, an anti-VEGF therapy that targets VEGF-A in the eye. By reducing abnormal blood vessel growth and leakage in the macula, this medicine helps control fluid and swelling that can harm central vision. CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.
The injection is supplied as a sterile, single-use device for intravitreal use only. Treatment is administered by a retina specialist under aseptic technique. After injection, the clinic typically checks intraocular pressure and perfusion of the optic nerve head. Follow the FDA-approved label and your prescriber’s instructions for every visit.
Who It’s For
This treatment is indicated for adults with neovascular, or wet, age-related macular degeneration and for diabetic macular edema. If you are being treated for Age Related Macular Degeneration or Diabetic Macular Edema, your retina specialist may consider this option based on imaging and disease activity.
It should not be used when there is an ocular or periocular infection or active intraocular inflammation. People with a history of retinal vasculitis or retinal vascular occlusion require careful assessment. Safety in pediatric patients has not been established. Discuss pregnancy and breastfeeding plans with your clinician before starting therapy.
Dosage and Usage
The injection is given into the vitreous cavity by a trained ophthalmic clinician. For wet AMD, therapy typically starts with three monthly doses, then continues at intervals based on disease control. For diabetic macular edema, therapy generally begins with monthly doses for a loading phase, followed by maintenance at intervals tailored by your prescriber. Each dose is 6 mg (0.05 mL), given as a single intravitreal injection per affected eye.
Do not attempt self-injection. Your clinic will prepare the eye using antiseptic and anesthetic measures. After treatment, follow post-injection care instructions and report symptoms such as severe eye pain, sudden vision changes, marked redness, or light sensitivity. If you have questions about scheduling or interval adjustments, ask your retina specialist to review the plan using the official label.
Strengths and Forms
The product is available in two presentations. Availability may vary by supplier.
- Beovu Pre-filled Syringe: ready for a single intravitreal dose; the syringe contains 6 mg/0.05 mL.
- Vial: single-use vial for clinic preparation; supplied for one dose.
Both presentations are designed for professional administration in a controlled setting. Your clinic will select the format that fits their workflow.
Missed Dose and Timing
If a visit is missed, contact your retina clinic to reschedule. The next appointment is typically booked as soon as practical to maintain disease control. Do not adjust timing on your own. Your clinician will review imaging and determine whether to continue, shorten, or extend the interval according to the label and your response.
Storage and Travel Basics
Clinics usually handle storage. If the medicine is delivered to you for transport to an appointment, keep it refrigerated in the original carton, protect it from light, and do not freeze. Use an insulated container with cold packs for travel. Avoid placing the carton directly against ice. Bring the shipment documentation to your visit so the clinic can log lot and expiry details.
For temperature-sensitive orders, CanadianInsulin arranges prompt, express, cold-chain shipping. If you plan air travel with the product, carry it on rather than placing it in checked baggage. Keep it out of reach of children and follow clinic instructions on transport and handoff.
Pen Handling and Sharps Disposal
The pre-filled syringe is for clinician use only. Your retina specialist prepares, administers, and disposes of the syringe following local regulations for sharps. Do not attempt to open, prime, or use the device at home.
Benefits
This anti-VEGF therapy is designed to control leakage and swelling in the macula. When disease activity is reduced, patients may experience stabilization of vision and improvement in retinal fluid on imaging. After the initial phase, some individuals can be maintained on extended intervals, which may reduce visit burden. The prefilled format supports efficient clinic workflow and consistent sterile technique.
Side Effects and Safety
- Eye pain or discomfort
- Conjunctival hemorrhage
- Transient increased eye pressure
- Blurred vision or floaters
- Foreign body sensation
- Cataract progression
Serious but less common risks include endophthalmitis, retinal detachment, intraocular inflammation, retinal vasculitis, and retinal vascular occlusion. Arterial thromboembolic events have been reported with intravitreal VEGF inhibitors. Seek urgent care for severe eye pain, sudden decrease in vision, pronounced redness, sensitivity to light, or new blind spots. Your clinician will discuss warning signs and provide instructions on when to call immediately.
Drug Interactions and Cautions
Clinically meaningful systemic drug interactions are unlikely with intravitreal brolucizumab. Nonetheless, inform your healthcare professional about all medicines, over-the-counter products, and supplements. Tell the clinic if you use antiplatelet or anticoagulant therapy, as minor ocular surface bleeding can occur with procedures.
Do not receive treatment in the presence of an active ocular or periocular infection or intraocular inflammation. Let your prescriber know about stroke history, uncontrolled glaucoma, or recent eye surgery. Use in pregnancy and lactation requires individualized risk-benefit discussion.
What to Expect Over Time
During the loading phase, clinic visits are more frequent to control leakage and assess response. If imaging shows stability, the interval may be extended according to the label and your prescriber’s judgment. Some patients require closer follow-up to maintain results. Staying on schedule and reporting symptoms promptly helps the care team manage vision risks safely.
Your clinician will use imaging such as OCT to monitor fluid and adjust the plan. It is common to see fluctuations in fluid early on. Consistent attendance and clear symptom reporting support steady decision-making over time.
Compare With Alternatives
Retina specialists may also consider other anti-VEGF agents based on your diagnosis and prior response. Options include Eylea® and the Lucentis® Prefilled Syringe. Dosing intervals, clinic workflow, and formulation details differ across agents. Your prescriber will select a therapy suited to your eye findings, medical history, and treatment goals.
Pricing and Access
Canadian pricing may lower cash-pay costs compared with typical US retail channels. For Beovu prefilled syringe US shipping, start a request once your prescription is confirmed. View current pricing and submit your order through our secure checkout. If you are looking for current offers, see Promotions for updates that may apply to eligible orders.
To estimate savings, compare your clinic’s buy-and-bill costs with our listed pricing. Your clinician can advise whether clinic-sourced or patient-supplied product is appropriate for your situation. We support encrypted checkout and careful handling for temperature-sensitive items.
Availability and Substitutions
Supply can vary by presentation. If the requested format is unavailable, your prescriber may recommend an alternative anti-VEGF agent or a different presentation. Your clinic will determine whether substitution is clinically appropriate.
Patient Suitability and Cost-Saving Tips
Good candidates are adults diagnosed with wet AMD or diabetic macular edema who can attend scheduled monitoring and injections. Patients with eye infections or active inflammation should defer treatment until cleared by a clinician. If you are unsure about candidacy, ask your retina specialist to review your imaging and medical history.
- Multi-visit planning: align follow-ups with work or caregiver schedules
- Supply timing: coordinate clinic availability before placing an order
- Refill reminders: set calendar alerts for upcoming visits
- Travel readiness: use insulated transport for clinic drop-off
- Education: review Wet Age Related Macular Degeneration basics and printed clinic materials
- Condition resources: see Eye Conditions for related topics
Questions to Ask Your Clinician
- Is anti-VEGF therapy appropriate for my eye findings right now?
- What monitoring schedule fits my disease activity and response?
- How do you assess when to extend, maintain, or shorten intervals?
- What warning symptoms should prompt an urgent call after an injection?
- Can I bring patient-supplied product to the clinic, and how should I transport it?
- How do my other health conditions affect safety considerations?
- If I do not respond as expected, what alternatives would you consider?
Authoritative Sources
Beovu Prescribing Information (Novartis)DailyMed: BrolucizumabHealth Canada Drug Product Database
Ready to proceed? Submit your prescription and place an order with Ships from Canada to US. All orders receive careful handling and tracked fulfillment. This information is not a substitute for professional medical advice; always follow your clinician’s directions and the official label.
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How is this injection different from other anti-VEGF treatments?
Brolucizumab targets VEGF-A to reduce abnormal vessel growth and leakage in the macula. It is given by intravitreal injection like other agents in the class, but dosing intervals and clinical decisions are individualized based on imaging and response. Your retina specialist will compare options in the anti-VEGF class, prior treatment history, and ocular findings when choosing the most suitable therapy for you.
What happens at the clinic on injection day?
A retina clinician prepares the eye with antiseptic and local anesthetic. The injection is delivered into the vitreous cavity under sterile technique. Afterward, your eye pressure and vision are checked. You receive instructions on symptoms that need prompt evaluation, such as severe pain, marked redness, light sensitivity, or sudden vision changes. Plan a ride if your eyes are dilated or if vision is temporarily blurry following the procedure.
How often are injections needed over time?
Frequency depends on the diagnosis and your response. Many patients start with a loading phase and then move to maintenance intervals based on disease activity and imaging. Some can be maintained on longer intervals, while others need closer follow-up. Your clinician will tailor the schedule according to the approved label and your individual results. Do not change visit timing without professional guidance.
Can I store the medicine at home before my appointment?
If the product ships to you, keep it refrigerated in the original carton and protect it from light. Do not freeze. Transport it to the clinic in an insulated container with cold packs and avoid placing it directly against ice. Bring shipment paperwork to your visit so the clinic can verify lot and expiry. If storage is a concern, ask the clinic whether they can receive and store the medicine on your behalf.
What side effects should I watch for after treatment?
Common effects include mild eye discomfort, small subconjunctival bleeding, floaters, or transient blurry vision. Serious symptoms that require urgent attention include severe eye pain, marked redness, sudden vision loss, light sensitivity, or new blind spots. These may signal conditions such as infection, retinal detachment, or significant intraocular inflammation. Follow your clinician’s instructions and contact the clinic immediately if concerning symptoms occur.
Is this treatment okay during pregnancy or breastfeeding?
Use during pregnancy or breastfeeding has not been fully established. Your prescriber will weigh potential benefits against risks based on your medical situation. If you are pregnant, planning to become pregnant, or nursing, discuss timing and alternatives before starting therapy. The decision is individualized and should follow the official label and your clinician’s judgment.
Can I switch to a different anti-VEGF agent if needed?
Switching may be considered if disease activity persists or if side effects limit continued use. Your retina specialist may review other agents in the class and adjust the plan based on imaging and prior response. Any change should follow clinical evaluation and the approved labeling for the chosen therapy. Do not stop or switch treatments without guidance from your healthcare professional.
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