Clopidogrel

Uses of Clopidogrel

Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease).

It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent).

Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.

Precautions and Warnings

Before taking clopidogrel, tell your doctor or pharmacist if you are allergic to it; or to similar antiplatelet drugs (thienopyridines such as prasugrel); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• bleeding conditions (such as stomach ulcers, bleeding in the brain/eye)
• recent surgery
• serious injury/trauma
• liver disease
• bleeding disease (such as hemophilia)

To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may instruct you to stop clopidogrel for at least 5 days before surgery. Do not stop taking clopidogrel without talking with your heart doctor (cardiologist) first.

This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Dosage

The dosage of Clopidogrel depends on the condition being treated and individual patient factors, such as age, weight, and medical history.

Side Effects

Common Side Effects:

• Easy bleeding/bruising,
• Stomach upset/pain,
• Diarrhea,
• Constipation

Serious Side Effects:

• Severe Bleeding;
• Allergic Reactions;
• Thrombocytopenic Purpura (TTP);
• Liver Problems -Yellowing of the skin or eyes (jaundice), dark urine, or severe fatigue may indicate liver damage;
• Severe Skin Reactions