Invokamet® Tablets for Type 2 Diabetes

This combination tablet pairs canagliflozin with metformin for adults with type 2 diabetes. This page explains how it works, who it suits, and how to use it safely. You can review Invokamet® price without insurance and options with US delivery from Canada.

What Invokamet Is and How It Works

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

This medicine contains two agents that address high blood sugar in complementary ways. Canagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidney, which increases urinary glucose excretion and can lead to lower fasting and post‑meal glucose. Metformin is a biguanide that decreases hepatic glucose production and improves peripheral insulin sensitivity. Together, the treatment supports glycemic control as part of a broader plan that includes diet and activity.

Because this therapy combines two well‑studied mechanisms, clinicians may use it when metformin alone is not enough or when adding an SGLT2 inhibitor is appropriate. People often compare options and Canagliflozin metformin price when planning therapy changes. For broader context on related therapies, explore our Diabetes category.

Who It’s For

This tablet is indicated for adults with type 2 diabetes to improve glycemic control, when used with diet and exercise. It is not for type 1 diabetes or diabetic ketoacidosis. People with significant kidney problems, severe liver disease, or a history of lactic acidosis should not use metformin‑containing products. Those with volume depletion, recurrent genital infections, or high fracture risk may require closer monitoring when an SGLT2 inhibitor is part of therapy. Always confirm suitability with your healthcare professional.

For condition‑focused browsing, see our Type 2 Diabetes category.

Dosage and Usage

Follow your prescriber’s directions and the official label. The tablet is typically taken twice daily with meals to reduce stomach upset from the metformin component. Your prescriber will select a starting strength based on prior therapy and kidney function, then adjust gradually to balance tolerability and glycemic needs. Swallow tablets whole with water. Keep your daily schedule consistent and pair doses with meals you usually eat.

If you monitor blood glucose at home, record readings regularly and bring your log to visits. Report symptoms of dehydration, persistent urinary symptoms, or gastrointestinal intolerance. Before imaging procedures with iodinated contrast, let your clinician know you take a metformin‑containing product; temporary interruption may be needed per label. For additional background on this combination approach, see the article Invokana Metformin Combination.

Strengths and Forms

Film‑coated tablets are available in several strength pairs, commonly noted by canagliflozin/metformin content:

• 50 mg/500 mg
• 50 mg/1000 mg
• 150 mg/500 mg
• 150 mg/1000 mg

An extended‑release option (XR) also exists in similar pairings for once‑daily use; availability may vary by pharmacy and region. Selection depends on clinical factors, prior regimen, and tolerability. Patients sometimes review Canagliflozin metformin tablets price when comparing immediate‑release versus extended‑release formats. Your prescriber will decide which format suits your treatment plan.

Missed Dose and Timing

If you miss a dose, take it with food as soon as you remember the same day. If it is close to the next dose, skip the missed tablet and resume your regular schedule. Do not take two doses at once. Keeping doses with breakfast and dinner helps create a routine. If you miss doses frequently, discuss strategies with your healthcare professional to support adherence.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. When traveling, carry the medication in original labeled packaging, along with a copy of your prescription. A small pill organizer may help, but keep at least one labeled container for security checks and verification. Do not store tablets in a hot car. If you experience unusual odors, discoloration, or damage to tablets, consult a pharmacist before use.

Benefits

This dual therapy can simplify regimens by combining two agents in one tablet. It may reduce A1C more than either component alone in patients who need intensification. Taking doses with meals can improve metformin gastrointestinal tolerability for many people. The SGLT2 component may help reduce excess glucose without relying on insulin secretion, which can be useful for certain patients.

Side Effects and Safety

• Gastrointestinal upset: nausea, diarrhea, abdominal discomfort
• Increased urination and thirst
• Genital yeast infections and urinary tract infections
• Dizziness or low blood pressure, especially with diuretics
• Headache or fatigue

Serious risks are uncommon but important. Metformin can rarely cause lactic acidosis, particularly with severe kidney or liver disease, dehydration, or hypoxia. SGLT2 inhibitors can increase the risk of ketoacidosis, severe urinary infections, or rare necrotizing infections of the perineum. Bone fractures and volume depletion may occur, especially in susceptible individuals. Hypoglycemia can occur when used with insulin or sulfonylureas; monitoring and adjustments to those agents may be needed under clinician guidance. Seek urgent care for symptoms of severe infection, persistent vomiting, marked weakness, or trouble breathing.

Drug Interactions and Cautions

Tell your clinician and pharmacist about all medicines, supplements, and herbal products you use. Diuretics or RAAS blockers can increase risks related to volume depletion or potassium balance. Enzyme inducers such as rifampin may reduce canagliflozin exposure. Alcohol and carbonic anhydrase inhibitors can increase metformin‑related lactic acidosis risk. Iodinated contrast can affect kidney function and may require holding metformin temporarily. Consider the impact of other agents that lower glucose, as combined effects can raise the chance of hypoglycemia.

What to Expect Over Time

Glycemic improvements develop with consistent use, meal planning, and activity as advised by your care team. You may notice more frequent urination early on as glucose excretion increases. Gastrointestinal effects often improve as your body adjusts and as dosing is titrated carefully. Keep regular labs to assess kidney function and A1C, and discuss home glucose trends. For an overview of classes used in type 2 diabetes, see Common Diabetes Medications and the comparison article Invokana Vs Metformin.

Compare With Alternatives

Within SGLT2/metformin combinations, alternatives include dapagliflozin/metformin and empagliflozin/metformin. Options we carry include Xigduo® 60 Tablets and Synjardy®. Another common alternative outside the SGLT2 class is sitagliptin/metformin (often used when a DPP‑4 plus metformin is preferred). Your prescriber will match therapy to medical history, kidney function, and individual tolerability.

Pricing and Access

We list transparent options so you can compare formulations and strengths. If you track Invokamet price, review current availability and select the strength that fits your prescription. Orders ship through licensed Canadian pharmacies. US delivery is supported, and fulfillment Ships from Canada to US for eligible addresses. Checkout is encrypted, and support can clarify order steps before you proceed. For occasional offers, see Promotions.

Availability and Substitutions

Supply can vary by strength and format. If an item is temporarily unavailable, your prescriber may suggest an alternative SGLT2/metformin pairing or separate components. Patients sometimes compare Generic canagliflozin metformin price when a generic becomes available in their market; actual availability differs by region and time. Any substitution should be approved by your clinician to ensure comparable dosing and safety.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who need additional glycemic control beyond metformin and lifestyle measures. It may not suit those with severe renal impairment, recurrent severe infections, or risk factors for lactic acidosis. For budgeting, consider multi‑month refills, aligning medication refills with routine lab visits, and setting text or app reminders. Ask your prescriber whether tablet strengths can be adjusted to optimize both control and tolerability. If you plan to Buy canagliflozin metformin online, have your current prescription details ready and confirm the exact strength your clinician selected.

Questions to Ask Your Clinician

• Is this combination appropriate for my A1C target and kidney function?
• How should I time doses with meals and other medicines?
• What symptoms suggest I should pause the medicine and call you?
• How will we monitor for infections, dehydration, or lactic acidosis risk?
• Could alternatives in the same class or a different class fit me better?
• Do I need to adjust insulin or sulfonylurea doses when starting this therapy?

Authoritative Sources

Janssen Prescribing Information

FDA DailyMed: Invokamet

Health Canada Drug Product Database

Ready to proceed? Buy Invokamet online with prompt, express shipping and reliable US shipping from Canada. This page is informational and not a substitute for medical advice; always follow your prescriber and the official label.