Please note: a valid prescription is required for all prescription medication.
Invokana (canagliflozin) tablets
Sitewide Super Sale - Get 15% off when you buy 3 or more of the same product using the code LESS15 at checkout.
Applies to all products originating from Canada. Maximum quantity limited to a 90-day supply per order.
Price range: $135.99 through $159.99
You save


Invokana (canagliflozin) is a prescription tablet in the SGLT2 inhibitor class for type 2 diabetes. This page summarizes dosing basics, safety, storage, and access factors that influence invokana price for cash-pay patients without insurance. Dispensing logistics may involve Ships from Canada to US, based on prescription requirements.
What Invokana Is and How It Works
Invokana contains canagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. This class lowers blood glucose by reducing glucose reabsorption in the kidneys, which increases glucose excretion in urine. Because the effect is tied to kidney filtration, kidney function is an important part of selection and follow-up. Some people also notice changes in urination and mild fluid loss, which can affect blood pressure.
Dispensing is handled by licensed Canadian pharmacies.
Beyond blood sugar control, the official indication set can include cardiovascular and kidney outcomes, depending on the approved labeling in a given country. For broader background on this medicine class, see SGLT2 Inhibitors and the overview article SGLT2 Inhibitor Drug Class. Care teams often review kidney labs before and during therapy. This is one reason the same prescription may not be appropriate for every person with diabetes.
Some orders may qualify for US delivery from Canada when documentation is complete and the product is eligible for cross-border referral fulfillment.
Who It’s For
Invokana is generally prescribed for adults with Type 2 Diabetes as part of an overall treatment plan that may include nutrition changes and other medicines. In U.S. labeling, it is indicated to improve glycemic control in adults with type 2 diabetes. The same labeling also includes risk-reduction indications for certain cardiovascular and kidney outcomes in specific patient groups. A prescriber determines whether those indications apply, based on history and lab results.
This medicine is not used for type 1 diabetes, and it is not a treatment for diabetic ketoacidosis (DKA). It may not be appropriate in people with severe kidney impairment, those on dialysis, or anyone with a serious hypersensitivity reaction to canagliflozin. People with frequent genital yeast infections, recurrent urinary infections, low blood pressure, or a history of foot ulcers may need additional screening and counseling before starting an SGLT2 inhibitor. Patient selection should follow the product monograph or prescribing information used by the dispensing pharmacy.
Why it matters: Kidney function affects both eligibility and how well SGLT2 inhibitors work.
Dosage and Usage
Invokana is taken by mouth once daily. In many product labels, dosing begins with 100 mg once daily, typically before the first meal of the day, and may be increased to 300 mg once daily in selected patients. Dose eligibility can depend on kidney function (for example, an estimated glomerular filtration rate, eGFR), as well as tolerability and concurrent therapies.
For anyone comparing access options, invokana price can vary by strength and the quantity supplied, so prescriptions should clearly state the intended dose and tablet strength. Patients using insulin or insulin secretagogues (such as sulfonylureas) may require closer monitoring for low blood sugar when an SGLT2 inhibitor is added. Clinicians may also give instructions for temporary interruption before surgery or during prolonged fasting to reduce DKA risk. These steps should be individualized and based on the official labeling.
- Administration timing: often before first meal
- Hydration: consider volume status
- Lab follow-up: kidney function checks
- Added therapies: monitor for hypoglycemia
Quick tip: Keep an updated medication list for travel or emergency visits.
Strengths and Forms
This medicine is supplied as an oral tablet. Common presentations include 100 mg and 300 mg strengths. In practice, prescribers select a strength based on treatment goals, kidney function, and the patient’s overall regimen. Availability can vary by pharmacy and by country-specific labeling, so the dispensed presentation should match the prescription exactly.
When comparing strengths, invokana price may differ between Invokana 100 mg tablets and invokana 300 mg tablets because the dose and package configurations can differ. The generic name is canagliflozin, which is useful when reviewing medication lists, lab orders, or interaction checks.
| Form | Strength | Route |
|---|---|---|
| Tablet | 100 mg | Oral |
| Tablet | 300 mg | Oral |
For additional non-insulin options often used alongside SGLT2 inhibitors, browsing the hub Non Insulin Medications can help frame what else may be in a regimen, without implying any switch or substitution.
Storage and Travel Basics
Store tablets at controlled room temperature, away from excess heat and moisture. Keep the bottle tightly closed and store it out of reach of children and pets. Do not transfer tablets into unmarked containers for long periods, since the original packaging helps preserve stability and reduces the risk of mix-ups.
For travel, keep tablets in carry-on luggage when flying, and bring a copy of the prescription or pharmacy label to support security checks and replacement needs. Avoid leaving medication in a parked car where temperatures can rise quickly. If a dose is missed, instructions in the patient information leaflet or product monograph should be followed; a clinician or pharmacist can clarify how to handle missed doses safely.
For education on diabetes management topics beyond a single product, the collection Type 2 Diabetes Articles can provide background on common therapy combinations and monitoring concepts.
Side Effects and Safety
Common side effects with SGLT2 inhibitors can include increased urination, thirst, genital yeast infections, and urinary tract infections. Some people may experience dizziness or lightheadedness, especially when starting therapy or when combined with diuretics. Because these effects relate to fluid and glucose in the urine, hydration status and personal infection history matter when evaluating tolerability.
Serious risks can include diabetic ketoacidosis (which can occur even if blood glucose is not extremely high), acute kidney injury, severe urinary infections, and rare but serious genital infections such as necrotizing fasciitis of the perineum (Fournier’s gangrene). Labeling for canagliflozin also includes cautions about lower-limb complications and fractures in some contexts. When reviewing benefit-risk tradeoffs, invokana price should never be the only consideration; the safety profile and monitoring plan matter.
When to seek urgent evaluation
Urgent evaluation is generally appropriate for symptoms that could signal DKA or severe infection. Concerning symptoms can include nausea, vomiting, abdominal pain, rapid breathing, confusion, unusual fatigue, fever, severe genital or perineal pain, or signs of dehydration such as fainting. Patients should follow their prescriber’s instructions for sick days, fasting, or surgery preparation. If severe symptoms occur, local emergency services or urgent care pathways should be used, rather than waiting for routine follow-up.
For a focused review of this class in cardiovascular settings, see Heart Failure Care Changes, which discusses class-wide considerations in plain language.
Drug Interactions and Cautions
Drug interactions with canagliflozin are often related to additive effects on blood sugar or fluid status. Combining an SGLT2 inhibitor with insulin or sulfonylureas can raise the risk of hypoglycemia, even though SGLT2 inhibitors alone have a lower hypoglycemia risk. Diuretics can increase the chance of low blood pressure and dehydration when used together with medicines that increase urination.
A valid prescription is required and may be verified.
Some medicines can change canagliflozin exposure through enzyme induction or inhibition, which may alter effectiveness or side effects. Digoxin levels may be affected in some cases, so monitoring may be considered. As a practical step, a complete medication list should include over-the-counter products and supplements. When people are comparing options, invokana price is only one variable; interaction risk and monitoring needs can change the overall suitability of therapy.
Kidney disease and heart failure histories may influence selection of an SGLT2 inhibitor versus another class. Background reading on kidney-related diabetes care is available in Chronic Kidney Disease and the article Dapagliflozin Kidney Health.
Compare With Alternatives
SGLT2 inhibitors are one of several non-insulin options used in type 2 diabetes. Within the same class, empagliflozin and dapagliflozin are common alternatives. Other classes used for glucose lowering include GLP-1 receptor agonists, DPP-4 inhibitors, metformin, and insulin, with selection based on comorbidities, kidney function, side-effect profiles, and patient-specific goals.
For class comparisons, the product pages for Jardiance Tablets and Farxiga Tablets provide basic presentation details, while comparative context is discussed in Invokana Vs Jardiance. Formulary status and dosing constraints can differ across products, which can affect day-to-day use. Even when two medicines are in the same class, monitoring plans and contraindications may not match.
When reviewing options with a clinician, a practical framework includes kidney function thresholds, history of recurrent infections, blood pressure status, and concurrent diuretic therapy. These factors often matter as much as invokana price when deciding which therapy is most appropriate for a given patient.
For a dosing-focused discussion of dapagliflozin as an alternative, see Farxiga Dosing Guide.
Pricing and Access: invokana price considerations
Costs for prescription diabetes medicines can vary widely based on strength, days’ supply, and whether the prescription is filled through an insurance benefit or a cash-pay pathway. Some patients compare the retail pharmacy amount with other fulfillment options, including referral-based cross-border access models, when permitted by documentation and dispensing rules. Coverage rules can also differ for Medicare Part D, commercial insurance, and employer plans, so the same medication may have different out-of-pocket amounts across patients.
Cash-pay access is available when insurance is not used.
Practical steps that may help reduce confusion when comparing costs include confirming the prescribed strength (100 mg vs 300 mg), ensuring the quantity matches the intended days’ supply, and checking whether prior authorization is required by an insurer. Site-wide updates may be listed on the Available Promotions page, where applicable. Browsing Diabetes Medications can also help patients understand what categories exist, without implying that alternatives are interchangeable.
Authoritative Sources
U.S. indications and safety details are summarized in the FDA application overview.
Patient-focused medication guidance is available from MedlinePlus canagliflozin.
To proceed with dispensing and delivery options, select prompt, express, cold-chain shipping during checkout if offered for the shipment type.
This content is for informational purposes only and is not a substitute for professional medical advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What is Invokana used for?
It is an SGLT2 inhibitor for adults with type 2 diabetes to improve glycemic control. It also has labeled benefits in certain cardiovascular and kidney outcomes for appropriate patients.
How do I take Invokana?
Take once daily before the first meal. The usual starting dose is 100 mg, with some patients increased to 300 mg based on kidney function and tolerability per the label.
Who should not take Invokana?
Avoid if you have type 1 diabetes, active ketoacidosis, are on dialysis, or had a serious hypersensitivity to canagliflozin. Discuss severe renal impairment or frequent genital infections with your clinician.
What are common side effects?
Genital yeast infections, urinary tract infections, increased urination, thirst, nausea, constipation, and dizziness. Serious risks include ketoacidosis, dehydration, severe urinary infections, and rare perineal infections.
Can Invokana cause hypoglycemia?
On its own, the risk is low. The risk increases when used with insulin or sulfonylureas, so clinicians may monitor and adjust therapy as needed.
How should I store Invokana tablets?
Store at room temperature in a dry place, in the original container, and keep away from children and pets. Do not use expired or damaged tablets.
Are there interactions with other medicines?
Diuretics, antihypertensives, insulin, and sulfonylureas may require caution. Rifampin can reduce exposure, and canagliflozin may increase digoxin levels. Review all medicines with your provider.
What is Invokana used for?
Invokana (canagliflozin) is an oral prescription medicine in the SGLT2 inhibitor class. In U.S. labeling, it is indicated to improve blood glucose control in adults with type 2 diabetes, alongside diet and exercise. The prescribing information also includes certain cardiovascular and kidney risk-reduction indications for specific patient groups. Whether those additional indications apply depends on an individual’s medical history and lab results. A prescriber can confirm which labeled uses match a given patient’s situation.
How does canagliflozin lower blood sugar?
Canagliflozin works in the kidneys by inhibiting a transporter called SGLT2 (sodium-glucose cotransporter 2). This reduces glucose reabsorption back into the bloodstream and increases glucose excretion in the urine. Because the mechanism depends on kidney filtration, kidney function can affect both how well the medicine works and whether it is appropriate. The same process can lead to increased urination and mild fluid loss in some people, which is why hydration status and blood pressure are often reviewed during follow-up.
What should be monitored while taking Invokana?
Monitoring commonly includes kidney function tests (such as serum creatinine and eGFR) before starting and periodically after. Clinicians may also review blood pressure, volume status (dehydration risk), and blood glucose or A1C to assess response. People using insulin or sulfonylureas may need closer monitoring for hypoglycemia when canagliflozin is added. Because genital and urinary infections can occur, symptoms such as burning with urination, fever, or unusual genital irritation should be discussed promptly with a clinician.
Can Invokana be used with insulin or metformin?
Invokana may be prescribed alongside other diabetes medicines, including metformin and insulin, depending on a patient’s regimen and goals. When combined with insulin or sulfonylureas, the overall treatment can increase the risk of low blood sugar, even though SGLT2 inhibitors alone have a lower hypoglycemia risk. Clinicians often consider kidney function, blood pressure, infection history, and concurrent diuretic use when adding canagliflozin. Medication combinations should follow the prescribing information and individualized medical guidance.
What are warning signs of diabetic ketoacidosis with SGLT2 inhibitors?
Diabetic ketoacidosis (DKA) is a serious condition that can occur with SGLT2 inhibitors, sometimes with less markedly elevated blood glucose than expected. Symptoms can include nausea, vomiting, abdominal pain, rapid or deep breathing, confusion, unusual fatigue, or a fruity odor on the breath. Risk can rise during prolonged fasting, acute illness, heavy alcohol intake, or around surgery. Patients should follow prescriber instructions for sick days and pre-procedure medication holds, and seek urgent care for severe symptoms.
What questions should I ask my clinician before starting Invokana?
Useful questions include: whether kidney function is adequate for canagliflozin, how often labs should be checked, and what symptoms should trigger urgent evaluation. It also helps to ask about dehydration risk if taking diuretics, and how to manage the medicine around surgery, fasting, or acute illness. Patients may want to discuss prior urinary or genital infections, foot problems, fracture risk, and other medicines that might interact. Bringing an up-to-date medication list, including supplements, can make the review more complete.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
You Might Also Like
Related Articles
Awiqli Once-Weekly Insulin Icodec Use: Practical Basics
Key TakeawaysOnce-weekly basal insulin can simplify routines, but it also changes how you plan. This article explains awiqli in plain language, with clinical context. You will learn what “insulin icodec”…
Sibutramine FDA Ban Explained: Risks, Timeline, Context
Key Takeaways Withdrawal was risk-driven based on higher rates of serious events. Heart and stroke concerns shaped the final regulatory decisions. Not a simple “diet pill” story; outcomes data changed…
Ozempic Eating Disorder Risks and Screening for Safer Care
Key TakeawaysDiscuss ozempic eating disorder concerns before starting appetite-altering medicines.Appetite suppression can help some people, but also trigger restriction.Screening should cover bingeing, purging, laxative misuse, and body image distress.Monitoring matters…
Low Income Medication Help: Steps To Reduce Prescription Costs
Key TakeawaysIf low income medication costs are forcing tough choices, focus on the “next refill” problem first.Start with your exact drug name and strengthCompare cash, insurance, and assistance pathwaysAsk about…


