Revolution® Topical Solution for Dogs

What Revolution Is and How It Works

Revolution® is a prescription topical solution for dogs that prevents heartworm disease and controls fleas, ear mites, and sarcoptic mange. It uses selamectin, a macrocyclic lactone. This active ingredient targets parasite nerve and muscle function, which can lead to paralysis and death of susceptible parasites. As a monthly preventive, it interrupts reinfestation cycles when given consistently.

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This product is a Flea Infestation control that also protects against heartworm larvae transmitted by mosquitoes. It treats ear mites on the body surface and helps manage sarcoptic mange. The label for dogs also includes activity against the American dog tick. For broader tick protection, your veterinarian may recommend an additional tick-specific option.

As a once-monthly spot-on, revolution topical for dogs is placed on the skin at one site. The solvent carries selamectin across the skin barrier. Systemic absorption supports heartworm prevention, while topical concentrations target surface parasites.

Who It’s For

This treatment is indicated for dogs six weeks of age and older. It may be considered for households needing combined flea control, ear mite treatment, mange management, and heartworm prevention in one prescription product. Dogs with known hypersensitivity to any component should avoid use.

Use caution in underweight, debilitated, or sick animals. Discuss use if your dog has a history of neurologic disorders. Puppies should meet minimum age and weight requirements per the package insert. When used for heartworm prevention, revolution heartworm for dogs should be given monthly during mosquito season, and as directed in your region.

Dosage and Usage

Follow your veterinarian’s directions and the label. Apply the entire contents of the single-use tube to the skin once monthly. Part the hair at the base of the neck or between the shoulder blades until the skin is visible. Place the tip of the tube directly on the skin and squeeze to empty the full dose. Do not massage in; allow it to dry.

For selamectin for dogs, do not split tubes or substitute sizes across weight ranges. Keep treated animals separated until the application site is dry. Avoid contact with your eyes or mouth during administration. If a bath is needed, follow label timing guidance so the solution can dry fully before bathing or swimming.

Strengths and Forms

This product is supplied as single-use tubes of 6% selamectin topical solution. Tube volumes differ by your dog’s weight band. Common canine weight ranges include approximately 5–10 lb, 10–20 lb, 20–40 lb, 40–85 lb, and 85–130 lb (two appropriate tubes). Availability may vary by market and time of year.

Color-coded packs help identify the correct weight bracket. Your veterinarian will match the pack to your dog’s current weight. If your dog grows or weight changes, confirm the correct size before the next refill. For small-breed pets, revolution for small dogs corresponds to the lower weight bands.

Missed Dose and Timing

If a monthly dose is missed, give it when remembered and resume the regular schedule. For heartworm prevention lapses, consult your veterinarian about testing before restarting. Consistent monthly application helps keep fleas and ear mites under control and supports reliable prevention against heartworm larvae.

Avoid dosing more often than once monthly unless your veterinarian instructs otherwise. If multiple pets are treated, mark a calendar to keep dates aligned.

Storage and Travel Basics

Store in the original foil until use. Keep at room temperature as noted on the label, away from direct heat, flame, and sunlight. The solvent is flammable. Keep out of reach of children and other animals.

When you travel, pack sealed tubes in a leakproof pouch with your prescription details. Keep them in your carry-on if flying. Avoid extreme temperatures and protect tubes from puncture. For your storage, place used tubes out of reach until you can dispose of them properly.

Benefits

This medicine combines monthly heartworm prevention with flea control and ear mite treatment. It also treats sarcoptic mange and addresses a specific tick species in dogs. One topical dose per month simplifies parasite prevention for many households.

Using a single prescription item can reduce the number of separate products your veterinarian must coordinate. It may help adherence with a consistent monthly routine.

Side Effects and Safety

• Application site reactions: temporary hair clumping, mild redness, or dry skin
• Itching or mild hair loss at the site
• Digestive upset: soft stool or vomiting
• Lethargy or decreased appetite

Serious or rare events can include neurologic signs such as tremors, incoordination, or seizures. Hypersensitivity reactions are possible. Dogs with heavy parasite burdens may show transient signs as parasites die. Contact your veterinarian if you see concerning effects. If your dog is on insulin or sulfonylureas for diabetes, note that fleas can worsen skin irritation; while not a direct drug interaction, flea control may help overall skin comfort.

Drug Interactions and Cautions

Inform your veterinarian about all medications, supplements, and flea or tick products. Using multiple parasite treatments at the same time may increase skin irritation or other adverse effects. Macrocyclic lactones at labeled doses are generally well tolerated in most breeds.

Use as directed in heartworm-endemic areas. Dogs should have a negative heartworm test before starting a preventive regimen. Keep treated pets separated until the application dries to prevent accidental oral exposure.

What to Expect Over Time

With monthly use, you can expect sustained flea control and continuous heartworm prevention. Ear mite and mange signs may improve after treatment, though your veterinarian may recommend rechecks. Skin at the application site typically normalizes as the solvent evaporates.

Set reminders to dose on the same calendar day each month. If your veterinarian adjusts your prevention plan, follow their updated schedule.

Compare With Alternatives

Some dogs need broader tick coverage or a chewable format. Chewable isoxazolines like Simparica focus on fleas and ticks and are given monthly by mouth. Heartworm preventives like Interceptor Plus target heartworm and common intestinal worms. Revolution for Dog remains a topical, multi-parasite option that includes ear mite and mange indications. Your veterinarian can help match the choice to your dog’s risks and your preferences.

Pricing and Access

Canadian pricing may offer savings compared with some local options. You can review current options and place your order online with US shipping from Canada. If you need general guidance on affordability, see our overview in Buy Pet Medications.

Check your prescription to select the correct pack size. You can view available pack counts before adding to cart. Coupon availability can change; visit our Promotions page for current offers.

Availability and Substitutions

Availability can vary. If this item is out of stock, your prescriber may recommend a suitable alternative from the same class or a different prevention strategy. Do not switch products mid-cycle without veterinary guidance.

Patient Suitability and Cost-Saving Tips

This treatment may suit dogs needing combined flea control, ear mite therapy, sarcoptic mange treatment, and heartworm prevention in one prescription. It is not a fit for dogs with a known ingredient allergy. Puppies should meet label age requirements.

Ask your prescriber whether multi-month supplies are appropriate. Setting refill reminders helps maintain monthly protection. Consider aligning parasite prevention with calendar alerts for vaccines or wellness visits.

Questions to Ask Your Clinician

• Best product fit: topical vs. chewable for my dog
• Heartworm testing: timing before and during prevention
• Bathing guidance: how long to wait after dosing
• Tick risk: need for added tick-specific coverage
• Weight changes: when to switch tube sizes
• Household plan: treating all pets to break flea cycles

Authoritative Sources

For full prescribing details, see the manufacturer’s label and official resources: Zoetis product information for Revolution topical solution for dogs; FDA CVM Freedom of Information summary for selamectin; Health Canada Drug Product Database entry for selamectin.

For tick-related concerns, read our overview of species risk in Tick Infestation, and for ear mites see Ear Mite Infestation. For heartworm topics, see Canine Heartworm.

Order from CanadianInsulin with prompt, express, temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.