Please note: a valid prescription is required for all prescription medication.
Tresiba® FlexTouch pens are prefilled insulin pens for basal insulin degludec. This ultra long-acting insulin supports stable, once-daily dosing for diabetes care. You can buy it from Canada with US delivery, including cash-pay options without insurance.
What Tresiba® Is and How It Works
Tresiba® contains insulin degludec, a long-acting basal insulin. It helps control fasting and between-meal blood glucose in adults and children. The action is smooth and prolonged, designed for once-daily use at a consistent time.
At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.
Tresiba supports flexible timing if needed. When a schedule change is required, many patients can adjust dose timing while keeping at least several hours between injections per the label. It is used alone or with other antidiabetic medicines. It is not for treating diabetic ketoacidosis.
US delivery from Canada helps many patients access Canadian pricing. This cross-border option can reduce out-of-pocket cost for insulin therapy.
Who Tresiba® Is For
Tresiba is indicated for adults with type 1 or type 2 diabetes. It is also approved for pediatric patients one year and older. It provides background insulin to manage fasting glucose.
Do not use Tresiba if there is an ongoing episode of hypoglycemia. Do not use if there is a known allergy to insulin degludec or any pen component. Tresiba is not for intravenous use and is not for insulin pumps. It is not mixed with other insulins.
People with kidney or liver problems may need closer monitoring. Pregnancy and breastfeeding require individualized care. Discuss risks and benefits with a clinician.
For those who need a long-acting pen format, see our selection of Long Acting Pens.
Dosage and Usage
The dose is individualized. Many adults with type 2 diabetes start at 10 units once daily. Titration often occurs every few days, guided by fasting blood glucose. Changes are usually small and steady until targets are reached. Always follow your prescriber's plan and the official label.
For type 1 diabetes, Tresiba provides the basal part of a multiple daily injection regimen. Rapid-acting insulin is used for meals and corrections. The basal share of total daily insulin varies by patient and clinical goals.
Tresiba is given subcutaneously once per day, at the same time if possible. If timing must change, keep a safe interval between doses as directed on the label. Rotate injections among abdomen, thigh, or upper arm areas to reduce skin changes.
When switching from another basal insulin, unit-for-unit conversion may apply in many cases. However, some switches require dose adjustments. Your prescriber will set the plan.
Strengths and Forms
Common Tresiba FlexTouch presentations include:
- U-100 (100 units/mL) 3 mL prefilled FlexTouch pens
- U-200 (200 units/mL) 3 mL prefilled FlexTouch pens
- Typical packaging: multi-pen packs; availability may vary
Device limits help plan larger doses:
- U-100 pen generally delivers up to 80 units in a single injection
- U-200 pen generally delivers up to 160 units in a single injection
Selection between U-100 and U-200 depends on dose volume, injection burden, and clinician guidance.
Missed Dose and Timing
If a dose is missed, take it when remembered, then resume the regular schedule. Keep at least 8 hours between injections. Do not take extra insulin to make up a missed dose. Review the label for specific instructions and call your clinic if uncertain.
Storage and Travel Basics
Unopened pens are typically stored in the refrigerator. In-use pens can be kept at room temperature for a limited period per the official label. Protect from heat and light. Do not freeze. Do not use if insulin has been frozen.
Keep the pen cap on when not in use. Avoid leaving insulin in a hot car or direct sunlight. For travel, use an insulated case. You can carry pens in a personal item through airport security. Keep a spare pen and extra needles. Pack a copy of your prescription.
During warmer seasons, temperature control in transit helps maintain quality. Shipping from Canada may use cold-chain methods when appropriate.
Pen Handling and Sharps Disposal
Read the Patient Instructions for Use that come with the FlexTouch pen. General steps are below and do not replace the device guide:
- Check the label to confirm Tresiba and the correct strength
- Inspect insulin; do not use if cloudy, colored, or contains particles
- Attach a new sterile needle for each injection
- Prime the pen as directed to ensure insulin flow
- Dial the prescribed dose
- Choose an approved injection site and clean the skin
- Insert the needle and press the button steadily
- Keep the needle in place for several seconds to complete delivery
- Remove the needle and apply gentle pressure if needed
- Dispose of the needle safely in an FDA-cleared sharps container
For a step-by-step refresher, see our Tresiba® FlexTouch Guide. Never reuse or share needles or pens.
Benefits
- Ultra long-acting basal insulin with a smooth profile
- Once-daily dosing for most patients
- Flexibility to adjust timing when needed, per label
- Prefilled pen convenience with clear dose dialing
- Option for higher-strength U-200 to reduce injection volume
- Suitable for adults and pediatric patients one year and older
Side Effects and Safety
- Hypoglycemia (low blood sugar)
- Injection site redness, swelling, or itching
- Lipodystrophy or skin thickening at injection sites
- Weight gain or fluid retention
- Allergic reactions, including rash
- Nasopharyngitis or mild respiratory symptoms
Serious reactions are uncommon but can include severe hypoglycemia, significant allergic reactions, and worsening fluid retention when combined with certain agents. Hypoglycemia risk increases when Tresiba is used with other drugs that lower glucose, such as sulfonylureas or prandial insulin. Seek medical care for severe or persistent symptoms. For more details, review our overview of Tresiba® Side Effects and the official label.
Drug Interactions and Cautions
Some medicines may increase or decrease insulin needs. Common examples include steroids, certain oral diabetes medicines, GLP-1 agonists, beta-blockers, diuretics, and thyroid medicines. Alcohol can increase the risk of hypoglycemia. Thiazolidinediones used with insulin may increase fluid retention and heart failure risk. Always check with a clinician before starting or stopping medicines.
Illness, stress, or changes in activity can also affect insulin needs. Monitor glucose and follow clinician guidance.
What to Expect Over Time
Tresiba builds a steady basal effect with consistent daily use. Fasting glucose typically becomes more stable as dose adjustments progress. Many people see fewer overnight swings compared to some shorter-acting basal options. Individual responses vary. Clinicians may fine-tune dose over several weeks to reach agreed targets.
Compare With Alternatives
Several other long-acting basal insulins are available. Insulin glargine is a common alternative. Consider Lantus® SoloStar Pens for a widely used glargine option. A higher-strength glargine may suit higher daily doses; see Toujeo® DoubleStar Pen. Some patients may also use combination therapy like insulin glargine with lixisenatide or other agents based on clinical goals. Your prescriber can determine the most appropriate basal regimen.
Pricing and Access
Canadian pricing with US delivery can lower the overall cost of basal insulin. Many customers compare the price of U-100 versus U-200 pens to optimize value. You can check current cost and place your order securely online.
To maximize savings, review available offers on our promotions page. Prices can vary by strength and pack size.
If you prefer to browse related options first, explore our full range of Insulin Products.
Availability and Substitutions
Stock levels can change. If an item is unavailable, a prescriber may recommend an appropriate alternative basal insulin. Pharmacy substitution rules for insulin vary and often require prescriber approval. There is no direct generic for insulin degludec pens at this time. Availability may differ between U-100 and U-200 strengths.
Patient Suitability and Cost Saving Tips
Tresiba may be appropriate for patients needing a long-acting basal profile with once-daily dosing. It is not for emergency treatment or diabetic ketoacidosis. It is not used in insulin pumps and is not mixed with other insulins. Pediatric use is approved for those one year and older when prescribed.
- Ask about U-200 if doses are high, to reduce injection volume
- Consider multi-month supplies to cut refill trips
- Set refill reminders to avoid gaps in therapy
- Store pens correctly to prevent waste
- Use a consistent injection routine to support stable control
Questions to Ask Your Clinician
- Is Tresiba the right basal insulin for my goals?
- Should I use U-100 or U-200 based on my dose?
- How should I titrate safely toward my fasting glucose target?
- What should I do if my injection time needs to change?
- Which rapid-acting insulin pairs best with my basal plan?
- How can I recognize and treat low blood sugar promptly?
- Which other medicines might affect my insulin needs?
Authoritative Sources
| Reference | Link |
|---|---|
| FDA DailyMed – Tresiba (insulin degludec) injection | DailyMed |
| Novo Nordisk – Tresiba product information | Manufacturer |
| Health Canada – Drug Product Database | Health Canada DPD |
Ready to start? Order Tresiba FlexTouch from Canada for US delivery with secure checkout.
Disclaimer: This page is informational and not a substitute for medical advice. Always follow your prescriber and the official product label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What is Tresiba FlexTouch and what does it treat?
Tresiba FlexTouch is a prefilled pen that delivers insulin degludec, an ultra long-acting basal insulin. It helps control fasting and between-meal blood sugar in adults and children with diabetes.
How often is Tresiba taken and when should it be used?
Tresiba is injected subcutaneously once daily at the same time if possible. The dose is individualized. Some patients can adjust timing when needed, keeping a safe interval between doses per the label.
What is the difference between Tresiba U-100 and U-200 pens?
Both contain insulin degludec. U-200 is twice as concentrated, which reduces injection volume. U-100 pens generally deliver up to 80 units per injection; U-200 pens generally deliver up to 160 units.
What should I do if I miss a Tresiba dose?
Take the missed dose when remembered, then resume the regular schedule. Keep at least 8 hours between doses. Do not take extra insulin to make up a missed dose. Check the label or call your clinic if unsure.
How long can an opened Tresiba pen be used?
In-use Tresiba pens can be kept at room temperature for a limited period as stated on the label, commonly up to 8 weeks. Protect from heat and light. Do not refrigerate a pen in use.
Can Tresiba be mixed with other insulins or used in a pump?
No. Tresiba is not mixed with other insulins and is not for insulin pumps. It is injected subcutaneously with the FlexTouch pen as directed.
Do you ship Tresiba from Canada to the US?
Yes. Orders ship from Canada to US addresses after prescription verification. Temperature control is used when appropriate. Exact timelines vary by carrier and are not listed here.
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