Humira® Prefilled Pen for Autoimmune Conditions

Humira® is a prescription biologic that targets tumor necrosis factor to help control inflammation in several immune-mediated diseases. This page explains approved uses, safety essentials, and ordering details with US shipping from Canada so you can plan treatment and costs without insurance. Use it to review key points and prepare questions for your prescriber.

What Humira Is and How It Works

Humira® contains adalimumab, a monoclonal antibody that binds tumor necrosis factor (TNF). By neutralizing TNF, it can reduce inflammatory signaling implicated in conditions such as arthritis, psoriatic disease, and inflammatory bowel disease. The humira medication is supplied for subcutaneous use and is intended for ongoing, long-term management when prescribed.

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This medicine is typically used under the supervision of a clinician. Baseline screening for tuberculosis and hepatitis B is commonly recommended before starting therapy. Your provider may also check blood counts and consider vaccination status, avoiding live vaccines during treatment.

Who It’s For

This treatment is indicated for adults with moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. It is also indicated for moderate to severe Crohns disease and ulcerative colitis. Additional uses include hidradenitis suppurativa, certain types of uveitis, and juvenile idiopathic arthritis in appropriate pediatric patients.

People with active, serious infections should not start this therapy. Those with recurrent infections, chronic or localized infections, demyelinating disease, moderate to severe heart failure, or a history of certain cancers should discuss risks in detail. The humira prefilled pen supports at-home administration across these approved conditions when your prescriber confirms suitability. For specific condition pages, see Rheumatoid Arthritis, Crohns Disease, Plaque Psoriasis, and Ankylosing Spondylitis.

Dosage and Usage

Use this medicine exactly as prescribed. Many adults inject every other week; some conditions or patient factors may lead a clinician to adjust the schedule. Your prescriber will advise on any loading doses, timing changes, or temporary holds around infections or procedures.

Use the humira auto injector or prefilled syringe on clean, intact skin of the abdomen or thigh. Rotate sites, and avoid areas that are red, bruised, or scarred. Let the pen come to room temperature out of the carton before use, but do not heat it. Follow the Instructions for Use that come with your device, and contact your clinician if you have injection questions.

Strengths and Forms

Common presentations include single-use prefilled pens and prefilled syringes for subcutaneous use. Typical adult maintenance options include 40 mg and a higher 80 mg presentation. Availability may vary by pharmacy and pack size. Your prescription will specify the device and quantity.

Missed Dose and Timing

If you miss a dose, inject as soon as you remember unless it is close to the next scheduled dose. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double doses. If you are unsure what to do, contact your prescriber or pharmacist.

Storage and Travel Basics

Store unopened pens and syringes in the refrigerator in the original carton to protect from light. Do not freeze. If a pen has been frozen, do not use it. For short trips, keep products in an insulated bag with cool packs, avoiding direct contact with ice. Many patients travel with a copy of their prescription and the product carton.

When traveling, keep the humira pen injector in carry-on luggage. Follow the label for any room-temperature allowances and time limits; once a product has been kept at room temperature, do not refrigerate it again. Keep out of reach of children. Dispose of used devices in a puncture-resistant sharps container.

Pen Handling and Sharps Disposal

Read the device Instructions for Use before the first injection. Wash hands, prepare the site, and do not remove the cap until you are ready to inject. Place the pen at a 90-degree angle and activate as directed. Hold it in place for the full hold time so the dose can finish. You may hear a click or see a window indicator change during the injection.

After use, place the pen or syringe into an FDA-cleared sharps disposal container. When it is nearly full, follow local rules for disposal. Never throw used sharps directly into household trash or recycling.

Benefits

TNF inhibition can reduce signs and symptoms of inflammatory disease and may improve physical function. Many patients appreciate less frequent dosing compared with some therapies. The device is designed for self-injection at home, reducing clinic visits for administration. Your experience can vary by condition, prior therapies, and coexisting health factors.

Side Effects and Safety

• Injection site reactions: redness, swelling, itching, pain
• Upper respiratory symptoms: stuffy nose, sore throat
• Headache or nausea
• Rash
• Back or joint pain

Serious risks can include severe infections such as tuberculosis, invasive fungal disease, or opportunistic infections. There is a risk of hepatitis B reactivation, certain malignancies including lymphoma and skin cancers, new or worsening demyelinating disease, heart failure, cytopenias, and lupus-like reactions. Seek urgent care if you develop fever, persistent cough, shortness of breath, night sweats, unexplained weight loss, or unusual bruising or bleeding.

Live vaccines should generally be avoided during therapy. Tell your clinician about all medicines, including other biologics, corticosteroids, methotrexate, and immunosuppressants. Review the full Prescribing Information for complete safety details.

Drug Interactions and Cautions

Combining this treatment with other biologic immunomodulators (for example, anakinra or abatacept) may increase infection risk. Discuss all prescription and over-the-counter medicines, vitamins, and herbal supplements with your healthcare provider. Notify your care team if you have diabetes, chronic lung disease, neurologic symptoms, or heart failure. Report any signs of infection before each dose.

What to Expect Over Time

Responses can vary. Some people notice gradual changes over several dosing intervals, while others take longer. Your clinician may track symptoms, flares, and lab markers to assess response. Consistent dosing and proper injection technique can help maintain steady disease control. If you miss several doses, your prescriber will advise how to restart.

Compare With Alternatives

Other biologic options may be appropriate if you cannot continue or do not respond. A TNF inhibitor such as Enbrel SureClick may be considered for some arthritis indications. For certain psoriatic or gastrointestinal indications, an interleukin inhibitor such as Stelara Syringe may be discussed with your prescriber. Choice depends on diagnosis, prior therapies, comorbidities, and safety factors.

Pricing and Access

We offer Canadian pricing with transparent checkout and US fulfillment. Actual humira cost varies by device, quantity, and your prescription. If you use cash pay, you can compare options by pack size. Those seeking assistance can review programs and eligibility on our site; see current offers on Promotions. For patients comparing cross-border options, this item Ships from Canada to US with prescription validation. We use encrypted checkout to protect your information.

Availability and Substitutions

Supply can change by device and pack size. If the item is temporarily unavailable, your prescriber may recommend a suitable alternative or a clinically appropriate biosimilar. For context on interchangeability, see our overview on Biosimilar Drugs. We cannot guarantee restock timing; your care team can advise on medically appropriate substitutions.

Patient Suitability and Cost-Saving Tips

This therapy may suit patients with moderate to severe inflammatory disease who have had inadequate response or intolerance to conventional agents. It may not suit those with active serious infection, uncontrolled chronic infections, or certain neurologic or cardiac conditions. Discuss pregnancy, breastfeeding, and vaccination plans with your clinician.

To reduce visits, ask about multi-month supplies when clinically appropriate, and consider aligning refills to limit separate shipments. Set reminders for dosing and renewals. If you are comparing humira pen price across sources, review device type and quantity to keep comparisons consistent. Your prescriber and pharmacist can help you match the prescribed device to the most economical pack for your regimen.

Questions to Ask Your Clinician

• Screening needed: TB, hepatitis B, or other labs
• Dosing schedule: standard interval versus adjusted timing
• Device choice: pen versus syringe for ease of use
• Vaccinations: which ones to receive before starting
• Infection plan: what to do if you develop symptoms
• Monitoring: labs or visits recommended over time
• Travel: how to store and carry this medicine

Authoritative Sources

For complete label information and device details, review the manufacturer’s resources and official regulators: see the manufacturer’s US Prescribing Information on the AbbVie site, the DailyMed listing, and Health Canada’s Drug Product Database.

• US Prescribing Information
• DailyMed Label
• Health Canada DPD

Ready to proceed? You can place your order with prompt, express, cold-chain shipping after your prescription is verified.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.