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Ketoderm® Cream for Fungal Skin Infections
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This antifungal cream contains ketoconazole and treats athlete’s foot, jock itch, ringworm, and tinea versicolor. This page summarizes approved uses, safe application, and how to compare options, with US delivery from Canada. You can also review pricing and ways to save without insurance.
What Ketoderm Is and How It Works
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The active ingredient, ketoconazole, is an imidazole antifungal that inhibits fungal 14α-demethylase. Blocking ergosterol synthesis weakens the fungal cell membrane, which can limit growth and help clear superficial infections. Systemic exposure is minimal when used on intact skin as directed.
Topical ketoconazole is used for dermatophyte and yeast infections of the skin, including tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea corporis (ringworm), and pityriasis versicolor. It is not designed for nails, scalp, or deep infections. Avoid ocular, oral, or intravaginal use.
Who It’s For
This treatment is for adults and adolescents with clinician-diagnosed superficial fungal skin infections susceptible to ketoconazole. It may be considered when over-the-counter antifungals are inadequate or when a prescriber prefers an imidazole agent. People with known hypersensitivity to ketoconazole or any cream component should not use it. Tell a clinician about pregnancy, breastfeeding, or extensive broken skin before starting.
If diabetes or impaired immunity increases your risk of recurrent rashes, you may benefit from preventive skin care guidance. For background on how high glucose relates to rashes, see Fungal Skin Issues. For out-of-pocket planning, see Ketoderm® cream price without insurance in Pricing and Access.
Dosage and Usage
Follow the approved label and your prescriber’s instructions. Clean and dry the affected area before each application. Apply a thin film to the involved skin and about 1 inch beyond the visible margin. Use gentle, even strokes to cover the area without heavy rubbing. Wash hands after use unless hands are the treated site. Do not use dressings that trap heat or moisture unless instructed by a clinician.
Typical regimens involve once-daily application for a set period determined by infection type and site. Continue for the full prescribed duration, even if symptoms improve earlier. Avoid contact with eyes, inside the nose, mouth, or genital mucosa. Do not use on open wounds. Stop use and seek medical advice if severe irritation or an allergic reaction occurs.
Strengths and Forms
This product is commonly supplied as ketoconazole 2% cream in tubes. Pack sizes vary by pharmacy; 15 g and 30 g presentations are frequently available. Availability can differ by location and stock.
Missed Dose and Timing
If a scheduled application is missed, apply when remembered the same day. If it is close to the next scheduled time, skip the missed dose and resume the usual schedule. Do not double-apply to “catch up.” Maintain consistent daily use to support effectiveness.
Storage and Travel Basics
Store the cream at typical room temperature per the label. Keep the cap tightly closed when not in use. Protect from excessive heat and direct light. Do not freeze. Keep out of reach of children and pets. When traveling, carry the tube in its original carton within hand luggage. Pack a copy of the prescription if available, and allow time for security screening. For long trips, bring enough supply plus a buffer, and keep the label intact so agents can verify contents.
Benefits
This medicine targets common dermatophytes and select yeasts on the skin. Localized use limits systemic exposure. Once-daily schedules are common, which can simplify routines. The treatment can be used on many body sites where superficial infections occur, as long as skin is intact and directions are followed. Consistent, thin applications may help minimize irritation.
Side Effects and Safety
- Mild burning or stinging at the application site
- Itching or redness where applied
- Dryness or peeling with continued use
- Rare contact dermatitis or rash
Serious reactions are uncommon. Stop use and get medical help if swelling, blistering, hives, or signs of severe allergy develop. Because absorption through intact skin is low, systemic effects are unlikely. Do not use near the eyes or on mucous membranes. Infections that worsen or spread require clinical review to confirm diagnosis and rule out non-fungal causes.
Drug Interactions and Cautions
Topical ketoconazole has limited interaction potential compared with oral azoles. Still, avoid layering multiple strong topicals on the same area without guidance, including keratolytics, retinoids, or potent corticosteroids, which may increase irritation. Do not occlude unless directed. If lesions are actually viral or eczematous, a different class may be indicated, such as Zovirax Oint 5 for herpes lesions or Tacrolimus Hgc for certain eczematous flares, as clinically appropriate. Always confirm diagnosis with a clinician.
What to Expect Over Time
Irritation may lessen as the skin recovers, but mild dryness can occur as scaling resolves. Some discoloration from tinea versicolor may persist after the fungus is cleared and fades gradually with normal skin turnover. Adherence to the full course is important. For transparency during checkout, the Ketoderm cash price displays before payment. If symptoms do not improve or new symptoms appear, consult a healthcare professional for reassessment.
Compare With Alternatives
Other topical antifungals can be appropriate based on organism, site, and tolerance. Azole-class generics such as Ketoconazole may offer a similar mechanism. Allylamines like Terbinafine are often selected for dermatophyte infections. The best option depends on infection type, location, and prior response. Your prescriber will choose a regimen aligned with the diagnosis and medical history.
Pricing and Access
Pricing reflects Canadian supply. Many customers check available promotions before placing a request. If seeking deals, look for a Ketoderm cream coupon on our site or visit Promotions. We list Ketoconazole 2% cream price transparently, with US delivery from Canada for eligible orders. Checkout uses encrypted processes to help protect your information.
Availability and Substitutions
Stock can vary by pharmacy and region. If a selected size is unavailable, a prescriber may recommend a comparable alternative or a different pack size. You can Order Ketoderm® cream online once the prescription is reviewed, or proceed with a suitable substitute if advised.
Patient Suitability and Cost-Saving Tips
Good candidates typically have a confirmed superficial fungal rash on intact skin. Those with severe inflammation, extensive involvement, or unclear diagnosis should be evaluated before starting. People with chronic conditions that impair healing may need closer follow-up.
- Multi-tube planning: Consider a 30 g tube if larger areas are treated.
- Refill timing: Set reminders so treatment is not interrupted mid-course.
- Compare options: Use our tools for Ketoderm cream cost comparison against similar antifungals.
- Self-pay strategies: Review Canadian pricing, then choose the pack size that fits your course length.
- Separate needs: For animal therapies, see Pet Medications.
Questions to Ask Your Clinician
- Which skin infection is suspected, and how was it diagnosed?
- Is this antifungal the right class for the organism and site?
- How long should the application continue after visible clearing?
- What signs of irritation or allergy should prompt a recheck?
- Can I use a mild moisturizer between doses to reduce dryness?
- Are there activities or products that could delay recovery?
- What alternative antifungals are appropriate if this is not tolerated?
Authoritative Sources
For full prescribing information and official references, see:
Ready to proceed? Submit your request for express US delivery from Canada. Temperature-controlled handling when required. This page is informational and not a substitute for medical advice; always follow the approved label and your clinician’s directions.
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Can this cream be used for seborrheic dermatitis?
Ketoconazole is used for several fungal skin infections. For seborrheic dermatitis, many clinicians prefer ketoconazole shampoo on the scalp and sometimes short courses of topical agents for affected facial or chest areas when appropriate. The cream may be prescribed for specific sites, but it is not intended for use in the eyes or on mucous membranes. Follow your clinician’s instructions and the approved label for the targeted condition and location.
Is it safe to apply on the face?
Facial use can be appropriate for certain diagnosed fungal rashes, but the cream should not contact the eyes, inside the nose, or lips. Apply a thin layer on intact skin only, avoiding areas with open wounds. If stinging, redness, or swelling worsens after several applications, stop and contact a healthcare professional. Sun sensitivity is not typical, but gentle skin care and avoiding harsh cleansers around the treated area can help limit irritation.
How long should treatment continue?
Duration depends on infection type, location, and clinical response. Many skin infections require consistent daily application for a defined course, and some need a brief period of continued use after symptoms improve. Because regimens vary, rely on the official label and your prescriber’s plan. If there is no improvement or if the rash spreads, request a re-evaluation to confirm the diagnosis and rule out non-fungal causes such as eczema or bacterial infection.
Can I use it with a topical steroid?
Combining products can increase irritation. Mild corticosteroids are sometimes used for short periods when inflammation is prominent, but only under medical guidance. Strong steroids, keratolytics, or retinoids layered on the same site may worsen stinging or dryness. If a steroid is required for eczema-like flares, your clinician may consider alternatives such as tacrolimus ointment. Keep applications thin, avoid occlusion unless directed, and report persistent irritation.
What should I do if irritation occurs?
Mild burning or itching often improves as the skin recovers. If intense redness, swelling, blistering, or hives appear, stop use and seek medical advice promptly. Recheck the diagnosis if symptoms persist, as non-fungal conditions can mimic these rashes. Using a gentle, non-comedogenic moisturizer between doses can help dryness on intact skin. Avoid fragrance-heavy soaps and hot water on the affected area while the skin barrier heals.
Does this treat nail fungus (onychomycosis)?
Topical ketoconazole cream is not indicated for nail infections. Nails are difficult for creams to penetrate, and alternative therapies are usually needed for onychomycosis. If nail involvement is suspected, ask a clinician about confirmation testing and appropriate treatments. Keeping feet dry, trimming nails straight across, and disinfecting nail tools can support overall care while a suitable antifungal regimen is determined.
Is it suitable during pregnancy or breastfeeding?
Data for topical ketoconazole in pregnancy and breastfeeding are limited. Systemic absorption is low when used on intact skin, but risks and benefits should be considered on a case-by-case basis. Avoid applying on the breast if nursing to prevent infant contact. Discuss current status, application sites, and alternative options with your prescriber to determine whether this therapy is appropriate for you.
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