Invokana

Invokana (canagliflozin) is an oral medication used to improve blood sugar control in adults with type 2 diabetes. It works by helping the kidneys remove excess glucose through urine and offers additional benefits for heart and kidney health. Invokana is often prescribed alongside diet and exercise and can help reduce the risk of cardiovascular events and slow the progression of kidney disease.

Benefits:

• Lowers blood sugar levels in adults with type 2 diabetes.
• Reduces the risk of major cardiovascular events, such as heart attack and stroke.
• Slows the progression of chronic kidney disease and reduces the risk of kidney failure.
• Promotes modest weight loss by removing excess glucose and calories through urine.
• Helps reduce blood pressure in some individuals.

Dosage:

• The starting dose is typically 100 mg once daily, taken before the first meal of the day.
• Based on your response and healthcare provider’s recommendation, the dose may be increased to 300 mg daily.
• Always follow your healthcare provider’s dosing instructions.

Warnings and Precautions:

• Invokana may increase the risk of lower-limb amputation, particularly in individuals with a history of foot ulcers or poor circulation. Monitor for signs of foot issues and maintain good foot care.
• Use with caution if you have kidney problems; regular monitoring of kidney function is recommended.
• May cause or worsen dehydration, leading to symptoms such as dizziness or fainting. Stay well-hydrated.
• Invokana can increase the risk of urinary tract infections and genital yeast infections. Seek medical attention if symptoms occur.
• In rare cases, it may cause Fournier’s gangrene (a serious infection of the genital area). Watch for pain, redness, or swelling.
• May lead to ketoacidosis, even with normal blood sugar levels. Seek immediate care if you experience nausea, vomiting, abdominal pain, or difficulty breathing.
• Not recommended for individuals with type 1 diabetes or diabetic ketoacidosis.
• Avoid use during pregnancy or breastfeeding unless directed by your healthcare provider.

Usage Instructions:

• Take Invokana once daily, preferably before the first meal.
• Swallow the tablet whole with water.
• Follow your healthcare provider’s advice on diet, exercise, and any other medications for optimal results.

Storage Information:

• Store Invokana at room temperature, between 68°F to 77°F (20°C to 25°C).
• Keep in its original container, tightly closed, and away from moisture or excessive heat.
• Keep out of reach of children.

Common Side Effects:

• Increased urination due to the glucose removal process.
• Genital yeast infections, particularly in women.
• Mild dehydration, causing thirst or dry mouth.
• Low blood sugar (hypoglycemia) when used with other diabetes medications.
• Urinary tract infections, with symptoms like burning during urination or frequent urges to urinate. 

More information about Invokana:

• Product Monograph – Health Canada
• U.S. Food and Drug Administration Medication Guide