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Janumet XR

Please note: a valid prescription is required for all prescription medication.

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Uses of Janumet XR

Janumet XR is a medication formulated as an extended-release tablet. It is a combination of two active ingredients: sitagliptin and metformin hydrochloride. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, while metformin is a biguanide. 

This combination medication is specifically designed to assist in the management of type 2 diabetes by improving glycemic control when used alongside proper diet and exercise. The extended-release formulation allows for once-daily dosing, enhancing convenience and compliance for patients.

Precautions and Warnings

If you have severe kidney problems, metabolic acidosis, or diabetic ketoacidosis, Janumet XR isn’t suitable for you. There’s a warning about lactic acidosis, which is a rare but serious side effect that you should be aware of.

Your doctor should regularly check your kidney function, blood counts, and Vitamin B12 levels while you’re taking Janumet XR. And if you’re pregnant or nursing, it’s crucial to discuss with your doctor before starting or continuing Janumet XR to ensure it’s safe for you and your baby.

Dosage

For adults, Janumet XR should be swallowed whole once per day with a meal, preferably in the evening. The dosage should be individualized.

Initial dosing depends on the patient’s previous treatment regimen. The maximum recommended daily dose is 100mg sitagliptin/2000mg metformin. 

Side Effects

Common side effects: 

  • Diarrhea
  • Upper respiratory infection
  • Headache
  • Nasopharyngitis
  • Hypoglycemia

Severe side effects:

  • Pancreatitis
  • Hypersensitivity reactions
  • Severe joint pain
  • Lactic acidosis 

More information about Jamunet XR

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Rewards Program

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