Invokana® Tablets for Type 2 Diabetes

Invokana® (canagliflozin) is an SGLT2 inhibitor tablet for adults with type 2 diabetes. CanadianInsulin offers access from Canada with US delivery from Canada and Canadian pricing, helping people compare Invokana price and options without insurance. This page explains how it works, who it fits, dosing, safety, and how to arrange shipping.

What Invokana® Is and How It Works

Invokana® is the brand name for canagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It lowers blood glucose by blocking glucose reabsorption in the kidneys, which increases urinary glucose excretion. Many patients also see modest reductions in body weight and blood pressure. US shipping from Canada is available through our service.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.

Invokana is approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It also reduces the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease. In adults with type 2 diabetes and diabetic kidney disease with albuminuria, it reduces the risk of serious kidney outcomes and certain cardiovascular events.

Its SGLT2 action works in the proximal renal tubules, independent of insulin. This helps lower fasting and post-meal glucose. The diuretic effect can also lower systolic blood pressure. Effects vary by individual and by kidney function.

Who Invokana® Is For

Invokana is indicated for adults with type 2 diabetes. It supports glucose control alongside diet and exercise. It may also be appropriate for adults with type 2 diabetes who have established cardiovascular disease, or for those with diabetic kidney disease and albuminuria, when prescribed for risk reduction. See our category for broader options in Type 2 Diabetes.

Invokana is not indicated for type 1 diabetes or for the treatment of diabetic ketoacidosis. It is not recommended in patients on dialysis. People with very low blood pressure, severe dehydration, or a history of severe hypersensitivity to canagliflozin should avoid it.

Caution is advised for those with peripheral vascular disease, neuropathy, or foot ulcers due to an observed amputation risk in trials. Clinicians consider individual risks and benefits, including kidney function, prior to starting therapy.

Dosage and Usage

The typical starting dose is 100 mg once daily, usually before the first meal of the day. If additional glycemic control is needed and kidney function permits, the dose may be increased to 300 mg once daily. Dose limits depend on estimated glomerular filtration rate (eGFR); clinicians adjust based on labs, response, and tolerability.

Hydration status matters. Volume depletion can increase side effects like dizziness or low blood pressure. Temporary interruption is considered during acute illness, reduced oral intake, or prior to surgery to reduce ketoacidosis risk.

For a structured overview of labeled schedules, titration, and eGFR considerations, see Invokana Dosage. Always follow the prescribing clinician’s instructions and the official label.

Strengths and Forms

Invokana is available as film-coated oral tablets:

• 100 mg tablets
• 300 mg tablets

Availability may vary by pharmacy and market.

Missed Dose and Timing

Invokana is usually taken once daily prior to the first meal. If a dose is missed, take it when remembered unless it is close to the time of the next dose. Do not take two doses at once. If uncertain, follow the guidance on the prescription label or contact the prescriber or pharmacist.

Storage and Travel Basics

Store tablets at room temperature, typically 20°C to 25°C (68°F to 77°F). Keep the bottle tightly closed and away from moisture. Do not store in a bathroom. When traveling, keep medicine in original packaging in carry-on luggage. You can store your order promptly upon delivery.

Benefits

Label-supported benefits include:

• Improved glycemic control in adults with type 2 diabetes when used with diet and exercise
• Reduced risk of major cardiovascular events in adults with type 2 diabetes and established cardiovascular disease
• Reduced risk of certain kidney outcomes in adults with type 2 diabetes and diabetic kidney disease with albuminuria
• Once-daily oral dosing

Some patients may experience modest weight loss and lower blood pressure as part of the SGLT2 class effect. Individual results vary.

Side Effects and Safety

• Increased urination, thirst, or dry mouth
• Genital yeast infections
• Urinary tract infections
• Nausea or constipation
• Dizziness or lightheadedness, especially on standing
• Fatigue

Serious risks are uncommon but important. These include diabetic ketoacidosis, severe urinary tract infections, kidney injury, severe genital infections (including rare cases of Fournier’s gangrene), volume depletion, bone fracture risk, and increased risk of lower-limb amputation seen in trials. Hypoglycemia can occur when Invokana is used with insulin or a sulfonylurea. Seek urgent medical care for symptoms suggesting ketoacidosis, severe infection, or an allergic reaction.

Drug Interactions and Cautions

Key considerations include:

• Diuretics may increase volume depletion and dizziness.
• Insulin and sulfonylureas raise hypoglycemia risk when combined.
• Enzyme inducers (for example, rifampin, phenytoin, phenobarbital, ritonavir) may reduce canagliflozin exposure.
• Digoxin levels may rise; monitoring is sometimes considered.
• Monitor kidney function and volume status, especially in older adults.

Invokana is often used with metformin for additive glucose control. Learn about this common baseline therapy at Metformin. Avoid very low-carbohydrate diets, heavy alcohol intake, or prolonged fasting without clinical guidance due to ketoacidosis risk with SGLT2 inhibitors.

What to Expect Over Time

Blood glucose often begins to improve within days. A1C reflects average glucose over about three months, so treatment impact is usually assessed over that time. Weight and blood pressure changes, when present, are generally gradual. Kidney and cardiovascular risk reduction benefits are evaluated over longer periods under clinician supervision.

Compare With Alternatives

Other SGLT2 inhibitors include Jardiance® (empagliflozin) and Farxiga® (dapagliflozin). For some patients, a fixed-dose combination such as Invokamet (canagliflozin with metformin) may be considered by a prescriber. Choice depends on medical history, kidney function, cardiovascular profile, and treatment goals.

Pricing and Access

Canadian pricing and US shipping help many patients compare Invokana price options. People often look up Invokana 100 mg price, Invokana 300 mg price, price of Invokana 100 mg, cost of Invokana 100 mg, and Invokana 300 mg tablets price when planning refills. Some also compare Canagliflozin price, Canagliflozin 100 mg price, and Canagliflozin 300 mg price to understand the market. If paying a cash price or estimating out-of-pocket cost, review the price on this page before checkout.

You can buy Invokana online through CanadianInsulin with secure checkout and prompt US delivery. For savings guidance, see Invokana Generic and current site offers on Promotions. To compare fill sizes, review the product options and select what matches your prescription.

Availability and Substitutions

Availability can vary by strength and quantity. When a specific option is not in stock, a prescriber may recommend a suitable alternative from the same class or a different class. Generic availability depends on market and regulatory status; consult the prescriber and pharmacy. Educational details on generics appear in the article linked above.

Patient Suitability and Cost Saving Tips

Good candidates often include adults with type 2 diabetes who need additional A1C lowering, or those with established cardiovascular disease, or diabetic kidney disease with albuminuria, when clinically appropriate. People with very low eGFR, severe dehydration, active foot ulcers, or a history of serious hypersensitivity may not be good candidates. Pregnancy and breastfeeding need individualized risk–benefit discussions with a clinician.

Cost-saving ideas include choosing a multi-month supply when appropriate, aligning refills with regular lab checks, and setting refill reminders. Compare quantities for the best unit pricing. You can schedule auto-reminders in your account and keep your prescription on file for faster reorders.

Questions to Ask Your Clinician

• Is Invokana appropriate for my type 2 diabetes goals and medical history?
• What starting dose fits my kidney function and current medications?
• How should I monitor for dehydration, genital infections, or ketoacidosis symptoms?
• Could Invokana be combined with metformin or other agents for better control?
• Do I need to pause this medicine before surgery or prolonged fasting?
• How often should I check labs to track kidney function and A1C?

Authoritative Sources

• Manufacturer Site
• FDA DailyMed
• Health Canada DPD

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