Onsior® for Dogs (Robenacoxib) Tablets for Pain Relief

What Onsior® Is and How It Works

Onsior® (robenacoxib) is a nonsteroidal anti-inflammatory drug (NSAID) for dogs. It helps control pain and inflammation associated with osteoarthritis and soft tissue surgery. Many pet owners search for Onsior Dog tablet strengths such as 5 mg, 10 mg, 20 mg, and 40 mg to match veterinary dosing plans.

CanadianInsulin is a prescription referral service. Prescriptions are verified with your clinic, and orders are filled by licensed Canadian pharmacies.

We work with licensed, vetted partner pharmacies to source authentic brand medications across a broad selection, with value-focused pricing.

Robenacoxib is a COX-2 selective NSAID. It targets enzymes involved in inflammatory pain while sparing COX-1 activity that supports normal stomach and kidney function. In dogs, robenacoxib acts quickly in inflamed tissues, which supports fast pain relief. Tablets are given by mouth, typically once daily, as directed by the veterinarian.

Onsior tablets for dogs are available in multiple strengths to accommodate different body weights. The aim is to deliver an effective dose while minimizing gastrointestinal and renal side effects seen with NSAIDs when misused or combined with other anti-inflammatory drugs.

Dosage and Usage

• Typical dosing for osteoarthritis: 1 mg/kg once daily (up to 2 mg/kg) as directed by the veterinarian.
• Postoperative use is often once daily for up to 3 days, per the surgical plan.
• Available strengths: 5 mg, 10 mg, 20 mg, and 40 mg tablets for dogs. The veterinarian selects the combination that fits the dog’s weight.
• Give at the same time each day. Follow the clinic’s advice on giving with or without food.
• Do not use with other NSAIDs or corticosteroids unless the veterinarian instructs and an appropriate washout period is observed.
• Missed dose: give when remembered unless it is near the next scheduled time. Do not double dose.
• Administration steps: confirm the prescribed strength(s); remove a tablet from the blister; offer directly or with a small treat; ensure the full dose is swallowed; wash hands after handling.
• Do not split or crush tablets unless specifically instructed by the veterinarian.

• Storage: keep tablets at 20–25°C (68–77°F); brief excursions 15–30°C (59–86°F) are acceptable.
• Protect from moisture and light. Keep tablets in the original blister until use.
• Keep out of reach of children and other pets.
• Travel: pack medication in carry-on luggage with original label. Avoid leaving tablets in cars or hot environments above 30°C (86°F).
• Use a small, protective pill case for short trips and keep a copy of the prescription.

Benefits and Savings

Onsior provides targeted relief for canine osteoarthritis pain and inflammation. Robenacoxib’s COX-2 selectivity supports joint comfort while aiming to limit stomach and kidney impact compared with nonselective NSAIDs. Once-daily dosing is convenient, and flavored tablets can help with acceptance in many dogs.

Many customers save 60–80% vs typical U.S. prices when ordering through CanadianInsulin.

Authentic Elanco Onsior for dogs comes from licensed Canadian pharmacies, offering consistent quality and dependable availability alongside value-focused pricing.

Side Effects and Safety

• Common effects: vomiting, soft stool or diarrhea, decreased appetite, lethargy, or increased thirst.
• Less common: elevated liver enzymes, constipation, oral irritation, or behavior changes.
• Stop therapy and contact the veterinarian if repeated vomiting, black/tarry stool, bloody stool, jaundice, or marked tiredness occurs.
• Do not use in dogs with known NSAID sensitivity, active gastrointestinal ulceration or bleeding, severe kidney or liver disease, or bleeding disorders.
• Avoid use with other NSAIDs (including aspirin) or corticosteroids unless directed with a washout period.

Serious risks with NSAIDs can include gastrointestinal ulceration or perforation, kidney injury, and rare severe liver reactions. Use cautiously in dehydrated, hypovolemic, or hypotensive patients. Safety in breeding, pregnant, or nursing dogs may not be established. Regular veterinary monitoring is advised for long-term therapy.

Onset Time

Initial pain relief may begin within hours of the first dose as robenacoxib reaches inflamed tissues. Noticeable improvements in mobility for osteoarthritis often appear within several days, with fuller benefits developing over 1 to 2 weeks as steady daily dosing continues. Postoperative comfort support is typically seen throughout the 3-day treatment window when used for soft tissue surgery pain.

Compare With Alternatives

Several veterinary NSAIDs and pain therapies are used for canine osteoarthritis. Carprofen (e.g., Rimadyl) is a long-standing option with twice-daily or once-daily dosing depending on the regimen. Firocoxib (Previcox) is another COX-2 selective NSAID given once daily. Deracoxib (Deramaxx) offers once-daily dosing, particularly in postoperative settings.

Grapiprant (Galliprant) is a non-COX NSAID that blocks the EP4 receptor for prostaglandin E2, which may be useful in some dogs who require an alternative approach. Choice among these depends on the dog’s medical history, concurrent medications, prior NSAID tolerance, and the veterinarian’s assessment. Onsior’s pharmacology features include COX-2 selectivity and rapid distribution to inflamed tissues, which can support quick pain relief.

Combination Therapy

• Adjunct analgesics: gabapentin or tramadol may be used alongside an NSAID for multimodal pain control when prescribed.
• Joint care: omega-3 enriched diets, weight management, physical therapy, and approved joint supplements (e.g., glucosamine/chondroitin) can complement NSAID therapy.
• Gastroprotection: some dogs may receive stomach protectants (e.g., omeprazole or sucralfate) if they are at higher gastrointestinal risk.
• Avoid duplicate anti-inflammatories: do not combine Onsior with another NSAID or a corticosteroid unless the veterinarian directs and manages a washout.

Patient Suitability and Cost-Saving Tips

Candidates include dogs with osteoarthritis or those needing short-term relief after soft tissue procedures, when an NSAID is appropriate and no contraindications exist. Dogs with a history of NSAID intolerance, gastrointestinal ulcers, severe kidney or liver disease, bleeding disorders, or dehydration may not be suitable. Use caution in very young, underweight, pregnant, or nursing dogs, and in dogs on diuretics or nephrotoxic drugs.

To manage costs, consider ordering a multi-month supply once the maintenance dose is stable. Add other pet prescriptions to the same order when appropriate to simplify logistics. Set simple reminders for reordering in advance of running out. CanadianInsulin provides prompt, express, cold-chain shipping for reliable delivery.

Authoritative Sources

Elanco product information for Onsior (robenacoxib)

Health Canada Drug Product Database: robenacoxib listings

European Medicines Agency EPAR: Onsior (robenacoxib)

Order Onsior® from CanadianInsulin: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is for educational purposes and does not replace professional veterinary advice. Always follow your veterinarian’s instructions and the approved product labeling.