Join now & save up to 80% on medication

JOIN NOW
Select Language:

Join now and save 80% on medication

Register/Login

Glyburide and Hypoglycemia

Share Post:

What is Glyburide ?

Glyburide belongs to the group of second-generation sulfonylureas—a type of medication that is used to treat type 2 diabetes. People with type 2 diabetes has high sugar levels in their blood because their bodies cannot properly store excess sugar. Sulfonylureas were among the first oral medications developed for high blood sugar levels. They are generally well-tolerated and less expensive.

Insulin is an essential hormone that allows the body to turn sugar from food into energy or store it for future use. Glyburide works by stimulating the pancreas to release more insulin into the bloodstream and into the cells to provide energy; eventually lowering the blood sugar level. An important concern regarding the use of anti-hyperglycemic drugs is their ability to cause hypoglycemia (low blood sugar level). Hypoglycemic attacks are dangerous because they can lead to seizures, loss of consciousness, and even death.

Symptoms of Hypoglycemia

  • Sweating
  • Extreme hunger
  • Dizziness
  • Shakiness
  • Rapid heart rate
  • Blurred vision
  • Weakness
  • Headache
  • Unconsciousness

Glyburide and Hypoglycemia

Several studies suggest that glyburide is associated with more hypoglycemic attacks than most sulfonylureas. Additionally, this medication is contraindicated in patients with renal impairment or severe hepatic impairment because of the high risk of hypoglycemia.

Results from other notable studies:

  1. Glyburide can be a therapeutic option for women with gestational diabetes mellitus, but it is currently not approved for such indication.
  2. A meta-analysis of 21 studies revealed that patients receiving glyburide has a 52% higher risk of hypoglycemia than those taking other insulin medications.
  3. When compared with other second-generation sulfonylureas, hypoglycemia occurred twice as often in patients receiving this drug than those taking glipizide.
  4. The higher risk of hypoglycemia in glyburide is not associated with lower glycated hemoglobin values (HbA1c); the average glucose concentration in the plasma that is useful in diagnosing diabetes.
  5. Patients receiving glyburide, except those with gestational diabetes mellitus, may be switched to glimepiride or glipizide.

You can check Glyburide cost at canadianinsulin.com.


Disclaimer: Please note that the contents of this community article are strictly for informational purposes and should not be considered as medical advice. This article, and other community articles, are not written or reviewed for medical validity by Canadian Insulin or its staff. All views and opinions expressed by the contributing authors are not endorsed by Canadian Insulin. Always consult a medical professional for medical advice, diagnosis, and treatment.
Profile image of CDI Staff Writer

Written by CDI Staff WriterOur internal team are experts in many subjects. on April 11, 2022

Related Products

Promotion
Ozempic
  • In Stock
  • Express Shipping
New Lower Price
Mounjaro Vial
  • In Stock
  • Express Shipping
Promotion
Rybelsus
  • In Stock
  • Express Shipping
Bulk Savings
Humalog Vial
  • In Stock
  • Express Shipping

Related Articles

Diabetes, Type 2
Buy Glumetza from Canada: Tips for Lower Prescription Costs

Managing type 2 diabetes often means balancing not only your health but also your healthcare expenses. Medications such as Glumetza, an extended-release form of metformin, play a critical role in…

Read More
Type 2 Diabetes,
How to Avoid Ozempic Face: Simple Strategies That Work

According to the National Institutes of Health (NIH), diabetes affects over 37 million Americans. While Ozempic helps many manage blood sugar and weight, a cosmetic concern called Ozempic face is…

Read More
Diabetes, Type 2
Mounjaro Face: Why It Happens and What to Do

Weight loss medications like Mounjaro (tirzepatide) are transforming the way people manage type 2 diabetes and obesity. While many celebrate the success of shedding pounds, some notice changes in their…

Read More
Diabetes, Diabetes Supplies,
Lantus Insulin Cartridge: Simple, Steady Blood Sugar Control

Research shows that 8.4 million Americans rely on insulin to manage diabetes, and many are looking for ways to make treatment simpler. The Lantus insulin cartridge, designed for use with…

Read More