Onsior® Solution for Cats: Injectable NSAID for Post‑Op Pain Control

What Onsior® Is and How It Works

Onsior Solution is the injectable form of robenacoxib, a selective COX‑2 nonsteroidal anti‑inflammatory drug (NSAID) for cats. It is used to manage post‑operative pain and inflammation associated with soft‑tissue surgery. Onsior Solution without insurance may be more affordable through a licensed referral service. CanadianInsulin is a prescription referral service. Prescriptions are verified with your clinic, and orders are filled by licensed Canadian pharmacies. Partner pharmacies are licensed and vetted, medications are authentic brand products, and pricing is value‑focused with a broad selection.

The solution is given as a subcutaneous injection, often before surgery and then once daily for up to several days as directed by a veterinarian. Robenacoxib works by preferentially blocking COX‑2 enzymes that drive inflammatory prostaglandins, while sparing COX‑1 activity that supports the stomach, kidneys, and platelets. This COX‑2 selectivity helps reduce pain and swelling with a safety profile designed for short‑term use in cats.

Robenacoxib distributes rapidly to inflamed tissues and maintains therapeutic levels there while clearing from blood relatively quickly. This pharmacologic profile supports targeted relief of acute surgical pain with once‑daily dosing over a brief recovery period.

Dosage and Usage

• Administration: Subcutaneous injection for cats, provided by a veterinarian or only under veterinary direction.
• Timing: Commonly given shortly before surgery, then once daily during the immediate post‑operative period as prescribed.
• Duration: Short course use over a few days is typical; do not exceed the prescribed duration.
• Missed dose: If a scheduled dose is missed, do not double the next dose. Contact the veterinarian for guidance on resuming.
• Injection sites: Administer under the skin, such as over the shoulder area. Rotate injection sites to reduce local irritation.
• Technique (if instructed for at‑home use): Inspect the vial for clarity and expiry date; disinfect the stopper; use a sterile syringe and needle; draw the prescribed volume; pinch skin to create a tent; insert needle subcutaneously; inject slowly; dispose of sharps safely.
• Do not use concurrently with other NSAIDs or corticosteroids. Allow adequate washout if switching therapies per veterinary guidance.
• Provide water access and monitor appetite, behavior, and stool during recovery. Report concerning changes to the veterinarian.

• Storage: Keep vials at controlled room temperature, 20–25°C (68–77°F). Short excursions 15–30°C (59–86°F) are generally acceptable. Do not freeze. Protect from light.
• In‑use handling: Follow the labeled in‑use shelf life after first puncture. Do not use if the solution is discolored, cloudy, or contains particles.
• Travel: Keep the vial upright in a padded, leak‑proof case. Avoid heat, direct sun, and car dashboards.
• Long trips: Use an insulated pouch if temperatures may exceed 30°C (86°F). Do not allow the medication to freeze.
• Home safety: Store out of reach of children and pets. Keep with original labeling and prescription details.

Benefits and Savings

Onsior Solution provides targeted COX‑2 inhibition for cats during surgical recovery. It reduces inflammatory pain and swelling, helps cats return to normal eating and grooming sooner, and is designed for short, once‑daily courses. The injectable form offers consistent delivery around surgery when cats may not accept oral medications.

Many customers save 60–80% vs typical U.S. prices. Those paying Onsior Solution without insurance often find cross‑border options lower than local retail. See our onsior solution coupon note on the promotions page for current offers if available.

Orders are shipped with prompt, express, cold‑chain handling to help protect product quality in transit.

Side Effects and Safety

• Common effects: vomiting, soft stool or diarrhea, reduced appetite, lethargy, and injection site tenderness.
• Less common: increased thirst or urination, behavioral changes, or transient elevations in liver enzymes on labs.
• Local reactions: mild swelling or warmth at the injection site may occur.
• Stop therapy and contact a veterinarian if there is persistent vomiting, black or bloody stool, marked lethargy, jaundice, or decreased urine output.
• Drug interactions: avoid combining with other NSAIDs, corticosteroids, or nephrotoxic drugs unless specifically directed by a veterinarian.

Serious risks are uncommon with short‑term use but can include gastrointestinal ulceration or perforation, kidney dysfunction (especially with dehydration, hypotension, or pre‑existing renal disease), and rare hypersensitivity reactions. Use caution in cats with liver disease, kidney disease, or a history of GI ulcer. Not for use in humans.

Onset Time

Analgesic effects generally begin within hours of injection as robenacoxib reaches inflamed tissues quickly. Many cats show improved comfort during the first post‑operative day. Inflammation and associated pain typically continue to subside over 1–3 days as tissues heal and dosing continues during the prescribed recovery period.

Compare With Alternatives

Onsior Solution is formulated for peri‑operative use when reliable dosing is needed at the clinic or during the immediate recovery window. Onsior tablets provide the same active ingredient in an oral form that may be used for short courses when a cat can take medication by mouth.

Meloxicam oral suspension is another NSAID option used in cats in some regions for post‑operative pain, typically as a single dose or short course per local labeling. It is less COX‑2 selective than robenacoxib and is often chosen based on clinician preference, patient history, and availability.

Adjunctive analgesics such as buprenorphine or gabapentin may be used alongside an NSAID for multimodal pain control after surgery. Selection depends on the type of procedure, the patient’s health status, and the need for additional sedation or anxiolysis during recovery.

Combination Therapy

• Do not combine with other NSAIDs (e.g., carprofen, meloxicam) or corticosteroids due to increased GI and renal risk.
• Often used with anesthetics, antibiotics, and IV fluids as part of a surgical protocol.
• Adjuncts such as buprenorphine or gabapentin may be added for multimodal pain control after surgery.
• Gastroprotectants (e.g., omeprazole) may be considered in higher‑risk patients per veterinary judgment.
• If therapy changes are needed, observe appropriate washout periods between NSAIDs under veterinary supervision.

Patient Suitability and Cost‑Saving Tips

Candidates include cats requiring short‑term management of pain and inflammation associated with soft‑tissue surgery. Clinical evaluation is needed before NSAID therapy, especially in older cats or those with concurrent disease.

Onsior Solution may not be appropriate for cats with active GI ulceration or bleeding, severe kidney or liver disease, dehydration, hypotension, coagulation disorders, or known NSAID hypersensitivity. Safety has not been established in breeding, pregnant, or lactating cats, or in very young or underweight kittens; follow labeled age and weight guidance from the prescribing veterinarian.

Cost‑saving tips:

• Plan quantities with the veterinarian for the expected recovery period to avoid waste.
• When appropriate, use tablets for at‑home days and the solution around surgery for efficient dosing.
• Order a few business days before a scheduled procedure so delivery is ready when needed.
• Consider multi‑vial packs if prescribed for multiple cats or procedures, where allowed.
• Watch seasonal promotions and manufacturer changes; pricing can vary by pack size and format.

Authoritative Sources

Health Canada Drug Product Database (DPD) – Product listings and monographs

U.S. FDA Center for Veterinary Medicine – Animal Drugs Search

Elanco – Company information on veterinary medicines

Order Onsior from CanadianInsulin: add to cart, upload your prescription, and we ship with prompt, express, cold‑chain handling.

This page is educational and is not a substitute for professional medical or veterinary advice. Always follow the prescribing veterinarian’s instructions and the product labeling.