Percorten-V® Injection for Canine Addison's Disease

What Percorten-V Is and How It Works

Percorten-V® contains desoxycorticosterone pivalate (DOCP), a mineralocorticoid used to manage hypoadrenocorticism (Addison’s disease) in dogs. It helps the body retain sodium and water and excrete potassium, which supports normal blood volume and electrolyte balance. Ships from Canada to US is available for qualified orders, and many customers compare options when paying without insurance.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

This medicine acts like aldosterone, restoring mineralocorticoid effects that are deficient in Addisonian dogs. It does not replace glucocorticoids, so some dogs may also need a separate steroid per your veterinarian’s plan. The treatment is given by injection on a repeating schedule, with dose and timing guided by clinical response and electrolyte monitoring.

Who It’s For

This treatment is for canine patients diagnosed with primary hypoadrenocorticism. It may also be used in stable dogs after an Addisonian crisis, once your veterinarian has corrected dehydration and electrolyte abnormalities. When discussing therapy options, many owners research percorten for dogs to understand long-term maintenance choices.

Do not use it in dogs with known hypersensitivity to DOCP. Use caution in patients with congestive heart failure, uncontrolled kidney disease, or significant edema, since the drug can increase fluid retention. Your veterinarian will determine if this mineralocorticoid is appropriate based on history, exam, and lab values.

For broader background on the condition itself, see our overview of Canine Addison’s Disease.

Dosage and Usage

The product is administered by subcutaneous injection at intervals typically measured in weeks. Initial dosing and adjustments are based on body weight, clinical signs, and serial electrolyte testing. Your veterinarian determines the starting dose and the interval between injections, then refines the plan over time.

Shake the vial well before drawing a dose, since this is a suspension. Administer the injection as instructed by your veterinary team, using aseptic technique with a new sterile needle and syringe each time. If your clinic provides at-home administration training, follow those steps carefully and record the injection date to aid monitoring.

Veterinarians may check sodium and potassium about midway through the first dosing interval and near the time a repeat dose is due. This helps tailor the schedule to the individual dog. In some cases, a small glucocorticoid dose may also be prescribed to cover cortisol needs.

Many owners search for percorten injection details; however, specific dose amounts and timing are individualized. Always follow your veterinarian’s directions and the product label.

Strengths and Forms

This medicine is supplied as an injectable suspension for dogs. The commonly available presentation is a multi-dose vial at 25 mg/mL, often in a 4 mL vial size. Actual availability and packaging can vary by pharmacy and lot.

On labels and professional references, it is described as desoxycorticosterone pivalate injectable suspension. Your veterinarian can advise if this strength and vial size are suitable for your dog and how many doses a vial may provide.

Missed Dose and Timing

If you miss a scheduled injection, contact your veterinarian for guidance as soon as possible. Do not double the next dose without professional advice. Timing adjustments are often based on clinical signs and electrolyte test results, so your veterinary team may recommend visit timing along with the next injection date.

If your dog shows signs suggestive of relapse such as weakness, vomiting, or collapse, seek urgent veterinary care. Early follow-up helps support safety when resuming therapy.

Storage and Travel Basics

Store the vial at room temperature as directed on the label, away from excess heat, moisture, and light. Keep the vial upright and secure the cap tightly after each use. Do not freeze, and keep out of reach of children and pets.

For travel, carry the vial in original packaging along with a copy of your prescription. Use a protective case to prevent breakage, and avoid prolonged temperature extremes such as a hot car interior. If flying, pack it in your carry-on and bring supplies like syringes only as permitted by airline policies and local rules. Ask your veterinarian for a travel note if you will cross borders with medication.

Pen Handling and Sharps Disposal

This product is not a prefilled pen. If you are instructed to give a percorten shot for dogs at home, draw the dose using a sterile syringe and needle, tap to release air bubbles as trained, and inject subcutaneously in a site recommended by your clinic.

Place used needles and syringes immediately into a puncture-resistant sharps container. Do not recap needles. When the container is three-quarters full, follow local rules for disposal through your veterinarian, pharmacy, or municipal program.

Benefits

This mineralocorticoid helps maintain normal sodium and potassium balance in dogs with Addison’s disease. It supports blood volume and hydration and can reduce episodes of weakness or collapse related to mineralocorticoid deficiency. The once-monthly schedule is convenient for many owners once stabilization is achieved.

Consistent dosing and regular monitoring can improve day-to-day stability. Many dogs do well long term when this therapy is paired with veterinary follow-up and owner observation.

Side Effects and Safety

• Increased thirst or urination
• Increased appetite or weight changes
• Mild injection-site discomfort
• Digestive upset such as vomiting or diarrhea
• Lethargy or restlessness

Serious or rare risks can include edema, worsening heart disease in predisposed dogs, or significant electrolyte shifts. Overexposure may lead to signs of fluid overload. Addisonian dogs may still require emergency care during stressful events. Contact your veterinarian promptly if you notice troubling symptoms such as persistent vomiting, collapse, labored breathing, or severe weakness.

Drug Interactions and Cautions

Tell your veterinarian about all medicines and supplements your dog receives. Interactions may occur with diuretics, ACE inhibitors, angiotensin receptor blockers, or drugs that affect potassium levels. Spironolactone may oppose mineralocorticoid effects. Corticosteroids are often co-prescribed but require careful coordination.

Use caution in dogs with heart disease, kidney impairment, or hypertension. Pregnant or breeding animals should be managed under close veterinary supervision. Periodic electrolyte testing helps guide safe long-term use.

What to Expect Over Time

After starting therapy, your veterinary team monitors electrolytes and clinical signs to fine-tune the dose and interval. Many dogs gradually stabilize, with improved energy, appetite, and hydration. The maintenance schedule can vary between individuals, and changes in health status may prompt adjustments.

Keeping a simple log of injection dates, appetite, water intake, and behavior can help your veterinarian interpret trends. Routine check-ins and lab work are an important part of ongoing care.

Compare With Alternatives

Another DOCP brand used for Addison’s control is Zycortal®, which your veterinarian may consider if clinically appropriate. Some dogs may use oral fludrocortisone instead of injectable mineralocorticoid therapy. Your veterinarian will compare options based on diagnosis, response, and owner preferences.

Pricing and Access

Owners often compare percorten price across pharmacies to plan ongoing care. Canadian pharmacy pricing can offer value, with US delivery supported for eligible prescriptions. Check the product page for current vial availability, order quantities, and checkout steps.

For seasonal deals and updates, visit our Promotions page. Checkout uses encrypted payment transmission, and our team supports coordination with your clinic when needed.

Availability and Substitutions

Supply can vary by distributor and lot. If an item is unavailable, your veterinarian may recommend a clinically appropriate alternative or a different fill size. Discussion of percorten v generic options is common; confirm current regulatory status and interchangeability with your veterinary professional before switching.

You can also browse related options in our Pet Medications section for additional veterinary products that your prescriber may recommend.

Patient Suitability and Cost-Saving Tips

This therapy suits dogs with confirmed hypoadrenocorticism who tolerate mineralocorticoid replacement. Dogs with significant heart failure, uncontrolled kidney disease, or severe edema require caution and closer monitoring. Your veterinarian will determine whether this medicine is appropriate and how to monitor safely.

To manage expenses, ask about multi-month ordering when permitted by prescription and storage. Set reminders for reorders so you don’t lapse between injections. Keep a small buffer of supplies like syringes and alcohol pads, and maintain clear records of dosing and lab visits.

Questions to Ask Your Clinician

• Monitoring plan: which electrolyte tests and how often
• Injection interval: how timing may change over time
• Signs to watch: what indicates over- or under-dosing
• Glucocorticoid needs: whether a separate steroid is required
• At-home injection: technique, sites, and safe handling
• Travel and storage: how to carry the vial safely

Authoritative Sources

For official product and regulatory details, consult these sources: see the manufacturer’s information on the Elanco site for veterinary professionals, the FDA Animal Drugs database for Percorten-V’s approval and labeling, and Health Canada’s Drug Product Database for Canadian listings where available. Review each resource for the most current label.

Manufacturer information is available from Elanco; see their professional product page on the Elanco website with veterinary product resources. Regulatory information is listed in the FDA’s database; see the FDA Animal Drugs page for Percorten-V labeling. Canadian listings can be searched via Health Canada; see the Drug Product Database search portal for official entries.

Ready to proceed? You can buy percorten v online through CanadianInsulin with prompt, express US delivery and temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.