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Do I need a prescription to order Janumet XR?
Janumet XR is a prescription medicine, so we need a valid prescription from your healthcare provider before your order can be filled. You can upload it at checkout, or you or your doctor can email it to service@canadianinsulin.com or fax it to 1-866-951-0118. If the prescription is missing, your order won’t be processed until we receive it.
What does the price of Janumet XR include?
Prices on Canadian Insulin are in US dollars (USD), and the price in the buy box covers one pack of 60 tablets at the strength you select, multiplied by the number of packs you choose. Shipping is added at checkout and shown before you pay, and because Janumet XR ships dry-packed, you can choose Standard or Express shipping. Orders of $300 or less shipped from Canada carry a $35 surcharge.
Which Janumet XR strength and quantity should I order?
Janumet XR is listed in three strengths: 50 mg/500 mg, 50 mg/1000 mg and 100 mg/1000 mg, each in packs of 60 tablets. Choose the exact strength written on your prescription, then choose the number of packs that matches the tablet count your prescriber authorized. Strength and quantity are two separate choices, so check both before you add Janumet XR to your cart.
How is Janumet XR shipped and how long does it take?
Janumet XR tablets don’t need refrigeration, so they ship dry-packed. Orders usually ship within 48–72 hours of processing, or up to 5 business days in peak periods. After your order ships, Express delivery takes 3–5 business days and Standard delivery takes 5–10 days. Customs checks or weather can occasionally add time.
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Convert glucose readings between mg/dL and mmol/L without changing the clinical value.
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HbA1c & eAG Calculator
Convert between HbA1c percentage and estimated average glucose using the ADAG relationship.
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HOMA-IR Calculator
Estimate insulin resistance from fasting glucose and fasting insulin values collected from the same blood draw.
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Carb Serving Calculator
Convert total carbohydrate grams into carb choices for meal planning and diabetes education.
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CGM Time-in-Range Summary
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About Janumet XR
Janumet XR is an oral extended-release tablet that combines sitagliptin and metformin hydrochloride for adults with type 2 diabetes when used with diet and exercise. You can buy Janumet XR online and choose the labeled strength that matches your clinician’s directions, such as 50 mg/500 mg, 50 mg/1000 mg, or 100 mg/1000 mg. The product is not insulin, not metformin alone, and not labeled for type 1 diabetes or diabetic ketoacidosis.
Strength matching matters because each Janumet XR tablet contains two active ingredients in a fixed combination. Changing from one strength to another can change the amount of sitagliptin, metformin, or both. When ordering, use the exact tablet strength and quantity tied to your treatment plan rather than choosing only by tablet count or headline cost.
Janumet XR Price and What Your Total Covers
The Janumet XR price depends on three choices in the buy box: the strength, the number of 60-tablet packs, and the country of origin listed for that option. All prices are in US dollars (USD).
Shipping is added at checkout. Janumet XR can ship Standard or Express. Orders of $300 or less shipped from Canada carry a $35 surcharge. If your total is different from your last order, it’s usually because the strength, quantity or shipping method changed. See our shipping page for full rates and details.
How to Order Janumet XR Online
Before you order, have your prescription, your doctor’s contact details and a Visa or Mastercard ready.
- Sign in or create a free account.
- Choose your strength and the number of packs in the buy box, and add Janumet XR to your cart.
- Complete checkout and upload your prescription. You can also email it to service@canadianinsulin.com, or your doctor can email or fax it to 1-866-951-0118.
- You’ll receive a confirmation email once your order is placed.
Prefer to order by phone? Call 1-844-560-7790. See how to order for every ordering option.
Janumet XR Strengths and Pack Sizes Available
| Strength (sitagliptin/metformin) | Country of origin | Pack size |
| 50 mg/500 mg | Canada | 60 tablets |
| 50 mg/1000 mg | Canada | 60 tablets |
| 100 mg/1000 mg | Canada | 60 tablets |
All three are extended-release tablets that contain sitagliptin and metformin. The strengths aren’t interchangeable, so choose the one on your prescription.
How Janumet XR Is Taken
Janumet XR is taken by mouth once a day with a meal, following the schedule your prescriber sets. Don’t split, crush or chew the tablets. Your prescriber decides your strength and whether it changes, so don’t switch strengths unless they tell you to.
Store the tablets at room temperature in their original container, away from moisture, and out of reach of children.
What Janumet XR Is Approved For
Janumet XR combines sitagliptin, a DPP-4 inhibitor, with extended-release metformin, a biguanide. Alongside diet and exercise, it is approved to improve blood sugar control in adults with type 2 diabetes. It is not for type 1 diabetes, and it hasn’t been studied in people with a history of pancreatitis.
To learn more, read about the 3 P’s of diabetes, swollen feet and weeping legs in diabetes and Janumet dosage.
Janumet XR Safety Information
Janumet XR has a boxed warning about lactic acidosis, a rare but serious buildup of lactic acid in the blood caused by metformin. Get medical help right away if you have unusual muscle pain, trouble breathing, unusual sleepiness, stomach pain with nausea or vomiting, or feel very weak or cold.
Don’t take Janumet XR if you have severe kidney problems, metabolic acidosis or diabetic ketoacidosis, or if you’ve had a serious allergic reaction to sitagliptin or metformin. Tell your healthcare provider about kidney or liver problems, heart failure, heavy alcohol use and any upcoming surgery or X-ray with contrast dye.
The most common side effects are diarrhea, upper respiratory tract infection and headache. Serious side effects listed on the label include:
- inflammation of the pancreas (pancreatitis)
- heart failure
- kidney problems
- low vitamin B12 levels
- low blood sugar when taken with insulin or a sulfonylurea
- serious allergic reactions
- severe joint pain
- a skin condition called bullous pemphigoid
This isn’t a complete list. See the official prescribing information for full safety details.
How Janumet XR Compares to the Other Options in Its Class
Janumet XR belongs to the DPP-4 inhibitor class. Janumet contains the same sitagliptin with immediate-release metformin. Tradjenta contains linagliptin on its own, Jentadueto combines linagliptin with metformin, and Kazano combines alogliptin with metformin.
These medicines share a class, but each has its own approved uses, strengths and label, and they aren’t interchangeable. Your prescriber decides which one fits your treatment. Browse all DPP-4 inhibitors.
This content is for informational purposes only and is not a substitute for professional medical advice.
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Do I need a prescription for Janumet XR?
Yes. Janumet XR is a prescription medicine, and we need a valid prescription before your order can be filled. Upload it at checkout, or have your doctor email it to service@canadianinsulin.com or fax it to 1-866-951-0118. If you prefer, we can also contact your clinic to request the prescription.
Why does my Janumet XR total change between orders?
Your total depends on the strength, the number of packs, the country of origin and the shipping method you choose. All prices are in US dollars (USD). If any of these change, your total changes too. Orders of $300 or less shipped from Canada carry a $35 surcharge.
Is Janumet XR the same as the generic?
Janumet XR is Merck’s brand of sitagliptin with extended-release metformin, and this listing is brand-name Janumet XR from Canada. A generic would contain the same active ingredients, but whether you can switch is a decision for your prescriber or pharmacist.
How long does delivery take?
Orders usually ship within 48–72 hours of processing. After your order ships, Express delivery takes 3–5 business days and Standard delivery takes 5–10 days. We’ll email you a tracking number when it ships, and extra customs checks can sometimes add time. See our shipping page for full details.
Can I speak to someone before ordering?
Yes. Call us toll-free at 1-844-560-7790, email service@canadianinsulin.com, or start a live chat with our customer service team from our contact page. We’re available Monday to Friday 7am–11pm, Saturday 7am–7pm and Sunday 8am–5pm EST. Outside those hours, send us a message or an email and our team will pick it up when we open.
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