Toujeo® SoloStar and DoubleStar Prefilled Pens for Diabetes

What Toujeo® Is and How It Works

Toujeo® is a long-acting insulin glargine 300 units/mL used as basal insulin for diabetes. At CanadianInsulin, you can review Canadian pricing and order from Canada with US delivery from Canada. If you pay without insurance, this page helps you compare options and choose the right prefilled pen for your prescription.

CanadianInsulin connects patients with licensed Canadian pharmacies. Prescriptions are verified with your clinic before dispensing.

As a U-300 formulation, Toujeo delivers the same insulin units in a smaller injection volume compared with U-100 basal insulin. After subcutaneous injection, insulin glargine forms a depot that releases slowly and evenly. This supports once-daily dosing and steady 24-hour or longer coverage when titrated correctly. Pens are designed for accurate dose delivery and do not require cartridge loading.

Both the SoloStar and DoubleStar devices are prefilled pens. Dose adjustments are measured in unit steps that match the pen type. Do not use Toujeo in an insulin pump, and do not mix it with other insulins. Learn more about the medicine in What Is Toujeo. Many patients choose to buy Toujeo SoloStar 300 Units/mL pens or Toujeo DoubleStar 300 Units/mL pens online with US shipping from Canada when permitted by their prescriber.

Who Toujeo® Is For

Toujeo is indicated to improve glycemic control in adults and in pediatric patients 6 years and older with diabetes mellitus. It provides background insulin for both type 1 and type 2 diabetes and is combined with mealtime insulin in type 1. For condition education, see our Type 2 Diabetes category.

Do not use Toujeo during episodes of diabetic ketoacidosis. It is for subcutaneous use only and is not for intravenous use or use in an insulin pump. Avoid if you have had a serious hypersensitivity to insulin glargine or any pen component. Use caution in patients with renal or hepatic impairment and in those at higher risk of hypoglycemia.

Dosage and Usage

Use Toujeo once daily, at the same time each day, or as directed by your prescriber. Dose is individualized and titrated based on fasting glucose and overall targets. For type 1 diabetes, Toujeo provides the basal portion of a calculated total daily insulin plan, with rapid-acting insulin given at meals. For type 2 diabetes, it is commonly initiated as basal therapy and adjusted gradually to meet fasting goals.

When switching from another basal insulin, your clinician will guide any initial conversion and subsequent titration. Because Toujeo is U-300, the unit-to-unit effect may differ from U-100 glargine and other basal insulins. Allow several days after a change before making further adjustments, unless safety issues arise. Do not dilute Toujeo and do not mix it with any other insulin.

For a deeper overview of titration practices and label-based adjustments, see Toujeo Dosage.

Strengths and Forms

• Concentration: 300 units/mL (U-300) insulin glargine
• Toujeo SoloStar prefilled pen: 1.5 mL per pen (total 450 units). Delivers 1-unit increments, up to 80 units per injection.
• Toujeo DoubleStar prefilled pen: 3 mL per pen (total 900 units). Delivers 2-unit increments, up to 160 units per injection.

Availability can vary. Your prescription will specify the pen type that fits your daily dose and the needed dose increments. If you are comparing Toujeo SoloStar 1.5 mL prefilled pen price with Toujeo DoubleStar 3 mL prefilled pen price, review the prescribed daily dose and expected monthly use when evaluating cost.

Missed Dose and Timing

Take Toujeo once daily at about the same time. If you miss a dose, check your blood glucose. Take the missed dose when you remember, as long as there is sufficient time before the next scheduled dose, and then resume your usual schedule. Do not take two doses at once. Follow your prescriber’s guidance if you have frequent missed doses or if readings are very high or very low.

Storage and Travel Basics

Keep unopened pens refrigerated in the original carton to protect from light. Do not freeze. Once in use, store the pen at room temperature as directed in the patient leaflet. Keep away from direct heat and sunlight. Never use a pen that has been frozen or overheated.

When traveling, carry your in-use pen and backups in hand luggage. Use insulated storage to avoid extreme temperatures. Pack extra needles and a sharps container or an approved travel alternative. For long trips, discuss backup plans for insulin and pen needles with your clinic.

Pen Handling and Sharps Disposal

• Read the pen’s Instructions for Use before the first injection.
• Always confirm the pen label says Toujeo 300 units/mL and the correct device name.
• Attach a new, sterile pen needle for each injection. Do not share pens or needles.
• Prime the pen before each use per the manufacturer’s steps to ensure insulin flow.
• Rotate injection sites within the same region to reduce the risk of lipodystrophy.
• After the dose, remove and discard the needle in an approved sharps container.
• Do not use Toujeo in an insulin pump and do not mix it with other insulin products.

If you are comparing delivery devices, you can review other Long Acting Insulin Pens to understand dosing increments and formats.

Benefits

• U-300 insulin glargine offers prolonged, consistent basal coverage when properly titrated.
• Smaller injection volume at the same unit dose compared with U-100 basal insulin.
• Prefilled pen convenience with no cartridge loading or reconstitution.
• Two pen options: SoloStar with 1-unit steps, DoubleStar with 2-unit steps for larger doses.
• Clear unit dialing and an audible click to support dose setting.

Benefits depend on correct dosing, injection technique, and regular glucose monitoring. Your prescriber may adjust dose over several weeks to stabilize fasting readings.

Side Effects and Safety

• Hypoglycemia
• Injection site reactions, including redness or irritation
• Lipodystrophy or localized skin changes at injection sites
• Edema
• Weight gain
• Rash or itching

Serious risks include severe hypoglycemia, severe allergic reactions, hypokalemia, and fluid retention, especially when used with thiazolidinediones. Do not drive or operate machinery if your glucose is low or if you feel impaired. Insulin use with SGLT2 inhibitors has been associated with ketoacidosis even with normal or near-normal glucose. Seek urgent care for severe symptoms. For a practical overview, read Toujeo Side Effects.

Drug Interactions and Cautions

• Drugs that may increase hypoglycemia risk: other antidiabetic agents, GLP-1 receptor agonists, SGLT2 inhibitors, ACE inhibitors, and alcohol.
• Drugs that may raise glucose: corticosteroids, diuretics, sympathomimetics, some antipsychotics.
• Beta blockers may mask some hypoglycemia symptoms.
• Use caution with thiazolidinediones due to fluid retention and heart failure risk.
• Illness, reduced food intake, or increased activity may require dose review.

Always share your full medication and supplement list with your clinician and pharmacist. Do not change your insulin dose on your own.

What to Expect Over Time

After starting or switching, glucose values usually stabilize as the dose is titrated. Many people see fasting numbers improve first, followed by gradual improvements in overall averages. Your prescriber will set targets and adjust your plan at follow-up. Continue meal planning, activity, and glucose monitoring to support the insulin plan. Consistency with injection timing and site rotation supports predictable results.

Compare With Alternatives

Your prescriber may consider other long-acting insulins. Insulin glargine U-100 is available as Lantus® SoloStar Pens, which use 1-unit steps. Insulin degludec is available as Tresiba® FlexTouch Pens, which offer flexible dosing and very long duration. Combination basal-bolus or basal-plus strategies can also be planned using separate rapid-acting insulin, as directed by your clinician.

Pricing and Access

Review Toujeo pens Canadian pricing on this page and compare forms based on your prescribed dose. Many patients compare Toujeo SoloStar prefilled pen cost with Toujeo DoubleStar prefilled pen cost to match monthly needs. You can order Toujeo SoloStar pen online or order Toujeo DoubleStar pen online with US shipping from Canada after your prescription is confirmed. If you are comparing Toujeo price without insurance or checking Toujeo cash price, use the pricing tools to estimate your out-of-pocket total. For occasional deals, visit our Promotions page.

We process US delivery from Canada after verification with your clinic. Taxes, dispensing fees, and shipping are shown at checkout before you place your order.

Availability and Substitutions

Stock can vary by strength and device. If Toujeo pens are unavailable, your prescriber may recommend an appropriate alternative or a temporary substitution within the long-acting insulin class. We cannot guarantee restock dates. Your care team should oversee any change to avoid hypoglycemia or loss of control.

Patient Suitability and Cost Saving Tips

• Suitable for adults and for children 6 years and older when prescribed.
• Not for DKA, intravenous use, or use in an insulin pump.
• SoloStar suits patients needing 1-unit titration steps. DoubleStar suits higher daily doses requiring 2-unit steps.
• Ask about multi-month supplies to reduce per-pen shipping costs.
• Set refill reminders so you do not run out during travel or holidays.
• Discuss realistic fasting targets and titration intervals to avoid frequent dose changes.

Questions to Ask Your Clinician

• Which pen suits my dose: SoloStar 1-unit steps or DoubleStar 2-unit steps?
• How should I titrate safely to reach my fasting glucose target?
• What signs of hypoglycemia should I watch for, and how should I treat it?
• How do sick days affect my Toujeo dose and monitoring plan?
• What should I do if my daily dose exceeds a single injection limit?
• How should I rotate injection sites to prevent skin changes?
• Are there interactions with my current medicines or supplements?

Authoritative Sources

• FDA DailyMed Toujeo
• Sanofi Toujeo Product Page
• Health Canada Drug Product Database

Ready to proceed? Place your Toujeo pens order for US delivery from Canada with prompt, express, cold-chain shipping.