Revolution Plus® Topical Solution for Cats

A monthly topical solution for cats that targets common parasites. Revolution Plus offers broad coverage when used as directed. Ships from Canada to US with Canadian pricing for those paying without insurance.

What Revolution Plus Is and How It Works

Revolution Plus for cats is a prescription topical that combines selamectin and sarolaner in a single monthly tube. The actives distribute across the skin’s surface lipids and are absorbed in small amounts to reach parasites where they live. This combination provides broad protection against fleas, certain ticks, ear mites, roundworms, hookworms, and helps prevent heartworm disease.

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Selamectin targets susceptible internal and external parasites by interfering with their nerve and muscle function. Sarolaner affects specific ligand-gated chloride channels in arthropods, adding coverage for ticks and augmenting flea control. This medicine is applied to the skin at the base of the neck so the cat cannot lick the site.

Who It’s For

This treatment is indicated for cats and kittens at least 8 weeks of age and weighing 2.8 lb or more. It is intended for healthy cats requiring monthly prevention or control of fleas, certain ticks, ear mites, and some intestinal worms, and for the prevention of heartworm disease.

Do not use in kittens younger than 8 weeks or under 2.8 lb. Use caution in cats with a history of neurologic disorders, including seizures. Safety has not been established in breeding, pregnant, or lactating cats. Discuss your cat’s medical history with a veterinarian before starting a new therapy.

Dosage and Usage

The dose is based on body weight. Use the tube that matches the current weight, once a month, all year or as directed by the veterinarian. Part the hair and apply the entire contents to the skin at a single spot at the base of the neck. Do not massage the site. Wash hands after use, and avoid contact with the application site until dry.

Selamectin and sarolaner topical solution for cats is for external use only. Keep tubes away from children and other pets. Do not use more than one tube per month unless instructed by the prescriber.

Read the package insert before use. If a dose is due on a day with grooming, apply after the coat is completely dry.

Strengths and Forms

Single-use tubes in box sizes typically include three or six monthly doses. Availability can vary by market and supplier.

• 2.8–5.5 lb cats and kittens: one tube monthly.
• Revolution Plus for cats 5.6-11 lbs: one tube monthly matched to this weight band.
• 11.1–22 lb cats: use the tube labeled for this range; for cats over 22 lb, use the appropriate combination of tubes only as directed by a veterinarian.
• Common retail presentations include 3-dose and 6-dose boxes.

Missed Dose and Timing

If you miss a monthly dose, apply it when remembered. Resume the regular monthly schedule after that. Do not apply extra tubes to make up for a missed dose. Keeping a calendar or phone reminder can help maintain a consistent monthly date.

Storage and Travel Basics

Store at room temperature in the original foil pouches. Keep tubes capped and out of reach of children and animals. The contents are flammable; keep away from heat sources and open flame. Do not store in a hot car or near windows with direct sun. When traveling, carry the labeled carton or a copy of the prescription, and place tubes in a resealable bag to prevent leaks.

Benefits

Revolution Plus flea and tick for cats adds tick control to broad-spectrum protection compared with the original selamectin-only product. One monthly application simplifies parasite prevention across multiple targets.

• Broad coverage in a single monthly tube
• Flea control and prevention of infestations
• Certain tick species coverage
• Treatment of ear mites
• Treatment and control of roundworms and hookworms
• Heartworm disease prevention
• No pill for cats to swallow

Side Effects and Safety

• Application site issues: temporary hair loss, redness, or mild irritation
• Digestive signs: vomiting, soft stool, or decreased appetite
• Behavioral signs: lethargy or restlessness
• Drooling or pawing at the mouth if the application site is licked before drying

Serious but less common effects can include neurologic signs such as tremors or seizures, reported with isoxazoline class products. If you notice unusual behavior or persistent adverse events, contact a veterinarian. Keep the product away from the cat’s mouth and eyes, and do not use on broken skin.

Drug Interactions and Cautions

Tell the veterinarian about all medicines and supplements your cat receives. Using multiple parasite products with overlapping ingredients can increase exposure without added benefit. Extra caution may be warranted if other isoxazolines or macrocyclic lactones are used. Do not apply to wet fur or to cats that are ill or underweight without veterinary guidance.

What to Expect Over Time

With regular monthly use, the treatment may reduce flea burdens in the environment and help protect against re-infestation. Tick coverage adds an extra layer against outdoor exposure. Ear mite treatment typically requires the usual monthly schedule. For intestinal worms and heartworm prevention, ongoing monthly use is generally recommended per the label and veterinary advice.

Compare With Alternatives

Some cats may need a different spectrum or format. For rapid, single-dose flea knockdown without long residual, consider Capstar For Cat Dog. For another prescription topical covering fleas, ticks, and more, see Nexgard Combo. Your veterinarian can help choose based on lifestyle, indoor vs outdoor exposure, and worm risk.

Pricing and Access

Boxes are typically available in 3-dose or 6-dose supplies. Many customers prefer the Revolution Plus for cats 6 pack to reduce refill frequency. See current options and box sizes on this page, and check back for updates as supply changes. Enjoy US delivery from Canada with transparent Canadian pricing. If you pay cash or pay out of pocket, compare total costs to local retail or clinic pickup before you order. For broader selection across species, browse Pet Medications.

Availability and Substitutions

Supply can vary by weight range and box size. If the exact presentation you need is temporarily unavailable, the prescriber may recommend an alternative prevention plan. The 2.8–5.5 lb and 5.6–11 lb boxes are commonly stocked; the Revolution Plus for cats 11.1-22 lbs box may be stocked separately. There is no approved generic version of this combination in North America at this time. Zoetis is the manufacturer.

Patient Suitability and Cost-Saving Tips

This therapy suits healthy cats and kittens at least 8 weeks old meeting the minimum weight. It can be useful for indoor cats too, given possible exposure from people, other pets, or strays. Cats with skin disease at the application site or a history of seizures require caution and veterinary oversight. Consider a multi-month supply to reduce trips and help adherence. Set monthly reminders, and align dosing with a memorable date. If your veterinarian prescribes adjunct care for skin or ear issues, you can review related topics like Cat Medicine, Cephalexin For Dogs And Cats, and Pet Antibiotics Online to learn more about supportive treatments.

Questions to Ask Your Clinician

• Is this product appropriate for my cat’s age, weight, and health status?
• Which parasites are most relevant in my area and season?
• How should I time monthly dosing with grooming or bathing?
• What side effects should I watch for after application?
• Can my cat use this alongside other parasite preventives?
• What should I do if my cat weights change between visits?
• How long should my cat remain on year-round prevention?

Authoritative Sources

For full prescribing information and safety details, consult these official resources:

• Zoetis Product Page
• FDA DailyMed
• Health Canada DPD

Ready to proceed? Order from CanadianInsulin for prompt, express shipping with temperature-controlled handling when required and US shipping from Canada. This information is for general reference and does not replace guidance from your veterinarian.