Invokana® Tablets for Type 2 Diabetes

Invokana® is a prescription SGLT2 inhibitor used to improve blood sugar control in adults with type 2 diabetes. This page explains how the medicine works, who it may suit, and key safety and access details to help with informed ordering. You can review options for US delivery from Canada and consider costs without insurance.

What Invokana Is and How It Works

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This medicine contains canagliflozin, an SGLT2 inhibitor. It lowers renal glucose reabsorption so more glucose passes into the urine, which may reduce A1C over time. The treatment can also lead to mild diuretic effects, such as increased urination, and small reductions in weight and blood pressure for some patients.

Buy Invokana online is available with a valid prescription. The tablets are generally taken once daily before the first meal to align with renal glucose transport activity. Labeling notes additional benefits in adults with type 2 diabetes and established cardiovascular disease or diabetic kidney disease, where outcome data support risk reduction in specific complications.

Who It’s For

This therapy is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It may also be used in adults with type 2 diabetes and certain cardiovascular or kidney conditions, as described in the approved labeling. For background on the condition, see our overview of Type 2 Diabetes.

It is not for type 1 diabetes or for treatment of diabetic ketoacidosis. Avoid use if you are on dialysis or have a history of serious hypersensitivity to canagliflozin. People with severe renal impairment, volume depletion, or recurrent genital mycotic infections should discuss risks and alternatives with a clinician.

Dosage and Usage

The usual starting dose is 100 mg once daily, taken before the first meal of the day. Depending on kidney function and tolerability, some patients may be increased to 300 mg once daily. The official label provides eGFR-based recommendations and limits; follow your prescriber’s directions.

Take the tablet whole with water. Maintain hydration, especially during illness or hot weather, to reduce the chance of dizziness or dehydration. If you use insulin or a sulfonylurea, your clinician may monitor for hypoglycemia and adjust therapy according to the label and clinical judgment. Suspend therapy and seek care if symptoms of ketoacidosis occur, even if glucose is not dramatically elevated.

Strengths and Forms

Film-coated oral tablets are commonly available in these strengths:

• 100 mg tablets
• 300 mg tablets

Availability can vary by pharmacy and supply status.

Missed Dose and Timing

If a dose is missed, take it the same day when remembered. If it is nearly time for the next dose, skip the missed dose and resume the regular schedule. Do not double up to make up for a missed tablet.

Storage and Travel Basics

Store tablets at room temperature in a dry place and keep the bottle tightly closed. Protect from excess moisture and keep out of reach of children and pets. Do not use tablets that are damaged or expired.

When traveling, carry the medication in the original labeled container and pack it in your carry-on. Bring a copy of your prescription or a medication list. If crossing borders, allow extra time for routine screening, and keep your prescriber’s contact details available.

Benefits

This medicine helps lower blood glucose and A1C when used with diet and exercise. It can reduce urinary glucose thresholds, which may support modest weight and blood pressure reductions. In patients with type 2 diabetes and certain comorbidities, outcome data support benefits in cardiovascular and kidney endpoints as described in the prescribing information.

Side Effects and Safety

• Genital yeast infections: itching, discharge, or irritation
• Urinary tract infections: burning or urinary frequency
• Increased urination or thirst
• Nausea or constipation
• Dizziness, especially with low fluid intake

Serious but less common risks include ketoacidosis, severe urinary infections (urosepsis, pyelonephritis), volume depletion with low blood pressure, acute kidney injury, hyperkalemia in susceptible patients, bone fractures, and rare necrotizing fasciitis of the perineum. An increased risk of lower-limb amputations has been observed; discuss foot care, peripheral vascular disease, and neuropathy risks with your clinician. Seek medical help for severe abdominal pain, vomiting, confusion, fever, or signs of infection.

Drug Interactions and Cautions

Diuretics and antihypertensives can amplify volume depletion and orthostatic dizziness. Insulin and sulfonylureas can raise the chance of hypoglycemia when combined with SGLT2 inhibitors. Enzyme inducers such as rifampin may reduce canagliflozin exposure. Canagliflozin may increase digoxin levels; monitor as directed. Review all prescription medicines, OTC products, and supplements with your healthcare provider.

Hold the drug around major surgery or prolonged fasting per clinician advice to lower ketoacidosis risk. Monitor renal function and volume status periodically, especially in older adults or those on diuretics or RAAS blockers.

What to Expect Over Time

Glucose effects often begin within days, with fuller A1C assessment at routine follow-up. Urination may increase, especially early in therapy. Adherence to diet, hydration, and consistent timing can help maintain stable results.

If budgeting for therapy, compare the Invokana retail price with Canadian options and consider multi-month planning. Track symptoms, foot health, and infections, and report concerns promptly. Routine labs, including kidney function and lipids, may be checked according to the label and clinical practice.

Compare With Alternatives

SGLT2 inhibitors have class similarities but differ in dosing and labeled outcomes. Empagliflozin, available as Jardiance®, is another option for glycemic control and certain cardiovascular indications. Dapagliflozin, offered as Farxiga®, has indications that include glycemic control and additional labeled uses. Your prescriber can help match therapy to comorbidities and goals.

Combination therapy with metformin may be considered if a single agent does not meet targets. Some patients use a GLP-1 receptor agonist or metformin first, then add or switch based on effects and tolerability.

Pricing and Access

We list current options to help you compare invokana price and supply preferences. Canadian pricing often differs from local cash rates, and options Ships from Canada to US with a valid prescription.

For those paying cash, you can review Invokana price without insurance alongside formulary information from your plan. If your prescriber approves, a longer fill can reduce per-tablet cost and lower the number of refills. Checkout uses encrypted processes to protect your information.

To explore limited-time offers, see our Promotions page.

Availability and Substitutions

Supply can vary by strength and package size. If a specific option is unavailable, your prescriber may recommend a comparable SGLT2 inhibitor or a metformin combination. For insured beneficiaries, Invokana cost with Medicare varies by plan design, tier placement, and pharmacy network—verify coverage with your insurer.

If a substitution is needed, your clinician will decide if a class alternative is appropriate based on kidney function, comorbidities, and prior response. For background on SGLT2s, see our category page for SGLT2 Inhibitors.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults with type 2 diabetes needing additional glycemic control, particularly those with certain cardiovascular or renal risks noted on the label. It is not appropriate for type 1 diabetes or for people with active ketoacidosis. Discuss recent amputations, severe peripheral vascular disease, neuropathy, or frequent genital infections with your clinician before starting.

• Multi-month fills: fewer refills and potential unit-cost savings
• Refill reminders: set calendar alerts to avoid gaps
• Therapy pairing: review insulin or sulfonylurea dosing to reduce lows
• Foot care plan: inspect skin and nails; report ulcers early
• Strength planning: compare Invokana 100 mg price when discussing dose

For broader diabetes options, browse our Diabetes category or the Medications section for non-insulin therapies.

Questions to Ask Your Clinician

• Is an SGLT2 inhibitor appropriate for my kidney function and goals?
• How should I monitor for dehydration, infections, or ketoacidosis symptoms?
• Do I need changes to insulin or sulfonylurea doses when starting?
• What lab tests and foot checks should I schedule?
• Which sick-day rules and surgery hold times apply to me?

Authoritative Sources

For full prescribing details, consult these official resources:

• DailyMed drug label for canagliflozin with dosing and safety
• FDA prescribing information describing indications and warnings
• Health Canada database entry for Invokana with product details

Learn more about this class and comparisons in our articles, including Canagliflozin Uses, Side Effect Tips, and Generic Options.

Order when ready from CanadianInsulin with prompt, express, temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.