Prascend (pergolide) Tablets

Prascend is a prescription pergolide tablet used in horses with pituitary pars intermedia dysfunction (PPID, often called equine Cushing’s disease). This page summarizes Prascend for horses with practical details on dosing basics, side effects, and storage so records stay consistent. For US shipping from Canada, requests can be handled as cash pay for those without insurance.

What Prascend for horses Is and How It Works

CanadianInsulin.com operates as a prescription referral service. The active ingredient in this treatment is pergolide, a dopamine agonist (dopamine-like medicine). In PPID, reduced dopamine signaling in the pituitary is linked to abnormal hormone activity. By stimulating dopamine receptors, pergolide can help reduce hormone overproduction associated with the disorder.

This medicine is intended for equine use under veterinary direction, and it is typically part of a broader plan that includes hoof care, nutrition, and monitoring for complications such as laminitis and infections. Clinical response is usually assessed by tracking both day-to-day changes and selected lab markers, rather than relying on a single observation. When reviewing general background on the condition, the site’s Equine Cushings Disease hub can be used as a browseable starting point for related items and context.

Who It’s For

This therapy is generally prescribed for horses diagnosed with PPID based on clinical signs, laboratory findings, and veterinary assessment. Common reasons a clinician may suspect PPID include abnormal hair coat shedding, changes in body condition, increased drinking or urination, recurrent infections, or a history of hoof pain consistent with laminitis. The goal is to address the endocrine (hormone-related) imbalance that contributes to these signs.

Use may be avoided in animals with known hypersensitivity to pergolide or other tablet ingredients. Extra caution can be appropriate in older, debilitated, or dehydrated horses, and in animals with significant concurrent disease, because appetite and hydration changes can become clinically important. A veterinarian should also review reproductive status and performance demands when selecting therapy. Documentation requirements and prescribing rules can vary by jurisdiction, so clinical eligibility is determined by the prescriber rather than by this page.

Dosage and Usage

Dosing for Prascend for horses is prescribed by a veterinarian and is adjusted to the individual animal’s weight, clinical response, and tolerance. Product labeling commonly describes a once-daily oral schedule, with titration based on follow-up assessment. Tablets are typically given by mouth, either directly or in a small portion of feed, and consistent timing helps with routine monitoring.

Why it matters: Missed doses and abrupt changes can complicate interpretation of symptoms and lab trends.

Monitoring and follow-up

PPID management often includes periodic clinical check-ins and targeted testing. One frequently used marker is ACTH (adrenocorticotropic hormone, a pituitary-related hormone), interpreted in context because reference ranges may vary by season and by laboratory method. In practice, monitoring also includes body weight or body condition scoring, water intake trends, hoof status, coat changes, and any episodes of colic-like discomfort. If appetite loss or marked lethargy appears after a dose change, the prescriber may reassess the regimen and rule out other causes.

For owners comparing supportive care options across different pet conditions, the article Arthritis In Dogs And Cats is a general example of how symptom tracking can guide follow-up discussions, even though the condition differs.

Strengths and Forms

This product is supplied as an oral tablet containing pergolide (pergolide mesylate). Prascend tablets are commonly listed as 1 mg strength, and some listings reference larger pack counts such as 160 tablets for longer courses. Availability can vary by dispensing pharmacy and by what is sourced for a given prescription.

The presentation is intended for accurate daily dosing and may allow careful splitting when the prescriber directs it, since dose adjustments are sometimes needed during titration. Tablet handling should follow the label and veterinary guidance, especially if tablets are split, because consistency matters when monitoring endocrine response over time.

Storage and Travel Basics

Store tablets according to the package instructions, typically in a dry place at controlled room temperature, protected from heat and moisture. Keep the container tightly closed and away from feed bins or areas with high humidity, since moisture exposure can affect tablet integrity. If the pharmacy supplies the medicine in a different container than the manufacturer packaging, keep any auxiliary labels and follow those directions.

Quick tip: Keep a simple log of dose time and clinical notes.

When traveling with Prascend for horses, keep doses in original labeled packaging and avoid leaving the container in a hot trailer or car. If tablets are split, store the remainder as directed and avoid mixing fragments from different dates without a clear system. Horses with PPID may also have concurrent issues that affect travel tolerance, so routine planning should include water access, feed consistency, and a plan for veterinary contact if appetite changes occur during transport.

Side Effects and Safety

When required, prescription information may be confirmed with the prescriber before dispensing. Like other dopamine-acting therapies, pergolide can cause side effects that range from mild appetite changes to more concerning signs. Not every horse experiences adverse effects, and symptoms can overlap with PPID itself or with other conditions, which is why careful observation and follow-up matter.

Some horses taking Prascend for horses may develop reduced appetite, mild depression, lethargy, diarrhea, or signs of abdominal discomfort. If these signs are persistent, severe, or accompanied by dehydration, prompt veterinary evaluation is important. A clinician may also consider whether the dose was changed recently or whether another illness is present.

• Common: appetite reduction, lethargy
• GI-related: diarrhea, colic-like signs
• Neurologic/behavioral: dullness, incoordination
• Escalation signs: dehydration, persistent pain

Because appetite and hydration can change quickly in equine patients, the prescriber may recommend a structured follow-up plan after starting therapy or after dose adjustments. For general medication-safety reading across the site, the guide Cephalexin Uses And Dosage illustrates how adverse-effect monitoring is typically framed, even though it covers a different drug class.

Drug Interactions and Cautions

Pergolide affects dopamine pathways, so medicines that block dopamine signaling may reduce its intended effect. Examples can include certain anti-nausea or gastrointestinal motility drugs and some tranquilizers; the veterinarian should review any current medications, supplements, and recent treatments before starting therapy. A complete list of interactions and precautions is contained in the official labeling.

Concurrent conditions can also influence tolerance. Horses with dental disease, chronic pain, or poor appetite may be more sensitive to appetite suppression, and dehydration can increase risk if gastrointestinal upset occurs. In clinical practice, the prescriber may also consider the timing of vaccinations, deworming, and major management changes, since multiple stressors at once can complicate interpretation of new signs. For a general example of how medication effects can vary with comorbidities, the resource Apoquel Uses And Side Effects discusses monitoring principles in another setting.

Compare With Alternatives

For PPID, pergolide is widely used and is the active ingredient in this brand. Alternatives may include other sources of pergolide, such as compounded formulations, but compounding quality and stability can vary and should be discussed with the veterinarian. In some cases, management-only approaches (diet changes, clip schedules, hoof care, and infection prevention) are used alongside medication, not as a direct substitute.

It also helps to distinguish equine PPID from canine hyperadrenocorticism (a different “Cushing’s” syndrome). For dogs with adrenal-based disease, trilostane is commonly used; see Vetoryl for the separate product category. If appetite loss or nausea becomes an issue during treatment, a veterinarian may consider supportive options such as maropitant; see Cerenia for the distinct antiemetic medication used in other species. Related background reading on maropitant is available in Cerenia Uses And Dosage.

Pricing and Access

Licensed Canadian pharmacies dispense medications after required documentation is in place. Total costs for this therapy can vary by strength, package count, and dispensing pharmacy policies, and longer courses may change the overall spend. When evaluating prascend cost considerations, it can help to compare the exact tablet count on the prescription and any requested refills, since pack sizes and refill frequency affect totals.

Prascend for horses is typically accessed with a valid prescription from a licensed veterinarian. For those managing cash-pay needs, the platform supports prescription-based access pathways that can be relevant when coverage is limited. Site-wide offers, when available, are listed on Current Promotions. For browsing other animal-health items on the site, Pet Medications is a category hub rather than a single product listing.

Authoritative Sources

The most reliable reference for dosing ranges, contraindications, and full safety information is the official label provided by regulators and the manufacturer. The links below are provided for neutral, primary-source context and may be updated over time.

• For U.S. regulatory listing details, see FDA Animal Drugs at FDA database.
• For manufacturer prescribing information, consult Prascend product information.
• For clinical background on PPID, review Merck Veterinary Manual PPID overview.

To proceed through the site, submit the prescription details and select prompt, express, cold-chain shipping at checkout if offered.

This content is for informational purposes only and is not a substitute for professional medical advice.