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Nucynta ER 

Please note: a valid prescription is required for all prescription medication.

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Nucynta ER (extended-release tapentadol) is a prescription medication used to manage severe, chronic pain requiring around-the-clock treatment when other pain relief options are inadequate. It is classified as an opioid analgesic, combining pain relief effects with norepinephrine reuptake inhibition, making it effective for managing specific types of pain, including neuropathic pain related to diabetic peripheral neuropathy (DPN).

Benefits:

  • Provides extended pain relief for chronic, severe pain conditions
  • Effective in managing pain associated with diabetic peripheral neuropathy
  • Offers dual-action pain control as an opioid receptor agonist and norepinephrine reuptake inhibitor
  • Allows for less frequent dosing compared to immediate-release options
  • Designed for consistent, long-term pain management

Dosage:

  • The starting dose is typically 50 mg every 12 hours, depending on pain severity and prior opioid use
  • Dosage adjustments are made gradually, based on individual tolerance and pain control needs
  • The maximum recommended dose is 500 mg per day, split into two doses
  • Swallow tablets whole with water. Do not chew, crush, or split the tablet to avoid a rapid release of the medication

Usage Instructions:

  • Take Nucynta ER exactly as prescribed by your healthcare provider
  • Use the medication at the same times each day for consistent pain relief
  • Avoid alcohol and sedatives while on this medication, as they can increase the risk of side effects
  • Do not stop using Nucynta ER suddenly to prevent withdrawal symptoms; tapering off is advised under medical supervision
  • Consult your doctor if your pain is not adequately controlled or if you experience severe side effects

Storage Information:

  • Store Nucynta ER at room temperature, between 68°F and 77°F (20°C to 25°C)
  • Keep in its original container, away from moisture, heat, and light
  • Ensure the medication is stored securely and out of reach of children and others to prevent misuse

Warnings and Precautions:

  • This medication has a high risk of addiction, abuse, and misuse, even at prescribed doses
  • Not suitable for short-term pain relief or mild pain conditions
  • May cause respiratory depression, especially at higher doses or when combined with sedatives
  • Avoid driving or operating heavy machinery while using this medication, as it may cause drowsiness or dizziness
  • Inform your healthcare provider of any liver, kidney, or respiratory issues before starting Nucynta ER
  • Not recommended during pregnancy or breastfeeding unless deemed necessary by a doctor

Common Side Effects:

  • Nausea, vomiting, or constipation
  • Dizziness or drowsiness
  • Headache or fatigue
  • Dry mouth
  • Sweating

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