Onsior Dog product overview for canine pain and inflammation

Onsior Dog is a veterinary prescription nonsteroidal anti-inflammatory drug used in dogs to help reduce pain and inflammation. It contains robenacoxib, a COX-2–preferential NSAID (a type of anti-inflammatory pain reliever). This page summarizes typical uses, dosage basics, key safety risks, and handling points to review with a veterinarian.

Information here is general and does not replace the product label or your dog’s individualized treatment plan.

What Onsior Dog Is and How It Works

Robenacoxib works by inhibiting cyclooxygenase enzymes involved in prostaglandin production. Prostaglandins are chemical messengers that contribute to inflammation, pain signaling, and fever. In dogs, robenacoxib is often described as COX-2–preferential, meaning it targets the inflammatory pathway more than COX-1, which supports normal stomach lining, kidney blood flow, and platelet function. Even with COX-2 preference, clinically important stomach or kidney effects can still occur, especially in higher-risk animals.

Some patients explore US delivery from Canada when their veterinarian provides a valid prescription and local rules allow. When needed, prescription details are confirmed with the prescribing veterinarian. In practice, this medicine is used to support comfort and mobility by lowering inflammation that drives soreness, stiffness, and post-procedure pain, while aiming to keep normal protective functions as intact as possible.

Who It’s For

This medicine is used in dogs when a veterinarian determines an NSAID is appropriate for controlling pain and inflammation. Common clinical contexts include osteoarthritis-related discomfort and certain short-term pain situations, such as after a procedure, depending on the approved labeling in your jurisdiction. If you are browsing condition hubs for context, see the CanadianInsulin site listings for Canine Osteoarthritis and Canine Pain.

Onsior Dog is not appropriate for every dog. Veterinarians are typically cautious in pets with a history of gastrointestinal ulceration or bleeding, significant kidney or liver disease, dehydration, or those taking other drugs that raise bleeding or kidney risk. It may also be avoided in dogs with known hypersensitivity to NSAIDs. Puppies, seniors, and dogs with multiple chronic conditions may require closer monitoring, because adverse effects can be harder to detect early.

Dosage and Usage

For most dogs, dosing is weight-based and given once daily, but the exact mg/kg schedule and duration should follow the label and your veterinarian’s directions. Onsior Dog dosage instructions often differ by indication (for example, short-term postoperative pain versus chronic osteoarthritis discomfort), and the planned course length matters for safety monitoring. Do not increase the dose, add extra doses, or extend use beyond what the prescriber recommends.

Administration details can affect both tolerability and effectiveness. Some NSAIDs are directed to be given with food, while others are directed to be given on an empty stomach; follow the specific robenacoxib product label you received. If vomiting, poor appetite, diarrhea, dark stools, unusual thirst, or decreased urination occur, contact a veterinary clinic promptly, because these signs can indicate gastrointestinal irritation or kidney stress. If you manage multiple medicines at home, the general primer Common Diabetes Medications can help with the idea of drug classes and why mixing therapies needs review.

Why it matters: Many serious NSAID problems start as mild stomach or behavior changes.

Strengths and Forms

This product is supplied as oral tablets for dogs, with the goal of allowing accurate weight-based dosing. Common presentations include Onsior 10 mg for dogs, Onsior 20 mg tablets for dogs, and Onsior 40 mg tablets for dogs; availability can vary by country and pharmacy supply. Tablets are typically packaged to help protect them from moisture and to support correct day-to-day use.

Veterinary teams may choose a particular tablet strength based on the dog’s current body weight, the target dose range on the label, and whether splitting tablets is allowed for that specific product. If you receive more than one strength, keep each package clearly separated and review the label each time you give a dose. For browsing other animal health items carried on the site, the Pet Medications hub can help you compare categories without assuming any one product is right for your dog.

Storage and Travel Basics

Store robenacoxib tablets at room temperature, away from excess heat and humidity, and keep them in the original packaging until use. This helps protect the tablets from moisture and reduces mix-ups with other medications. Keep all pet medicines out of reach of children and animals, because accidental ingestion can cause serious adverse effects. If a blister pack is damaged or a tablet is crumbling, ask a pharmacist or veterinary clinic about safe replacement and disposal.

When traveling, pack the medication in its labeled packaging and bring the prescription information if possible. Plan for consistent daily timing, but avoid making dose changes without veterinary guidance if a dose is missed. If your household also uses injectable medicines, the overview Insulin Pen Vs Syringe reviews general organization and handling habits that can reduce mix-ups. For broader trip-planning ideas (such as keeping medicines accessible and avoiding hot cars), the site resource How To Travel includes practical packing concepts that can be adapted for many prescriptions.

Quick tip: Keep a simple medication log with date and time.

Side Effects and Safety

Like other NSAIDs, robenacoxib can cause side effects related to the stomach and intestines, kidneys, liver, or bleeding risk. Mild effects may include decreased appetite, vomiting, diarrhea, soft stools, or lower energy. These can be early warning signs that your dog is not tolerating the medicine well. Onsior Dog should be stopped only under veterinary direction, but new or worsening symptoms should be reported quickly so a clinician can advise next steps.

More serious risks include gastrointestinal ulceration or bleeding (which may show as black/tarry stool, blood in vomit, pale gums, or weakness), acute kidney injury (increased thirst, reduced urination, dehydration), and liver injury (jaundice, marked lethargy). Hypersensitivity reactions are uncommon but can be urgent. Many veterinarians recommend baseline and follow-up lab work for dogs on longer courses, especially seniors or pets with other medical problems. If you want a general framework for recognizing and documenting side effects, the article Common Toujeo Side Effects illustrates symptom-tracking habits that can also help when reporting veterinary concerns.

Drug Interactions and Cautions

NSAID interactions are a major safety issue in dogs. Avoid combining robenacoxib with other NSAIDs (such as carprofen, meloxicam, deracoxib, or firocoxib) unless a veterinarian specifically prescribes a transition plan, because stacking similar drugs can increase ulcer and kidney risk. Corticosteroids (for example, prednisone) can also raise the chance of gastrointestinal bleeding when used with NSAIDs. Tell the veterinarian about any over-the-counter products, supplements, or topical agents your dog receives.

Caution is also common when a dog is taking medicines that affect kidney blood flow or fluid balance, such as diuretics, ACE inhibitors, or certain blood pressure drugs, as well as anticoagulants or antiplatelet drugs that can influence bleeding. Dehydration, vomiting/diarrhea, and heat stress can increase kidney vulnerability during NSAID therapy. For a general patient-safety mindset around medication risks and red flags, see Ozempic Danger Safety Guide for an example of how safety checklists are structured, while noting it is written for human medicines.

Compare With Alternatives

Veterinarians often choose among several canine NSAIDs based on the dog’s history, prior response, and the specific indication on the label. Common alternatives in practice include carprofen, meloxicam, deracoxib, and firocoxib. These drugs share similar benefits and risk categories (particularly gastrointestinal and kidney risks), but they differ in dosing schedules, formulations, and individual tolerability. If a dog has had an adverse reaction to one NSAID, a veterinarian may choose a different option or pursue a different pain-control approach.

Onsior Dog may also be considered alongside non-NSAID strategies, depending on the cause of pain. Adjunct options can include disease-modifying osteoarthritis plans, weight management, controlled exercise, physical rehabilitation, and selected analgesics such as gabapentin in specific cases. Supplements (for example, omega-3 fatty acids) are sometimes discussed for long-term joint support, but they should not be viewed as a substitute for veterinary evaluation when pain is significant or worsening.

Pricing and Access

A valid veterinary prescription is typically required. Coverage and reimbursement, including pet insurance benefits, vary widely by plan and may depend on diagnosis, prior authorization rules, and whether the medicine is considered chronic or short-term. Some people compare cash-pay options, and costs may differ by tablet strength, package size, and the planned duration of therapy. If a household is managing medications without insurance, it can help to ask the veterinary clinic what monitoring or recheck visits are expected during longer NSAID courses.

On CanadianInsulin, dispensing is completed by licensed third-party pharmacies where regulations permit. Documentation needs can include the original prescription, prescriber contact details, and confirmation of the dog’s current weight for correct dosing. Refill limits, substitution rules, and brand versus generic availability can also vary by jurisdiction. For non-time-specific site information, the Promotions Page may list general offers, but it should not replace clinical decision-making or prescription requirements.

Authoritative Sources

For U.S. regulatory labeling context, consult FDA Animal Drugs at FDA database.

For veterinary NSAID safety background, see Merck Veterinary Manual NSAID overview.

Depending on medication needs and destination, partner pharmacies may use prompt, express, cold-chain shipping when appropriate.

This content is for informational purposes only and is not a substitute for professional medical advice.