What is Tradjenta?

Tradjenta, the brand name of Linagliptin, is an oral diabetes drug that is prescribed to patients with type 2 diabetes. This medication works by regulating the amount of insulin the pancreas produces after eating a meal. Linagliptin can be used alone or in combination with other type 2 diabetes medications to reduce high blood glucose levels in people with type 2 diabetes. The drug used together with exercise, diet, weight control and blood glucose testing. You should not change any of these factors in order to avoid affecting your blood glucose levels.

What is Januvia?

Januvia is the brand name of Sitagliptin, and is used to treat patients with type 2 diabetes. It can be used together with other diabetes drugs, but should not be used to treat type 1 diabetes. This medication is supposed to be taken orally, and can be taken with or without food. Your dosage will vary depending on how you respond to treatment, your medical condition, and kidney function. You should not take this medication if you are in a state of diabetic ketoacidosis or you are allergic to Sitagliptin.

Similarities and Differences Between Tradjenta and Januvia


Both Tradjenta and Januvia are oral medications that are used together with an exercise and diet program to control high blood glucose in patients with type 2 diabetes. The medications can be prescribed to patients with type 2 diabetes to help them control their blood glucose levels. Thus, reducing the risk of long-term health problems. However, these medications should not be used to treat patients who are under the age of 18.

Both drugs  belongs to a class of medications known as DPP-4 inhibitors. DPP-4 inhibitors are responsible for blocking the action of an enzyme called DPP-4 that destroys incretins, which reduces blood sugar levels. This helps to reduce high levels of blood glucose in the body. DPP-4 inhibitors such as Tradjenta and Januvia also work by reducing the amount of glucose that is produced by the liver when blood sugar levels rise. As well, both medications are less likely to cause hypoglycemia. You should not use these meds to treat patients with type 1 diabetes. When it comes to storage, the drugs should be stored under room temperature away from heat, moisture, and light.

Tradjenta Vs Januvia Differences

The recommended starting dose of Tradjenta is 5mg, which should be taken orally once every day. On the other hand, the average starting dose of Januvia is 100mg, and is also taken daily. You should not take these medicines in larger or smaller doses than what is recommended by your health-care provider. However, note that your doctor may require to change your dosage so that you can get maximum results out of these medications. As well, Tradjenta is a good option for those who have issues with their liver or kidney function. Tradjenta is also not associated to cause weight gain. Januvia, on the other hand, is not linked to worsening heart failure, unlike other medications in the same class. There is a small difference in cost, where Januvia is sold at a slightly higher price compared to Tradjenta.


Disclaimer: Please note that the contents of this community article are strictly for informational purposes and should not be considered as medical advice. This article, and other community articles, are not written or reviewed for medical validity by Canadian Insulin or its staff. All views and opinions expressed by the contributing authors are not endorsed by Canadian Insulin. Always consult a medical professional for medical advice, diagnosis, and treatment.