Onsior® Solution for Postoperative Pain in Cats

Onsior Solution is a veterinary nonsteroidal anti-inflammatory drug used to control postoperative pain and inflammation in cats. It is available to US pet owners through CanadianInsulin and Ships from Canada to US. You can review options for Onsior Solution without insurance before you place a prescription request.

What Onsior Is and How It Works

Onsior® Solution injection contains robenacoxib, a selective cyclooxygenase-2 (COX-2) inhibitor. By targeting COX-2 more than COX-1, this medicine may reduce pain and swelling while helping preserve protective gastrointestinal and platelet functions. It is approved for subcutaneous administration in cats around the time of surgery to help manage acute post-surgical discomfort.

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As an NSAID, the treatment works best when given as directed by a veterinarian using preoperative or immediate postoperative timing. Your veterinary team may pair this injection with other perioperative measures, such as local anesthetics or multimodal analgesia, based on clinical judgment and current practice standards. For chronic joint disease in cats or pain control in dogs, your veterinarian may consider different products or oral regimens.

For more detail on surgery-related pain control in cats, see our category page on Feline Surgical Pain. You can also review background information on joint disease in both species in our article Arthritis in Pets.

Who It’s For

This injection is indicated for cats requiring pain control associated with soft tissue or orthopedic surgery. It may be used in healthy adult cats under veterinary supervision. The medicine is not labeled for use in dogs; your veterinarian can advise on canine alternatives when needed.

Pets with a history of gastrointestinal ulcers, bleeding disorders, dehydration, pre-existing kidney or liver disease, or poor cardiac function may face higher risks with NSAIDs. Do not use in breeding, pregnant, or lactating cats unless a veterinarian determines the benefit outweighs the risk. Avoid use if a cat is hypersensitive to robenacoxib or other NSAIDs.

Dosage and Usage

The injection is administered by a veterinarian as a single subcutaneous dose given near the time of surgery. Exact dosing is based on the cat’s weight and the official label. Do not administer this product at home unless your veterinarian provides clear instructions and supplies.

Give only as directed. Do not combine this class of drug with other NSAIDs or corticosteroids. If your cat is receiving other medicines, supplements, or topical products, tell your veterinary team. If you are unsure about timing with other perioperative treatments, defer to the label and your prescriber’s guidance. For label-specific reference, your clinic will determine the Onsior Solution dosage cats need using current product instructions.

Do not use in dehydrated or anorectic animals until stabilized. Ensure access to water. Report vomiting, diarrhea, or changes in appetite promptly to your veterinarian.

Strengths and Forms

This product is supplied as a sterile solution for injection at a commonly published concentration of Onsior Solution 20 mg/mL. Packaging and vial size may vary by manufacturer lot and market availability.

Missed Dose and Timing

Because this medicine is typically administered in the clinic, missed doses are uncommon. If your pet misses a scheduled surgical visit, contact your veterinarian to reschedule. Do not double-dose. If surgery timing changes, your clinician will adjust the medication plan.

Storage and Travel Basics

Store this medicine at room temperature in its original carton. Keep the container tightly closed and protect it from excessive heat, moisture, and direct light. Do not freeze. Keep out of reach of children and animals.

If your veterinarian dispenses a partial vial for later clinic use, follow their handling instructions. Do not puncture the container unless instructed and supplied with appropriate sterile syringes. When you travel with your pet, carry the prescription label, clinic contact details, and an itemized receipt. For longer trips, keep medicines in your hand luggage and avoid prolonged exposure to heat or cold.

Proper disposal of used syringes, if provided, follows local regulations. Use a puncture-resistant sharps container if any injections are administered outside the clinic and return the container per local guidance.

Benefits

As a COX-2 selective NSAID, this medicine can reduce surgical pain and inflammation in cats under veterinary care. The injectable route allows dosing at the clinic, which may simplify perioperative pain control. Using a single perioperative dose can support a multimodal plan that includes local anesthetics or systemic analgesics.

The class focus on COX-2 may help limit some gastrointestinal and platelet effects seen with less selective NSAIDs. Actual benefit varies by patient, procedure, and overall perioperative plan.

Side Effects and Safety

• Digestive upset: vomiting, soft stool, or diarrhea
• Reduced appetite or lethargy
• Injection-site pain or swelling
• Behavior changes such as hiding

Serious adverse events are uncommon but can include gastrointestinal ulceration or bleeding, kidney effects, liver enzyme changes, or allergic reactions. Cats with dehydration, kidney disease, or concurrent nephrotoxic drugs may be at increased risk. Stop the medicine and contact your veterinarian if you notice black stool, persistent vomiting, jaundice, facial swelling, or collapse.

Do not use with other NSAIDs or corticosteroids. Use caution with anticoagulants, certain blood pressure medicines, diuretics, and nephrotoxic agents. Inform your veterinarian about all medicines and supplements your pet receives.

Drug Interactions and Cautions

Avoid combining this treatment with other NSAIDs, corticosteroids, or aspirin due to additive gastrointestinal and renal risks. Use caution with diuretics, ACE inhibitors, angiotensin receptor blockers, or other drugs affecting renal blood flow. Monitor carefully if given near anesthesia or with potentially nephrotoxic antibiotics.

Use only in well-hydrated animals. Avoid use in cats with active bleeding, clotting disorders, or known NSAID hypersensitivity. If bloodwork reveals kidney or liver abnormalities, your veterinarian may recommend alternative analgesia.

What to Expect Over Time

After a clinic-administered dose, many cats show improved comfort during the immediate postoperative period. Eating, grooming, and mobility may become easier as surgical pain decreases. Your veterinarian may add oral analgesics for several days to sustain comfort.

Monitor appetite, water intake, and litter box habits at home. If your cat seems uncomfortable or develops digestive upset, contact the clinic. Follow recheck instructions and discuss any activity restrictions during recovery.

Compare With Alternatives

Other veterinary NSAIDs may be used for similar indications under a veterinarian’s direction. For perioperative use in cats, your clinician may consider Metacam Solution depending on local labeling and the patient’s status. For dogs with osteoarthritis pain, oral COX-2 selective options such as Previcox may be appropriate when prescribed. To learn more about one canine NSAID, see our article Deramaxx Guide.

Pricing and Access

We display transparent options so you can compare the Onsior Solution price with similar products. Because we source through licensed Canadian pharmacies, you may see Canadian pricing with US shipping from Canada. Check out securely and upload your prescription during checkout or have your clinic send it to us.

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Availability and Substitutions

Supply can vary. If this injection is temporarily unavailable, your prescriber may recommend a different NSAID or an oral form based on your pet’s needs and the surgical plan. For canine pain control, alternatives such as Rimadyl may be considered when appropriate.

Patient Suitability and Cost-Saving Tips

This treatment suits cats needing short-term postoperative pain control under a clinic’s supervision. It may not suit pets with significant kidney or gastrointestinal disease, or those on interacting medicines. Discuss your cat’s history, recent lab results, and all current medicines with the veterinarian before surgery.

To manage costs, ask about scheduling all required perioperative medications at once. If your cat will also need oral analgesics after discharge, combining items in a single order can reduce repeat fees. Set a calendar reminder to upload or request prescription transfers early, and keep original packaging for clear product identification during reorders. For broader shopping, browse our category pages on Pet Medications, Feline Arthritis, and Canine Surgical Pain.

Questions to Ask Your Clinician

• Is this NSAID appropriate for my cat’s surgery and health status?
• What signs of adverse effects should I watch for at home?
• Will my cat also need oral pain medicine after discharge?
• How should this medicine be timed with anesthesia and other drugs?
• What baseline bloodwork is recommended before and after treatment?
• What alternatives exist if my pet cannot receive an NSAID?
• Who should I contact for after-hours concerns post-surgery?

Authoritative Sources

For detailed prescribing information, your veterinarian may consult the manufacturer’s technical documents and regulatory approvals. You can review official resources here: the FDA Center for Veterinary Medicine product information for robenacoxib injection is available on the agency’s site at FDA CVM Animal & Veterinary. The Canadian Drug Product Database lists approved veterinary products and labeling; see Health Canada’s portal at Health Canada DPD. Manufacturer background information about robenacoxib and product support may be found on the company’s professional pages at Elanco US.

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Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.